Search Results - "McCann, MT"
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Substrate-Induced Conformational Change in a Trimeric Ornithine Transcarbamoylase
Published in Proceedings of the National Academy of Sciences - PNAS (02-09-1997)“…The crystal structure of Escherichia coli ornithine transcarbamoylase (OTCase, EC 2.1.3.3) complexed with the bisubstrate analog N-(phosphonacetyl)-L-ornithine…”
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Hepatic glutamine synthetase deficiency in fatal hyperammonemia after lung transplantation
Published in Annals of internal medicine (15-09-1997)“…The cause of severe acquired hyperammonemia, an uncommon but often fatal complication of organ transplantation and chemotherapy for cancer, is obscure. To test…”
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Expression, purification, and characterization of recombinant human glutamine synthetase
Published in Biochemical journal (15-11-1997)“…A bacterial expression system has been engineered for human glutamine synthetase (EC 6.3.1.2) that produces approximately 60 mg of enzyme (20% of the bacterial…”
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Intravenous infusion of 4-AP in chronic spinal cord injured subjects
Published in Spinal cord (01-01-2000)“…A prospective double blind cross over trial of intravenous 4-Aminopyridine (4-AP). To determine the efficacy of this drug in the treatment of spinal cord…”
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Expression, purification and kinetic characterization of wild-type human ornithine transcarbamylase and a recurrent mutant that produces 'late onset' hyperammonaemia
Published in Biochemical journal (01-03-1997)“…Ornithine Transcarbamylase Deficiency, an X-linked disorder, is the most common cause of inherited urea cycle disorders. Approx. 90 mutations that produce…”
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Quantification of orotic acid in dried filter-paper urine samples by stable isotope dilution
Published in Clinical chemistry (Baltimore, Md.) (01-05-1995)“…A rapid, sensitive, and specific method for quantification of orotic acid from dried filter-paper urine samples is described. The method involves stable…”
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Methylmalonic acid quantification by stable isotope dilution gas chromatography-mass spectrometry from filter paper urine samples
Published in Clinical chemistry (Baltimore, Md.) (01-06-1996)“…A specific method for quantification of methylmalonic acid (MMA) from urine samples dried onto filter paper is described. The method involves stable isotope…”
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‘Late Onset’ Ornithine Transcarbamylase Deficiency: Function of Three Purified Recombinant Mutant Enzymes
Published in Human molecular genetics (01-06-1997)“…Although many mutations in the ornithine transcarbamylase gene have been correlated with ‘late onset’ of hyperammonemia in patients, the effects of these…”
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Enhanced production of arginine and urea by genetically engineered Escherichia coli K-12 strains
Published in Applied and Environmental Microbiology (01-01-1997)“…Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon…”
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Screening for neuroblastoma at 3 weeks of age: methods and preliminary results from the Quebec Neuroblastoma Screening Project
Published in Pediatrics (Evanston) (01-11-1990)“…A large neuroblastoma screening study was recently started in the province of Quebec, Canada. This project, a collaboration between the Quebec Network for…”
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Screening newborns for multiple organic acidurias in dried filter paper urine samples : method development
Published in Pediatric research (01-10-1991)“…Screening urine for inherited and acquired organic acidurias in newborns has the potential of preventing severe disease, mental retardation, and death. A…”
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Spacing in Acorn Woodpeckers
Published in Ecology (Durham) (01-02-1985)“…Territorial behavior in Melanerpes formicivorus is discussed…”
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Screening urine of 3-week-old newborns: transient methylmalonic and hydroxyphenyllactic aciduria
Published in Biochemical medicine and metabolic biology (01-08-1992)“…Urinary methylmalonic acid (MMA) and 4-hydroxyphenyllactic acid (HPL) have been determined in 3345 and 2498 3-week-old newborns, respectively. Urine was…”
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A contribution to the germination ecology of Floerkea proserpinacoides (Limnanthaceae)
Published in Botanical gazette (Chicago, Ill.) (01-12-1988)“…Seeds of the spring ephemeral Floerkea proserpinacoides (Limnanthaceae) were dormant at maturity in mid to late May. Fresh seeds sown on soil in a…”
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