Search Results - "McCalmont, Aaron S"

Mechanochemistry Can Reduce Life Cycle Environmental Impacts of Manufacturing Active Pharmaceutical Ingredients by Galant, Or, Cerfeda, Giacomo, McCalmont, Aaron S, James, Stuart L, Porcheddu, Andrea, Delogu, Francesco, Crawford, Deborah E, Colacino, Evelina, Spatari, Sabrina

“…The scale-up of mechanochemical methods could play a transformative role in making manufacturing processes in the pharmaceutical industry greener by…”
Get full text

Solvent-Free, Continuous Synthesis of Hydrazone-Based Active Pharmaceutical Ingredients by Twin-Screw Extrusion by Crawford, Deborah E, Porcheddu, Andrea, McCalmont, Aaron S, Delogu, Francesco, James, Stuart L, Colacino, Evelina

“…Twin-screw extrusion (TSE) was used to synthesize hydantoin-based active pharmaceutical ingredients (APIs) such as nitrofurantoin and dantrolene, employing…”
Get full text

Cytotoxicity of Mechanochemically Prepared Cu(II) Complexes by McCalmont, Aaron S, Ruiz, Amalia, Lagunas, M. Cristina, Al-Jamal, Wafa T, Crawford, Deborah E

“…Despite evidence that mechanochemistry has the potential to be a revolutionary manufacturing technique, the Pharma industry is still reluctant to introduce…”
Get full text

LCA as a Tool to Detect Environmental “Hot Spots” in Early-Stage Mechanochemical Synthesis of Organic Dyes by Galant, Or, Aborome, Aseel, McCalmont, Aaron S., James, Stuart L., Patrascu, Michael, Spatari, Sabrina

“…Mechanochemical methods are currently under investigation as alternative approaches to conventional solvent-batch synthetic chemistry. Environmental life cycle…”
Get full text