Search Results - "McCarron, J. G."

The phospholipase C inhibitor U‐73122 inhibits Ca2+ release from the intracellular sarcoplasmic reticulum Ca2+ store by inhibiting Ca2+ pumps in smooth muscle by MacMillan, D, McCarron, JG

“…Background and purpose:  The sarcoplasmic reticulum (SR) releases Ca2+ via inositol 1,4,5‐trisphosphate receptors (IP3R) in response to IP3‐generating…”
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Regulation by FK506 and rapamycin of Ca2+ release from the sarcoplasmic reticulum in vascular smooth muscle: the role of FK506 binding proteins and mTOR by MacMillan, D, McCarron, JG

“…Background and purpose:  The sarcoplasmic reticulum (SR), regulates the cytoplasmic Ca2+ concentration ([Ca2+]cyto) in vascular smooth muscle. Release from the…”
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The phospholipase C inhibitor U-73122 inhibits Ca(2+) release from the intracellular sarcoplasmic reticulum Ca(2+) store by inhibiting Ca(2+) pumps in smooth muscle by Macmillan, D, McCarron, J G

“…The sarcoplasmic reticulum (SR) releases Ca(2+) via inositol 1,4,5-trisphosphate receptors (IP(3)R) in response to IP(3)-generating agonists. Ca(2+) release…”
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Inward rectifier K+ currents in smooth muscle cells from rat resistance-sized cerebral arteries by Quayle, J M, McCarron, J G, Brayden, J E, Nelson, M T

“…Inward rectifier K+ channels have been implicated in the control of membrane potential and external K(+)-induced dilations of small cerebral arteries. In the…”
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Regulation of the cytosolic Ca2+ concentration by Ca2+ stores in single smooth muscle cells from rat cerebral arteries by Kamishima, T., McCarron, J. G.

“…1. There is no general agreement on the presence or role of Ca(2+)-induced Ca2+ release in smooth muscle. In this paper, Ca(2+)-induced Ca2+ release has been…”
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Myogenic contraction by modulation of voltage-dependent calcium currents in isolated rat cerebral arteries by McCarron, J G, Crichton, C A, Langton, P D, MacKenzie, A, Smith, G L

“…1. Tissue blood flow and blood pressure are regulated by the spontaneous, myogenic, contraction developed by resistance arteries. However, the cellular…”
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Potassium dilates rat cerebral arteries by two independent mechanisms by McCarron, J G, Halpern, W

“…Cerebral blood flow is regulated by brain metabolism, and there is evidence to suggest that changes in extracellular potassium concentration are important in…”
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ATP inhibits Ins(1,4,5)P3-evoked Ca2+ release in smooth muscle via P2Y1 receptors by MacMillan, D, Kennedy, C, McCarron, J G

“…Adenosine 5'-triphosphate (ATP) mediates a variety of biological functions following nerve-evoked release, via activation of either G-protein-coupled P2Y- or…”
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Depolarization-evoked increases in cytosolic calcium concentration in isolated smooth muscle cells of rat portal vein by Kamishima, T, McCarron, J G

“…1. Ca2+ current through voltage-dependent Ca2+ channels (ICa) and intracellular free Ca2+ concentration ([Ca2+]i) were measured simultaneously in rat portal…”
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Striatal neurones show sustained recovery from severe hypoglycaemic insult by McDermott, C. J., Bradley, K. N., McCarron, J. G., Palmer, A. M., Morris, B. J.

“…Glucose deprivation provides a reliable model to investigate cellular responses to metabolic dysfunction, and is reportedly associated with permanent cell…”
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The temporal profile of calcium transients in voltage clamped gastric myocytes from Bufo marinus by McGeown, J G, Drummond, R M, McCarron, J G, Fay, F S

“…1. Decay in intracellular calcium concentration ([Ca2+]i) was recorded following step depolarizations in voltage clamped gastric myocytes from Bufo marinus. 2…”
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Impaired Potassium-Induced Dilation in Hypertensive Rat Cerebral Arteries Does Not Reflect Altered Na+,K+-ATPase Dilation by McCarron, J G, Halpern, W

“…We have recently demonstrated that K-induced dilation of cerebral resistance-sized vessels has two independent components, only one of which seemed sodium pump…”
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Calcium-calmodulin-dependent mechanisms accelerate calcium decay in gastric myocytes from Bufo marinus by McGeown, J. G., McCarron, J. G., Drummond, R. M., Fay, F. S.

“…[Ca 2+ ] i was recorded in voltage-clamped gastric myocytes from Bufo marinus . Repolarization to -110 mV following a 300 ms depolarization to +10 mV led to…”
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Cromakalim and pinacidil dilate small mesenteric arteries but not small cerebral arteries by McCarron, J G, Quayle, J M, Halpern, W, Nelson, M T

“…Small elevations in external K+ hyperpolarize and dilate small cerebral arteries. The hyperpolarization and dilation to K+ are blocked by barium (less than 0.1…”
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Modulation of high- and low-voltage-activated calcium currents in smooth muscle by calcium by McCarron, J G, McGeown, J G, Walsh, Jr, J V, Fay, F S

“…Ca2+ currents (ICa) and cytoplasmic Ca2+ concentration ([Ca2+]c) were measured in isolated gastric myocytes from Bufo marinus using whole cell voltage clamp…”
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Single calcium channels in resistance-sized cerebral arteries from rats by Quayle, J M, McCarron, J G, Asbury, J R, Nelson, M T

“…Unitary currents through single calcium channels were measured from cell-attached patches on smooth muscle cells isolated from resistance-sized branches of…”
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Functionally Separate Intracellular Ca2+ Stores in Smooth Muscle by Flynn, Elaine R.M., Bradley, Karen N., Muir, Thomas C., McCarron, John G.

“…In smooth muscle, release via the inositol 1,4,5-trisphosphate (Ins(1,4,5)P3R) and ryanodine receptors (RyR) on the sarcoplasmic reticulum (SR) controls…”
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Release of [3H]‐noradrenaline from the sympathetic nerves to bovine mesenteric lymphatic vessels and its modification by α‐agonists and antagonists by Allen, J.M., McCarron, J.G., McHale, N.G., Thornbury, K.D.

“…1 Isolated segments of bovine mesenteric lymphatic vessels were loaded with [3H]‐noradrenaline and its efflux in response to field stimulation examined…”
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Sarcolemma agonist-induced interactions between InsP3 and ryanodine receptors in Ca2+ oscillations and waves in smooth muscle by McCarron, J G, Bradley, K N, MacMillan, D, Muir, T C

“…Smooth muscle cells respond to InsP(3)-generating (sarcolemma-acting) neurotransmitters and hormones by releasing Ca(2+) from the internal store. However, the…”
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Transient excitatory responses to sustained stimulation of intramural nerves in isolated bovine lymphatic vessels by McHale, N G, Allen, J M, McCarron, J G

“…Spontaneous isometric contractions were measured in 2 cm segments of bovine mesenteric lymphatics. Field stimulation at 4 Hz was applied for a 20 min period…”
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