Search Results - "McCloskey, Daniel P"

Morphometry of hilar ectopic granule cells in the rat by Pierce, Joseph P., McCloskey, Daniel P., Scharfman, Helen E.

“…Granule cell (GC) neurogenesis in the dentate gyrus (DG) does not always proceed normally. After severe seizures (e.g., status epilepticus [SE]) and some other…”
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Depression of Synaptic Transmission by Vascular Endothelial Growth Factor in Adult Rat Hippocampus and Evidence for Increased Efficacy after Chronic Seizures by McCloskey, Daniel P, Croll, Susan D, Scharfman, Helen E

“…In addition to its potent effects on vasculature, it has become clear that vascular endothelial growth factor (VEGF) has effects on both neurons and glia, and…”
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Stereological methods reveal the robust size and stability of ectopic hilar granule cells after pilocarpine-induced status epilepticus in the adult rat by McCloskey, Daniel P., Hintz, Tana M., Pierce, Joseph P., Scharfman, Helen E.

“…Following status epilepticus in the rat, dentate granule cell neurogenesis increases greatly, and many of the new neurons appear to develop ectopically, in the…”
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Changes in hippocampal function of ovariectomized rats after sequential low doses of estradiol to simulate the preovulatory estrogen surge by Scharfman, Helen E., Hintz, Tana M., Gomez, Juan, Stormes, Kerry A., Barouk, Sharon, Malthankar-Phatak, Gauri H., McCloskey, Daniel P., Luine, Victoria N., MacLusky, Neil J.

“…In adult female rats, robust hippocampal changes occur when estradiol rises on the morning of proestrus. Whether estradiol mediates these changes, however,…”
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Brain IL-6 elevation causes neuronal circuitry imbalances and mediates autism-like behaviors by Wei, Hongen, Chadman, Kathryn K., McCloskey, Daniel P., Sheikh, Ashfaq M., Malik, Mazhar, Brown, W. Ted, Li, Xiaohong

“…Abnormal immune responses have been reported to be associated with autism. A number of studies showed that cytokines were increased in the blood, brain, and…”
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Postnatal neurogenesis as a therapeutic target in temporal lobe epilepsy by Scharfman, Helen E, McCloskey, Daniel P

“…Summary After it was first identified that seizures increase neurogenesis in the adult brain of laboratory animals, the idea that postnatal neurogenesis may be…”
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C-Fos activation in the periaqueductal gray following acute morphine-3β- d -glucuronide or morphine administration by Arout, Caroline A, Caldwell, Megan, McCloskey, Daniel P, Kest, Benjamin

“…Abstract Morphine-3β- d -glucuronide (M3G), a primary morphine metabolite, evokes hyperalgesia in mice and rats and putatively mediates hyperalgesia associated…”
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Aberrant hippocampal Atp8a1 levels are associated with altered synaptic strength, electrical activity, and autistic-like behavior by Kerr, Daniel J., Marsillo, Alexandra, Guariglia, Sara R., Budylin, Tatyana, Sadek, Rodina, Menkes, Silvia, Chauhan, Abha, Wen, Guang Y., McCloskey, Daniel P., Wieraszko, Andrzej, Banerjee, Probal

“…Type IV ATPases are putative aminophospholipid translocases (APLTs), more commonly known as flippases. A pronounced induction of the flippase Atp8a1 was…”
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Progressive, potassium-sensitive epileptiform activity in hippocampal area CA3 of pilocarpine-treated rats with recurrent seizures by McCloskey, Daniel P, Scharfman, Helen E

“…Summary Rat hippocampal area CA3 pyramidal cells synchronously discharge in rhythmic bursts of action potentials after acute disinhibition or convulsant…”
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Mossy fibers are the primary source of afferent input to ectopic granule cells that are born after pilocarpine-induced seizures by Pierce, Joseph P., Melton, Jay, Punsoni, Michael, McCloskey, Daniel P., Scharfman, Helen E.

“…Granule cell (GC) neurogenesis increases following seizures, and some newborn GCs develop in abnormal locations within the hilus. These ectopic GCs (EGCs)…”
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A Rat Model of Epilepsy in Women: A Tool to Study Physiological Interactions between Endocrine Systems and Seizures by Scharfman, Helen E, Malthankar-Phatak, Gauri H, Friedman, Daniel, Pearce, Patrice, McCloskey, Daniel P, Harden, Cynthia L, MacLusky, Neil J

“…Epilepsy in women is influenced by endocrine status and antiepileptic drugs, but without an animal model, the effects of endocrine variables and antiepileptic…”
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Modulation of vascular endothelial growth factor (VEGF) expression in motor neurons and its electrophysiological effects by McCloskey, Daniel P, Hintz, Tana M, Scharfman, Helen E

“…Abstract Previous studies have shown that VEGF expression in forebrain increases after experimental manipulations that increase neuronal activity. One question…”
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Mossy cell axon synaptic contacts on ectopic granule cells that are born following pilocarpine-induced seizures by Pierce, Joseph P., Punsoni, Michael, McCloskey, Daniel P., Scharfman, Helen E.

“…Granule cell neurogenesis increases following seizures, and some newly born granule cells develop at abnormal locations within the hilus. These ectopic granule…”
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Exercise influences spatial learning in the radial arm maze by Anderson, Brenda J, Rapp, David N, Baek, David H, McCloskey, Daniel P, Coburn-Litvak, Pamela S, Robinson, John K

“…Previous studies indicate that the hippocampus is active during exercise, and that neurotrophin expression, receptor density, and survival of dentate gyrus…”
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Aging-induced Seizure-related Changes to the Hippocampal Mossy Fiber Pathway in Forebrain Specific BDNF Overexpressing Mice by Weidner, Kate L, Goodman, Jeffrey H, Chadman, Kathryn K, McCloskey, Daniel P

“…Aging confers an increased risk for developing seizure activity, especially within brain regions that mediate learning and synaptic plasticity. Brain derived…”
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Exercise increases metabolic capacity in the motor cortex and striatum, but not in the hippocampus by McCloskey, Daniel P., Adamo, David S., Anderson, Brenda J.

“…Acute bouts of exercise have been shown to produce transient increases in regional cerebral glucose utilization, oxygen uptake, and cerebral blood flow in…”
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Exercise as an intervention for the age-related decline in neural metabolic support by Anderson, Brenda J, Greenwood, Shayri J, McCloskey, Daniel

“…To identify interventions for brain aging, we must first identify the processes in which we hope to intervene. Brain aging is a period of decreasing functional…”
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A Rat Model of Epilepsy in Women: A Tool to Study Physiological Interactions Between Endocrine Systems and Seizures by Scharfman, Helen E., Malthankar-Phatak, Gauri H., Friedman, Daniel, Pearce, Patrice, McCloskey, Daniel P., Harden, Cynthia L., MacLusky, Neil J.

“…Epilepsy in women is influenced by endocrine status and antiepileptic drugs (AEDs), but without an animal model, the effects of endocrine variables and AEDs…”
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Exercise as an intervention for the age-related decline in brain metabolic support by Brenda J Anderson, Shayri J Greenwood, Daniel P McCloskey

“…To identify interventions for brain aging, we must first identify the processes in which we hope to intervene. Brain aging is a period of decreasing functional…”
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