Search Results - "McCarten, J Riley"

Age‐related differences in macromolecular resonances observed in ultra‐short‐TE STEAM MR spectra at 7T by Genovese, Guglielmo, Terpstra, Melissa, Filip, Pavel, Mangia, Silvia, McCarten, J. Riley, Hemmy, Laura S., Marjańska, Małgorzata

“…Purpose To understand how macromolecular content varies in the human brain with age in a large cohort of healthy subjects. Methods In‐vivo 1H‐MR spectra were…”
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Distinctive Neurochemistry in Alzheimer's Disease via 7 T In Vivo Magnetic Resonance Spectroscopy by Marjańska, Małgorzata, McCarten, J Riley, Hodges, James S, Hemmy, Laura S, Terpstra, Melissa

“…This study's objective was to increase understanding of biological mechanisms underlying clinical Alzheimer's disease (AD) by noninvasively measuring an…”
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Scyllo‐inositol: Transverse relaxation time constant at 3 T and concentration changes associated with aging and alcohol use by Deelchand, Dinesh K., Eberly, Lynn E., McCarten, J. Riley, Hemmy, Laura S., Auerbach, Edward J., Marjańska, Małgorzata

“…The goals of this study were to measure the apparent transverse relaxation time constant, T2, of scyllo‐inositol (sIns) in young and older healthy adults'…”
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Screening for Cognitive Impairment in an Elderly Veteran Population: Acceptability and Results Using Different Versions of the Mini-Cog by McCarten, J. Riley, Anderson, Pauline, Kuskowski, Michael A., McPherson, Susan E., Borson, Soo

“…OBJECTIVES: To assess the feasibility of cognitive screening in older veterans presenting for routine primary care. DESIGN: Quality improvement initiative…”
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Improving dementia care: The role of screening and detection of cognitive impairment by Borson, Soo, Frank, Lori, Bayley, Peter J, Boustani, Malaz, Dean, Marge, Lin, Pei-Jung, McCarten, J. Riley, Morris, John C, Salmon, David P, Schmitt, Frederick A, Stefanacci, Richard G, Mendiondo, Marta S, Peschin, Susan, Hall, Eric J, Fillit, Howard, Ashford, J. Wesson

“…Abstract The value of screening for cognitive impairment, including dementia and Alzheimer's disease, has been debated for decades. Recent research on causes…”
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Clinical Evaluation of Early Cognitive Symptoms by McCarten, J. Riley, MD

“…The etiology of cognitive impairment in older adults is almost always a clinical diagnosis without definitive biomarkers. The clinical evaluation, therefore,…”
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Risk Stratification Using Cerebrospinal Fluid Biomarkers in Patients with Mild Cognitive Impairment: An Exploratory Analysis by Michaud, Tzeyu L, Kane, Robert L, McCarten, J Riley, Gaugler, Joseph E, Nyman, John A, Kuntz, Karen M

“…Cerebrospinal fluid (CSF) biomarkers can distinguish Alzheimer's disease (AD) patients from normal controls; however, their interpretation and potential for…”
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Physical Activity Interventions in Preventing Cognitive Decline and Alzheimer-Type Dementia: A Systematic Review by Brasure, Michelle, Desai, Priyanka, Davila, Heather, Nelson, Victoria A, Calvert, Collin, Jutkowitz, Eric, Butler, Mary, Fink, Howard A, Ratner, Edward, Hemmy, Laura S, McCarten, J Riley, Barclay, Terry R, Kane, Robert L

“…The prevalence of cognitive impairment and dementia is expected to increase dramatically as the population ages, creating burdens on families and health care…”
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Does Cognitive Training Prevent Cognitive Decline?: A Systematic Review by Butler, Mary, McCreedy, Ellen, Nelson, Victoria A, Desai, Priyanka, Ratner, Edward, Fink, Howard A, Hemmy, Laura S, McCarten, J Riley, Barclay, Terry R, Brasure, Michelle, Davila, Heather, Kane, Robert L

“…Structured activities to stimulate brain function-that is, cognitive training exercises-are promoted to slow or prevent cognitive decline, including dementia,…”
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Pharmacologic Interventions to Prevent Cognitive Decline, Mild Cognitive Impairment, and Clinical Alzheimer-Type Dementia: A Systematic Review by Fink, Howard A, Jutkowitz, Eric, McCarten, J Riley, Hemmy, Laura S, Butler, Mary, Davila, Heather, Ratner, Edward, Calvert, Collin, Barclay, Terry R, Brasure, Michelle, Nelson, Victoria A, Kane, Robert L

“…Optimal treatment to prevent or delay cognitive decline, mild cognitive impairment (MCI), or dementia is uncertain. To summarize current evidence on the…”
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Over-the-Counter Supplement Interventions to Prevent Cognitive Decline, Mild Cognitive Impairment, and Clinical Alzheimer-Type Dementia: A Systematic Review by Butler, Mary, Nelson, Victoria A, Davila, Heather, Ratner, Edward, Fink, Howard A, Hemmy, Laura S, McCarten, J Riley, Barclay, Terry R, Brasure, Michelle, Kane, Robert L

“…Optimal interventions to prevent or delay cognitive decline, mild cognitive impairment (MCI), or dementia are uncertain. To summarize the evidence on efficacy…”
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Effect of Vitamin E and Memantine on Functional Decline in Alzheimer Disease: The TEAM-AD VA Cooperative Randomized Trial by Dysken, Maurice W, Sano, Mary, Asthana, Sanjay, Vertrees, Julia E, Pallaki, Muralidhar, Llorente, Maria, Love, Susan, Schellenberg, Gerard D, McCarten, J. Riley, Malphurs, Julie, Prieto, Susana, Chen, Peijun, Loreck, David J, Trapp, George, Bakshi, Rajbir S, Mintzer, Jacobo E, Heidebrink, Judith L, Vidal-Cardona, Ana, Arroyo, Lillian M, Cruz, Angel R, Zachariah, Sally, Kowall, Neil W, Chopra, Mohit P, Craft, Suzanne, Thielke, Stephen, Turvey, Carolyn L, Woodman, Catherine, Monnell, Kimberly A, Gordon, Kimberly, Tomaska, Julie, Segal, Yoav, Peduzzi, Peter N, Guarino, Peter D

“…IMPORTANCE Although vitamin E and memantine have been shown to have beneficial effects in moderately severe Alzheimer disease (AD), evidence is limited in mild…”
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Accuracy of Biomarker Testing for Neuropathologically Defined Alzheimer Disease in Older Adults With Dementia: A Systematic Review by Fink, Howard A., Linskens, Eric J., Silverman, Pombie C., McCarten, J. Riley, Hemmy, Laura S., Ouellette, Jeannine M., Greer, Nancy L., Wilt, Timothy J., Butler, Mary

“…Background: Biomarker accuracy for Alzheimer disease (AD) is uncertain. Purpose: To summarize evidence on biomarker accuracy for classifying AD in older adults…”
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Benefits and Harms of Prescription Drugs and Supplements for Treatment of Clinical Alzheimer-Type Dementia: A Systematic Review and Meta-analysis by Fink, Howard A., Linskens, Eric J., MacDonald, Roderick, Silverman, Pombie C., McCarten, J. Riley, Talley, Kristine M.C., Forte, Mary L., Desai, Priyanka J., Nelson, Victoria A., Miller, Margaret A., Hemmy, Laura S., Brasure, Michelle, Taylor, Brent C., Ng, Weiwen, Ouellette, Jeannine M., Sheets, Kerry M., Wilt, Timothy J., Butler, Mary

“…Background: Effects of drug treatment of clinical Alzheimer-type dementia (CATD) are uncertain. Purpose: To summarize evidence on the effects of prescription…”
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Changes in the intracellular microenvironment in the aging human brain by Deelchand, Dinesh K., McCarten, J. Riley, Hemmy, Laura S., Auerbach, Edward J., Eberly, Lynn E., Marjańska, Małgorzata

“…Normal brain aging is associated with changes occurring at all levels. This study investigates age-related differences in the brain intracellular…”
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Altered macromolecular pattern and content in the aging human brain by Marjańska, Małgorzata, Deelchand, Dinesh K., Hodges, James S., McCarten, J. Riley, Hemmy, Laura S., Grant, Andrea, Terpstra, Melissa

“…The resonances originating from proteins underlie those of metabolites in brain 1H nuclear magnetic resonance (NMR) spectra. These resonances have different…”
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Predictive Value of the Cognitive Performance Test (CPT) for Staging Function and Fitness to Drive in People With Neurocognitive Disorders by Burns, Theressa, Lawler, Katie, Lawler, David, McCarten, J Riley, Kuskowski, Michael

“…The Cognitive Performance Test (CPT) is a standardized occupational therapy assessment that examines cognitive integration with functioning in an instrumental…”
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Intermediate- and Long-Term Cognitive Outcomes After Cardiovascular Procedures in Older Adults: A Systematic Review by Fink, Howard A, Hemmy, Laura S, MacDonald, Roderick, Carlyle, Maureen H, Olson, Carin M, Dysken, Maurice W, McCarten, J Riley, Kane, Robert L, Garcia, Santiago A, Rutks, Indulis R, Ouellette, Jeannine, Wilt, Timothy J

“…Risks for intermediate- and long-term cognitive impairment after cardiovascular procedures in older adults are poorly understood. To summarize evidence about…”
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Region-specific aging of the human brain as evidenced by neurochemical profiles measured noninvasively in the posterior cingulate cortex and the occipital lobe using 1H magnetic resonance spectroscopy at 7 T by Marjańska, Małgorzata, McCarten, J. Riley, Hodges, James, Hemmy, Laura S., Grant, Andrea, Deelchand, Dinesh K., Terpstra, Melissa

“…[Display omitted] •Age-associated neurochemical concentration differences were measured non-invasively.•Differences in 8 out of 14 neurochemicals were…”
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Region-specific aging of the human brain as evidenced by neurochemical profiles measured noninvasively in the posterior cingulate cortex and the occipital lobe using 1 H magnetic resonance spectroscopy at 7 T by Marjańska, Małgorzata, McCarten, J Riley, Hodges, James, Hemmy, Laura S, Grant, Andrea, Deelchand, Dinesh K, Terpstra, Melissa

“…The concentrations of fourteen neurochemicals associated with metabolism, neurotransmission, antioxidant capacity, and cellular structure were measured…”
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