Search Results - "McClatchy, John"

Multiple pulse electroporation of lactic acid bacteria Lactococcus lactis and Lactobacillus casei by Welker, Dennis L., Coburn, Bryan M., McClatchy, John H., Broadbent, Jeff R.

“…Genetic manipulation of lactic acid bacteria is often difficult due to the inability to transform them with high efficiency. Multi-pulse electroporation offers…”
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Chronic IL1β Exposure Enhances Self-Renewal Ability and Myeloid Priming in TET2 Deficient Stem and Progenitor Cells by McClatchy, John, Strongantsev, Ruslan, Wolfe, Emily, Estabrook, Joseph, Lin, Hsin-Yun, M.Hosseini, Mona, Mohamed, Hisham, Agarwal, Anupriya

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Abstract 531: Disruption of a histone chaperone pathway delays inflammation-driven AML progression by Lin, Hsin-Yun, Mohammadhosseini, Mona, Villamor, Marina, McClatchy, John, Jeng, Sophia, Adey, Andrew, McWeeney, Shannon, Stracker, Travis, Agarwal, Anupriya

“…Background: Inflammation plays a crucial role in normal and malignant hematopoiesis. Patients with acute myeloid leukemia (AML) exhibit aberrant interleukin-1β…”
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Abrogation of a Histone Chaperone Pathway Mitigates Inflammation-Driven AML Progression by Lin, Hsin-Yun, M.Hosseini, Mona, Villamor, Marina, McClatchy, John, Jeng, Sophia, Eryildiz, Fatma, Adey, Andrew, McWeeney, Shannon K., Stracker, Travis, Agarwal, Anupriya

“…Background: Genetic heterogeneity makes clinical interventions challenging for acute myeloid leukemia (AML) patients. Identifying and targeting…”
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The TLK-ASF1 histone chaperone pathway plays a critical role in IL-1β–mediated AML progression by Lin, Hsin-Yun, Mohammadhosseini, Mona, McClatchy, John, Villamor-Payà, Marina, Jeng, Sophia, Bottomly, Daniel, Tsai, Chia-Feng, Posso, Camilo, Jacobson, Jeremy, Adey, Andrew, Gosline, Sara, Liu, Tao, McWeeney, Shannon, Stracker, Travis H., Agarwal, Anupriya

“…•TLK and ASF1 levels are elevated in patients with AML across genetic subtypes and upregulated by IL-1β–mediated inflammatory stress.•Targeting TLK2 or ASF1B…”
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3093 – CHRONIC IL1Β INDUCED STRESS DRIVES EXPANSION OF TET2 DEFICIENT PROGENITORS THROUGH ENHANCED SELF-RENEWAL ABILITY by McClatchy, John, Strogantsev, Ruslan, Eden, Christopher, Lin, hsin-Yun, Mohammadhosseini, mona, Monteblanco, Andrea, Goldman, Devorah, Cimmino, Luisa, Fleming, William, Mohammed, Hisham, Agarwal, Anupriya

“…Clonal hematopoiesis (CH) increases the risk for the development of myeloid malignancies. Inflammation plays a substantial role in leukemia progression;…”
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Targeting CCL2/CCR2 Signaling Overcomes MEK Inhibitor Resistance in Acute Myeloid Leukemia by Modak, Rucha V, de Oliveira Rebola, Katia G, McClatchy, John, Mohammadhosseini, Mona, Damnernsawad, Alisa, Kurtz, Stephen E, Eide, Christopher A, Wu, Guanming, Laderas, Ted, Nechiporuk, Tamilla, Gritsenko, Marina A, Hansen, Joshua R, Hutchinson, Chelsea, Gosline, Sara J C, Piehowski, Paul, Bottomly, Daniel, Short, Nicholas, Rodland, Karin, McWeeney, Shannon K, Tyner, Jeffrey W, Agarwal, Anupriya

“…Emerging evidence underscores the critical role of extrinsic factors within the microenvironment in protecting leukemia cells from therapeutic interventions,…”
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The TLK-ASF1 histone chaperone pathway plays a critical role in IL-1b-mediated AML progression by Lin, Hsin-Yun, M Hosseini, Mona, McClatchy, John, Villamor-Payà, Marina, Jeng, Sophia, Bottomly, Daniel, Tsai, Chia-Feng, Posso, Camilo, Jacobson, Jeremy, Adey, Andrew C, Gosline, Sara J C, Liu, Tao, McWeeney, Shannon K, Stracker, Travis H, Agarwal, Anupriya

“…Identifying and targeting microenvironment-driven pathways that are active across acute myeloid leukemia (AML) genetic subtypes should allow the development of…”
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PRICE DISCRIMINATION, MEETING COMPETITION AND PROMOTIONAL ALLOWANCES by McClatchy, John F

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