Search Results - "McCarter, Martin. D."

Virtual memory T cells develop and mediate bystander protective immunity in an IL-15-dependent manner by White, Jason T., Cross, Eric W., Burchill, Matthew A., Danhorn, Thomas, McCarter, Martin D., Rosen, Hugo R., O’Connor, Brian, Kedl, Ross M.

“…Virtual memory cells (VM) are an antigen-specific, memory phenotype CD8 T-cell subset found in lymphoreplete, unchallenged mice. Previous studies indicated…”
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Characteristics of 10-Year Survivors of Pancreatic Ductal Adenocarcinoma by Paniccia, Alessandro, Hosokawa, Patrick, Henderson, William, Schulick, Richard D, Edil, Barish H, McCarter, Martin D, Gajdos, Csaba

“…To our knowledge, this study reports on the largest cohort of long-term survivors (LTSs) (≥10 years) following a diagnosis of pancreatic ductal adenocarcinoma…”
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ALDH1A Isozymes are Markers of Human Melanoma Stem Cells and Potential Therapeutic Targets by Luo, Yuchun, Dallaglio, Katiuscia, Chen, Ying, Robinson, William A., Robinson, Steven E., McCarter, Martin D., Wang, Jianbin, Gonzalez, Rene, Thompson, David C., Norris, David A., Roop, Dennis R., Vasiliou, Vasilis, Fujita, Mayumi

“…Although the concept of cancer stem cells (CSCs) is well‐accepted for many tumors, the existence of such cells in human melanoma has been the subject of…”
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Palliative Management of Gastric and Esophageal Cancer by Halpern, Alison L., MD, McCarter, Martin D., MD

“…In patients with advanced esophageal or gastric cancer, it is highly likely that palliation of symptoms will become a focus of treatment. Dysphagia and…”
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Impact of Facility Type and Surgical Volume on 10-Year Survival in Patients undergoing Hepatic Resection for Hepatocellular Carcinoma by Chapman, Brandon C., MD, Paniccia, Alessandro, MD, Hosokawa, Patrick W., BS, Henderson, William G., PhD, Overbey, Douglas M., MD, Messersmith, Wells, MD, McCarter, Martin D., MD, FACS, Gleisner, Ana, MD, PhD, Edil, Barish H., MD, FACS, Schulick, Richard D., MD, FACS, Gajdos, Csaba, MD, FACS

“…Abstract Background Previous studies have demonstrated improved in-hospital mortality following hepatic resection for hepatocellular carcinoma (HCC) at…”
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Diverse Intestinal Bacteria Contain Putative Zwitterionic Capsular Polysaccharides with Anti-inflammatory Properties by Neff, C. Preston, Rhodes, Matthew E., Arnolds, Kathleen L., Collins, Colm B., Donnelly, Jody, Nusbacher, Nichole, Jedlicka, Paul, Schneider, Jennifer M., McCarter, Martin D., Shaffer, Michael, Mazmanian, Sarkis K., Palmer, Brent E., Lozupone, Catherine A.

“…Zwitterionic capsular polysaccharides (ZPSs) are bacterial products that modulate T cells, including inducing anti-inflammatory IL-10-secreting T regulatory…”
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Adjuvant imatinib mesylate after resection of localised, primary gastrointestinal stromal tumour: a randomised, double-blind, placebo-controlled trial by DeMatteo, Ronald P, Prof, Ballman, Karla V, PhD, Antonescu, Cristina R, MD, Maki, Robert G, MD, Pisters, Peter WT, Prof, Demetri, George D, MD, Blackstein, Martin E, MD, Blanke, Charles D, Prof, von Mehren, Margaret, MD, Brennan, Murray F, Prof, Patel, Shreyaskumar, Prof, McCarter, Martin D, MD, Polikoff, Jonathan A, MD, Tan, Benjamin R, MD, Owzar, Kouros, PhD

“…Summary Background Gastrointestinal stromal tumour is the most common sarcoma of the intestinal tract. Imatinib mesylate is a small molecule that inhibits…”
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Secretory Phospholipase A2 IIa Mediates Expression of Growth Factor Receptors in Esophageal Adenocarcinoma by Halpern, Alison L., Kohtz, Patrick D., White, Allana M., Houk, Anna K., Rehring, Jacob F., Hanson, Levent, McCarter, Martin. D., Joshi, Molishree, Meng, Xianzhong, Fullerton, David A., Weyant, Michael J.

“…Background Receptor tyrosine kinases of the epidermal growth factor receptor (EGFR) family such as human epidermal receptor-2 (HER2) are involved in the…”
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Effect of Body Mass Index on Short-Term Outcomes after Colectomy for Cancer by Merkow, Ryan P., MD, Bilimoria, Karl Y., MD, MS, McCarter, Martin D., MD, FACS, Bentrem, David J., MD, FACS

“…Background Obesity is associated with an increased risk of postoperative complications after colectomy for cancer, but it is unclear which specific…”
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IL-6 and IL-8 Are Linked With Myeloid-Derived Suppressor Cell Accumulation and Correlate With Poor Clinical Outcomes in Melanoma Patients by Tobin, Richard P., Jordan, Kimberly R., Kapoor, Puja, Spongberg, Eric, Davis, Dana, Vorwald, Victoria M., Couts, Kasey L., Gao, Dexiang, Smith, Derek E., Borgers, Jessica S. W., Robinson, Steven, Amato, Carol, Gonzalez, Rene, Lewis, Karl D., Robinson, William A., Borges, Virginia F., McCarter, Martin D.

“…We sought to identify tumor-secreted factors that altered the frequency of MDSCs and correlated with clinical outcomes in advanced melanoma patients. We…”
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Whole-exome sequencing identifies recurrent SF3B1 R625 mutation and comutation of NF1 and KIT in mucosal melanoma by Hintzsche, Jennifer D, Gorden, Nicholas T, Amato, Carol M, Kim, Jihye, Wuensch, Kelsey E, Robinson, Steven E, Applegate, Allison J, Couts, Kasey L, Medina, Theresa M, Wells, Keith R, Wisell, Joshua A, McCarter, Martin D, Box, Neil F, Shellman, Yiqun G, Gonzalez, Rene C, Lewis, Karl D, Tentler, John J, Tan, Aik Choon, Robinson, William A

“…Mucosal melanomas are a rare subtype of melanoma, arising in mucosal tissues, which have a very poor prognosis due to the lack of effective targeted therapies…”
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GPR182 limits antitumor immunity via chemokine scavenging in mouse melanoma models by Torphy, Robert J., Sun, Yi, Lin, Ronggui, Caffrey-Carr, Alayna, Fujiwara, Yuki, Ho, Felix, Miller, Emily N., McCarter, Martin D., Lyons, Traci R., Schulick, Richard D., Kedl, Ross M., Zhu, Yuwen

“…For many solid tumors, immune checkpoint blockade therapy has become first line treatment, yet a large proportion of patients with immunologically cold tumors…”
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Microscopically Positive Margins for Primary Gastrointestinal Stromal Tumors: Analysis of Risk Factors and Tumor Recurrence by McCarter, Martin D., MD, FACS, Antonescu, Cristina R., MD, Ballman, Karla V., PhD, Maki, Robert G., MD, PhD, Pisters, Peter W.T., MD, FACS, Demetri, George D., MD, Blanke, Charles D., MD, von Mehren, Margaret, MD, Brennan, Murray F., MD, FACS, McCall, Linda, MS, Ota, David M., MD, FACS, DeMatteo, Ronald P., MD, FACS

“…Background Little is known about the outcomes of patients with microscopically positive (R1) resections for primary gastrointestinal stromal tumors (GIST)…”
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Interferon-α Subtypes in an Ex Vivo Model of Acute HIV-1 Infection: Expression, Potency and Effector Mechanisms by Harper, Michael S, Guo, Kejun, Gibbert, Kathrin, Lee, Eric J, Dillon, Stephanie M, Barrett, Bradley S, McCarter, Martin D, Hasenkrug, Kim J, Dittmer, Ulf, Wilson, Cara C, Santiago, Mario L

“…HIV-1 is transmitted primarily across mucosal surfaces and rapidly spreads within the intestinal mucosa during acute infection. The type I interferons (IFNs)…”
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Commensal and Pathogenic Bacteria Indirectly Induce IL-22 but Not IFNγ Production From Human Colonic ILC3s via Multiple Mechanisms by Castleman, Moriah J, Dillon, Stephanie M, Purba, Christine M, Cogswell, Andrew C, Kibbie, Jon J, McCarter, Martin D, Santiago, Mario L, Barker, Edward, Wilson, Cara C

“…Innate lymphoid cells (ILCs) are a diverse family of cells that play critical roles in mucosal immunity. One subset of the ILC family, Group 3 ILCs (ILC3s),…”
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MAIT Cells: Partners or Enemies in Cancer Immunotherapy? by Cogswell, Dasha T, Gapin, Laurent, Tobin, Heather M, McCarter, Martin D, Tobin, Richard P

“…A recent boom in mucosal-associated invariant T (MAIT) cell research has identified relationships between MAIT cell abundance, function, and clinical outcomes…”
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Prospective Evaluation of a Universally Applied Laparoscopic Gastric Ischemic Preconditioning Protocol Prior to Esophagectomy with Comparison with Historical Controls by Gergen, Anna K., Stuart, Christina M., Byers, Sara, Vigneshwar, Navin, Madsen, Helen, Johnson, Jocelyn, Oase, Kristen, Garduno, Nicole, Marsh, Megan, Pratap, Akshay, Mitchell, John D., David, Elizabeth A., Randhawa, Simran, Meguid, Robert A., McCarter, Martin D., Stewart, Camille L.

“…Background Anastomotic leak after esophagectomy is associated with significant morbidity and mortality. Our institution began performing laparoscopic gastric…”
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Follicular regulatory T cells eliminate HIV-1-infected follicular helper T cells in an IL-2 concentration dependent manner by Ollerton, Matthew T, Folkvord, Joy M, La Mantia, Andriana, Parry, David A, Meditz, Amie L, McCarter, Martin D, D'Aquila, Richard T, Connick, Elizabeth

“…Follicular helper CD4 T cells (TFH) are highly permissive to HIV and major foci of virus expression in both untreated and treated infection. Follicular…”
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MCL1 inhibition targets Myeloid Derived Suppressors Cells, promotes antitumor immunity and enhances the efficacy of immune checkpoint blockade by Mukherjee, Nabanita, Katsnelson, Elizabeth, Brunetti, Tonya M., Michel, Kylie, Couts, Kasey L., Lambert, Karoline A., Robinson, William A., McCarter, Martin D., Norris, David A., Tobin, Richard P., Shellman, Yiqun G.

“…Immune checkpoint inhibitors (ICIs) are now the first-line treatment for patients with advanced melanoma. Despite promising clinical results, many patients…”
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Fecal Microbiota Composition Drives Immune Activation in HIV-infected Individuals by Neff, Charles Preston, Krueger, Owen, Xiong, Kathy, Arif, Sabrina, Nusbacher, Nichole, Schneider, Jennifer M., Cunningham, Annie W., Armstrong, Abigail, Li, Sam, McCarter, Martin D., Campbell, Thomas B., Lozupone, Catherine A., Palmer, Brent E.

“…The inflammatory properties of the enteric microbiota of Human Immunodeficiency Virus (HIV)-infected individuals are of considerable interest because of strong…”
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