Search Results - "McClanahan, R. H."

Metabolism of [3H]pentosan polysulfate sodium (PPS) in healthy human volunteers by Simon, M., McClanahan, R. H., Shah, J. F., Repko, T., Modi, N. B.

“…Pentosan polysulfate sodium (PPS) is the active ingredient in ELMIRON®, a drug approved for the relief of bladder pain associated with interstitial cystitis…”
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The metabolism of the abortifacient terpene, (R)-(+)-pulegone, to a proximate toxin, menthofuran by Gordon, W P, Huitric, A C, Seth, C L, McClanahan, R H, Nelson, S D

“…(R)-(+)-Pulegone, the major monoterpene component of the abortifacient mint oil, pennyroyal oil, is metabolized by hepatic microsomal monooxygenases of the…”
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Metabolism of alachlor by rat and mouse liver and nasal turbinate tissues by Feng, P C, Wilson, A G, McClanahan, R H, Patanella, J E, Wratten, S J

“…The metabolism of alachlor was studied using in vitro incubations with microsomal fractions prepared from liver and nasal turbinates of rats and mice…”
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Investigations of mechanisms of reactive metabolite formation from (R)-(+)-pulegone by Nelson, S D, McClanahan, R H, Thomassen, D, Gordon, W P, Knebel, N

“…1. (R)-(+)-Pulegone is a monoterpene that is oxidized by cytochromes P-450 to reactive metabolites that initiate events in the pathogenesis of hepatotoxicity…”
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In Vitro Metabolism of Thiazopyr Plant Metabolites by Rat Liver Enzymes by Mcclanahan, R.H., Solsten, R.T., Feng, P.C.C., Logusch, E.W.

“…Thiazopyr [methyl 2-(difluoromethyl)-5-(4,5-dihydro-2-thiazolyl)-4-(2-methylpropyl)-6-(trifluoromethyl)-3-pyridinecarboxylate] is an experimental herbicide…”
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Reactive intermediates in the oxidation of menthofuran by cytochromes P-450 by Thomassen, David, Knebel, Norbert, Slattery, John T, McClanahan, Robert H, Nelson, Sidney D

“…Menthofuran, a naturally occurring hepatotoxin, is metabolically activated to chemically reactive intermediates that are capable of covalent binding to…”
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Biotransformation of Olivetol by Syncephalastrum racemosum by McClanahan, Robert H, Robertson, Larry W

“…A study of the biotransformation of olivetol by Syncephalastrum racemosum ATCC 18192 has led to the isolation of three metabolites, which were identified as…”
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Metabolic activation of tris(2,3-dibromopropyl)phosphate to reactive intermediates. I. Covalent binding and reactive metabolite formation in vitro by Pearson, P G, Omichinski, J G, McClanahan, R H, Søderlund, E J, Dybing, E, Nelson, S D

“…Analogs of tris(2,3-dibromopropyl)phosphate (Tris-BP) either labeled at specific positions with carbon-14, phosphorus-32, or oxygen-18 or dual-labeled with…”
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Metabolic activation of (R)-(+)-pulegone to a reactive enonal that covalently binds to mouse liver proteins by McClanahan, Robert H, Thomassen, David, Slattery, John T, Nelson, Sidney D

“…Pulegone, a naturally occurring hepatotoxin, is metabolically activated to chemically reactive intermediates that are capable of covalent binding to cellular…”
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Metabolic activation of tris(2,3-dibromopropyl)phosphate to reactive intermediates. II. Covalent binding, reactive metabolite formation, and differential metabolite-specific DNA damage in vivo by Pearson, P G, Omichinski, J G, Holme, J A, McClanahan, R H, Brunborg, G, Søderlund, E J, Dybing, E, Nelson, S D

“…Analogs of tris(2,3-dibromopropyl)phosphate (Tris-BP) either labeled at specific positions with carbon-14 and phosphorus-32 or dual-labeled with both deuterium…”
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Evidence for a cytochrome P-450-catalyzed allylic rearrangement with double-bond topomerization by McClanahan, Robert H, Huitric, Alain C, Pearson, Paul G, Desper, John C, Nelson, Sidney D

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Microbial Transformation of Olivetol by Fusarium roseum by McClanahan, Robert H, Robertson, Larry W

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Electric deregulation by McClanahan, R.H.

“…The author describes how the traditional electric utility environment could become a thing of the past as the industry restructures. The former order of the…”
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SCADA and IP: is network convergence really here? by McClanahan, McClanahan

“…This article has discussed improvements in cost/benefit and flexibility of both SCADA systems and corporate networks that can be achieved by combining the…”
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