Search Results - "McCarthy, Douglas D"

Acquisition of a multifunctional IgA+ plasma cell phenotype in the gut by Fritz, Jörg H., Rojas, Olga Lucia, Simard, Nathalie, McCarthy, Douglas D., Hapfelmeier, Siegfried, Rubino, Stephen, Robertson, Susan J., Larijani, Mani, Gosselin, Jean, Ivanov, Ivaylo I., Martin, Alberto, Casellas, Rafael, Philpott, Dana J., Girardin, Stephen E., McCoy, Kathy D., Macpherson, Andrew J., Paige, Christopher J., Gommerman, Jennifer L.

“…IgA secreting plasma cells in the lamina propria are shown to be an important source of iNOS and TNF required to maintain the homeostatic balance between…”
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Mice overexpressing BAFF develop a commensal flora-dependent, IgA-associated nephropathy by McCarthy, Douglas D, Kujawa, Julie, Wilson, Cheryl, Papandile, Adrian, Poreci, Urjana, Porfilio, Elisa A, Ward, Lesley, Lawson, Melissa A E, Macpherson, Andrew J, McCoy, Kathy D, Pei, York, Novak, Lea, Lee, Jeannette Y, Julian, Bruce A, Novak, Jan, Ranger, Ann, Gommerman, Jennifer L, Browning, Jeffrey L

“…B cell activation factor of the TNF family (BAFF) is a potent B cell survival factor. BAFF overexpressing transgenic mice (BAFF-Tg mice) exhibit features of…”
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The lymphotoxin pathway: beyond lymph node development by McCarthy, Douglas D, Summers-Deluca, Leslie, Vu, Frances, Chiu, Sidney, Gao, Yunfei, Gommerman, Jennifer L

“…The first studies of mice deficient in lymphotoxin-alpha (LTalpha), LTbeta and LTbetaR revealed the seminal discovery that the LTbetaR signaling is critical…”
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BAFF induces a hyper-IgA syndrome in the intestinal lamina propria concomitant with IgA deposition in the kidney independent of LIGHT by McCarthy, Douglas D., Chiu, Sidney, Gao, Yunfei, Summers-deLuca, Leslie E., Gommerman, Jennifer L.

“…BAFF is a peripheral B cell survival factor and can mediate antibody (Ab) class switching. Over-expression of BAFF in mice results in B cell hyperplasia,…”
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Expression of lymphotoxin-αβ on antigen-specific T cells is required for DC function by Summers-deLuca, Leslie E., McCarthy, Douglas D., Cosovic, Bojana, Ward, Lesley A., Lo, Calvin C., Scheu, Stefanie, Pfeffer, Klaus, Gommerman, Jennifer L.

“…During an immune response, activated antigen (Ag)-specific T cells condition dendritic cells (DCs) to enhance DC function and survival within the inflamed…”
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Mice overexpressing BAFF develop a commensal flora–dependent, IgA-associated nephropathy by McCarthy, Douglas D., Kujawa, Julie, Wilson, Cheryl, Papandile, Adrian, Poreci, Urjana, Porfilio, Elisa A., Ward, Lesley, Lawson, Melissa A.E., Macpherson, Andrew J., McCoy, Kathy D., Pei, York, Novak, Lea, Lee, Jeannette Y., Julian, Bruce A., Novak, Jan, Ranger, Ann, Gommerman, Jennifer L., Browning, Jeffrey L.

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Acquisition of a multifunctional [IgA.sup.+] plasma cell phenotype in the gut by Fritz, Jorg H, Rojas, Olga Lucia, Simard, Nathalie, McCarthy, Douglas D, Hapfelmeier, Siegfried, Rubino, Stephen, Robertson, Susan J, Larijani, Mani, Gosselin, Jean, Ivanov, Ivaylo I, Martin, Alberto, Casellas, Rafael, Philpott, Dana J, Girardin, Stephen E, McCoy, Kathy D, Macpherson, Andrew J, Paige, Christopher J, Gommerman, Jennifer L

“…The largest mucosal surface in the body is in the gastrointestinal tract, a location that is heavily colonized by microbes that are normally harmless. A key…”
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Acquisition of a multifunctional IgA^sup +^ plasma cell phenotype in the gut by Fritz, Jörg H, Rojas, Olga Lucia, Simard, Nathalie, McCarthy, Douglas D, Hapfelmeier, Siegfried, Rubino, Stephen, Robertson, Susan J, Larijani, Mani, Gosselin, Jean, Ivanov, Ivaylo I, Martin, Alberto, Casellas, Rafael, Philpott, Dana J, Girardin, Stephen E, McCoy, Kathy D, Macpherson, Andrew J, Paige, Christopher J, Gommerman, Jennifer L

“…The largest mucosal surface in the body is in the gastrointestinal tract, a location that is heavily colonized by microbes that are normally harmless. A key…”
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Lymphotoxin is critically required for the presence of IgA‐promoting iNOS + DCs in the intestinal lamina propria by McCarthy, Douglas D, deLuca, Leslie Summers, Ward, Lesley, Gommerman, Jennifer L

“…Abstract only Lymphotoxin‐β receptor (LTβR) signaling is essential for IgA production in the intestinal lamina propria (LP) and it has been proposed that…”
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161 The role of lymphotoxin-beta-receptor signaling in dendritic cell function by deLuca, Leslie Summers, Gao, Yunfei, McCarthy, Douglas D., Ward, Lesley, Gommerman, Jennifer L.

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Expression of lymphotoxin‐αβ on antigen‐specific T cells is required for dendritic cell function by deLuca, Leslie Summers, McCarthy, Douglas D, Cosovic, Bojana, Ward, Lesley, Lo, Calvin, Scheu, Stefanie, Pfeffer, Klaus, Gommerman, Jennifer

“…Abstract only The lymphotoxin (LT) pathway has been shown to be important in T cell responses and DC homeostasis/activation. LTαβ is a TNF family member…”
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Expression of lymphotoxin-alphabeta on antigen-specific T cells is required for DC function by Summers-DeLuca, Leslie E, McCarthy, Douglas D, Cosovic, Bojana, Ward, Lesley A, Lo, Calvin C, Scheu, Stefanie, Pfeffer, Klaus, Gommerman, Jennifer L

“…During an immune response, activated antigen (Ag)-specific T cells condition dendritic cells (DCs) to enhance DC function and survival within the inflamed…”
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Expression of lymphotoxin- alpha {szligbeta} on antigen-specific T cells is required for DC function by Summers-deLuca, Leslie E, McCarthy, Douglas D, Cosovic, Bojana, Ward, Lesley A, Lo, Calvin C, Scheu, Stefanie, Pfeffer, Klaus, Gommerman, Jennifer L

“…During an immune response, activated antigen (Ag)-specific T cells condition dendritic cells (DCs) to enhance DC function and survival within the inflamed…”
Get full text