Search Results - "McCleish, Amanda T."

Evidence for an Unanticipated Relationship between Undifferentiated Pleomorphic Sarcoma and Embryonal Rhabdomyosarcoma by Rubin, Brian P., Nishijo, Koichi, Chen, Hung-I Harry, Yi, Xiaolan, Schuetze, David P., Pal, Ranadip, Prajapati, Suresh I., Abraham, Jinu, Arenkiel, Benjamin R., Chen, Qing-Rong, Davis, Sean, McCleish, Amanda T., Capecchi, Mario R., Michalek, Joel E., Zarzabal, Lee Ann, Khan, Javed, Yu, Zhongxin, Parham, David M., Barr, Frederic G., Meltzer, Paul S., Chen, Yidong, Keller, Charles

“…Embryonal rhabdomyosarcoma (eRMS) shows the most myodifferentiation among sarcomas, yet the precise cell of origin remains undefined. Using Ptch1, p53 and/or…”
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Evasion mechanisms to Igf1r inhibition in rhabdomyosarcoma by Abraham, Jinu, Prajapati, Suresh I, Nishijo, Koichi, Schaffer, Beverly S, Taniguchi, Eri, Kilcoyne, Aoife, McCleish, Amanda T, Nelon, Laura D, Giles, Francis G, Efstratiadis, Argiris, LeGallo, Robin D, Nowak, Brent M, Rubin, Brian P, Malempati, Suman, Keller, Charles

“…Inhibition of the insulin-like growth factor 1 receptor (Igf1r) is an approach being taken in clinical trials to overcome the dismal outcome for metastatic…”
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Credentialing a Preclinical Mouse Model of Alveolar Rhabdomyosarcoma by NISHIJO, Koichi, CHEN, Qing-Rong, ARONOW, Bruce J, BARR, Frederic G, LOR RANDALL, R, LADANYI, Marc, QUALMAN, Stephen J, RUBIN, Brian P, LEGALLO, Robin D, WANG, Chiayeng, KHAN, Javed, KELLER, Charles, LEI ZHANG, MCCLEISH, Amanda T, RODRIGUEZ, Andrea, MIN JUNG CHO, PRAJAPATI, Suresh I, GELFOND, Jonathan A. L, CHISHOLM, Gary B, MICHALEK, Joel E

“…The highly aggressive muscle cancer alveolar rhabdomyosarcoma (ARMS) is one of the most common soft tissue sarcoma of childhood, yet the outcome for the…”
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Immune competency of a hairless mouse strain for improved preclinical studies in genetically engineered mice by Schaffer, Beverly S, Grayson, Marcia H, Wortham, Joy M, Kubicek, Courtney B, McCleish, Amanda T, Prajapati, Suresh I, Nelon, Laura D, Brady, Michelle M, Jung, Inkyung, Hosoyama, Tohru, Sarro, Leslea M, Hanes, Martha A, Rubin, Brian P, Michalek, Joel E, Clifford, Charles B, Infante, Anthony J, Keller, Charles

“…Genetically engineered mouse models (GEMM) of cancer are of increasing value to preclinical therapeutics. Optical imaging is a cost-effective method of…”
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Lineage of origin in rhabdomyosarcoma informs pharmacological response by Abraham, Jinu, Nuñez-Álvarez, Yaiza, Hettmer, Simone, Carrió, Elvira, Chen, Hung-I Harry, Nishijo, Koichi, Huang, Elaine T, Prajapati, Suresh I, Walker, Robert L, Davis, Sean, Rebeles, Jennifer, Wiebush, Hunter, McCleish, Amanda T, Hampton, Sheila T, Bjornson, Christopher R R, Brack, Andrew S, Wagers, Amy J, Rando, Thomas A, Capecchi, Mario R, Marini, Frank C, Ehler, Benjamin R, Zarzabal, Lee Ann, Goros, Martin W, Michalek, Joel E, Meltzer, Paul S, Langenau, David M, LeGallo, Robin D, Mansoor, Atiya, Chen, Yidong, Suelves, Mònica, Rubin, Brian P, Keller, Charles

“…Lineage or cell of origin of cancers is often unknown and thus is not a consideration in therapeutic approaches. Alveolar rhabdomyosarcoma (aRMS) is an…”
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Biomarker system for studying muscle, stem cells, and cancer in vivo by Nishijo, Koichi, Hosoyama, Tohru, Bjornson, Christopher R.R, Schaffer, Beverly S, Prajapati, Suresh I, Bahadur, Ali N, Hansen, Mark S, Blandford, Mary C, McCleish, Amanda T, Rubin, Brian P, Epstein, Jonathan A, Rando, Thomas A, Capecchi, Mario R, Keller, Charles

“…Bioluminescent reporter genes are sensitive in situ tools for following disease progression in preclinical models, albeit they are subject to scattering and…”
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Bortezomib reverses a post-translational mechanism of tumorigenesis for patched1 haploinsufficiency in medulloblastoma by Taniguchi, Eri, Cho, Min Jung, Arenkiel, Benjamin R., Hansen, Mark S., Rivera, Omar J., McCleish, Amanda T., Qualman, Stephen J., Guttridge, Denis C., Scott, Matthew P., Capecchi, Mario R., Keller, Charles

“…Background Tumor initiation has been attributed to haploinsufficiency at a single locus for a large number of cancers. Patched1 (Ptc1) was one of the first…”
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Crimson carrier, A long-acting contrast agent for in vivo near-infrared imaging of injured and diseased muscle by Prajapati, Suresh I., Martinez, Carlo O., Abraham, Jinu, Mccleish, Amanda T., Michalek, Joel E., McManus, Linda M., Rubin, Brian P., Shireman, Paula K., Keller, Charles

“…The near‐infrared wavelengths (700–900 nm) are the most suitable optical window for light penetration and deep tissue imaging in small animals. Herein we…”
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