Case of Thyrotoxic Periodic Paralysis in a Caucasian Male and Review of Literature

Objective. Thyrotoxic periodic paralysis (TPP), a known condition in Asian men, is becoming increasingly common in men from Western countries. Since suspicion for TPP as a differential in diagnosis is of utmost importance to avoid overcorrection of hypokalemia and other complications, we are reporti...

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Bibliographic Details
Published in:	Case Reports in Medicine Vol. 2014; no. 2014; pp. 250 - 254-055
Main Authors:	Waddadar, Jay, Nagireddy, Prathima, Munshi, Kartik, Nguyen, Tuyen, Syu, Stephanie, McCaw, Julie, Chhabra, Pankdeep, Katalenich, Bonnie, Parks, Rosemarie, Thethi, Tina, Larrazolo, Joshua
Format:	Journal Article
Language:	English
Published:	Cairo, Egypt Hindawi Limiteds 01-01-2014 Hindawi Publishing Corporation John Wiley & Sons, Inc Hindawi Limited
Subjects:	Care and treatment Case Report Case studies Causes of Complications and side effects Diagnosis Familial periodic paralysis Health sciences Hyperthyroidism Patients Tumors White people United States
Online Access:	Get full text
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Summary:	Objective. Thyrotoxic periodic paralysis (TPP), a known condition in Asian men, is becoming increasingly common in men from Western countries. Since suspicion for TPP as a differential in diagnosis is of utmost importance to avoid overcorrection of hypokalemia and other complications, we are reporting a case of TPP in a 25-year-old Caucasian male. Methods. The patient presented with intermittent lower extremity weakness after consumption of a large high-carbohydrate meal. Clinical examination revealed diffusely enlarged thyroid gland, no muscle power in lower extremities, tremors, and brisk deep tendon reflexes. Results. Clinical and laboratory findings were consistent with Graves’ disease and the patient had hypokalemia. The patient responded to potassium repletion and was treated with propylthiouracil and propranolol. After treatment with radioactive iodine, the patient developed postablative hypothyroidism for which he was treated with levothyroxine. Conclusion. Since this condition is overlooked by physicians in Western countries, we present a case of TPP in a Caucasian male thus showing the importance of consideration of TPP in Caucasians despite its rare occurrence and the need for prompt diagnosis to avoid the danger of hyperkalemia in management of the paralytic attack in TPP patients.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 Academic Editor: Ting Fan Leung
ISSN:	1687-9627 1687-9635
DOI:	10.1155/2014/314262