Search Results - "McCallum, Lynn"

The Impact of LED Lighting Spectra in a Plant Factory on the Growth, Physiological Traits and Essential Oil Content of Lemon Balm ( Melissa officinalis ) by Rihan, Hail Z, Aljafer, Naofel, Jbara, Marwa, McCallum, Lynn, Lengger, Sabine, Fuller, Michael P

“…With the recent development of LED lighting systems for plant cultivation, the use of vertical farming under controlled conditions is attracting increased…”
Get full text

The anti-migratory effects of FKBPL and its peptide derivative, AD-01: regulation of CD44 and the cytoskeletal pathway by Yakkundi, Anita, McCallum, Lynn, O'Kane, Anthony, Dyer, Hayder, Worthington, Jenny, McKeen, Hayley D, McClements, Lana, Elliott, Christopher, McCarthy, Helen O, Hirst, David G, Robson, Tracy

“…FK506 binding protein-like (FKBPL) and its peptide derivatives exert potent anti-angiogenic activity in vitro and in vivo and control tumour growth in…”
Get full text

MicroRNAs 130a/b are regulated by BCR-ABL and downregulate expression of CCN3 in CML by Suresh, Sukanya, McCallum, Lynn, Lu, Wanhua, Lazar, Noureddine, Perbal, Bernard, Irvine, Alexandra E.

“…Chronic Myeloid Leukaemia (CML) is a myeloproliferative disorder characterized by the expression of the oncoprotein, Bcr-Abl kinase. CCN3 normally functions as…”
Get full text

A novel mechanism for BCR-ABL action: stimulated secretion of CCN3 is involved in growth and differentiation regulation by McCallum, Lynn, Price, Susan, Planque, Nathalie, Perbal, Bernard, Pierce, Andrew, Whetton, Anthony D., Irvine, Alexandra E.

“…Chronic myeloid leukemia (CML) is characterized by the presence of the constitutively active BCR-ABL protein tyrosine kinase. Using a multipotent hemopoietic…”
Get full text

D-limonene suppresses RANKL-induced osteoclast differentiation and promotes osteoblast activity in-vitro by McCallum, Lynn, Fox, Simon W

“…Abstract Treatments for osteoporosis are typically given post-fracture. Therefore, identifying safe prophylactic interventions to reduce fracture risk would be…”
Get full text

Proteasome proteolytic profile is linked to Bcr-Abl expression by Crawford, Lisa J, Windrum, Phlip, Magill, Laura, Melo, Junia V, McCallum, Lynn, McMullin, Mary F, Ovaa, Huib, Walker, Brian, Irvine, Alexandra E

“…Objective We have previously demonstrated that proteasome activity is higher in bone marrow from patients with chronic myeloid leukemia (CML) than normal…”
Get full text

Influence of Intracerebral Hemorrhage Location on Incidence, Characteristics, and Outcome: Population-Based Study by Samarasekera, Neshika, Lerpiniere, Christine, Farrall, Andrew J, White, Philip M, Al-Shahi Salman, Rustam, Ahmad, Kate, Andrews, Peter, Bodkin, Peter, Campbell, Brian, Chandran, Siddharthan, Davenport, Richard, Dennis, Martin, Derry, Chris, Dodds, Katrina, Doubal, Fergus, Elder, Andrew, Fitzpatrick, Mike, Fouyas, Ioannis, Ghosh, Sudipto, Gordon, Claire, Hewett, Russell, Hughes, Fiona, Hunt, David, Hunter, Neil, Ironside, James, Liaquat, Imran, Kamat, Anant, Kealley, Susan, Kerr, Gillian, Kerrigan, Simon, Keston, Peter, Macdonald, Elizabeth, Macleod, Donald, Maxwell, Fiona, Millar, Tracey, Murray, Katherine, Myles, Lynn, Nimmo, Graham, Ng, Yi, Pal, Suvankar, Rannikmae, Kristiina, Ross, Jerard, Russell, Tim, Sandercock, Peter, Shanmuganathan, Mano, Shekhar, Himanshu, Simms, Henry, Soleiman, Hamza, Spiers, Helen, Stavrinos, Neo, Stone, Jon, Stuart, Joyce, Sudlow, Cathie, Summers, David, Taylor, Pat, Torgersen, Antonia, Walker, Robert, Weller, Belinda, Will, Robert, Anderson, Judith, Broadbent, Seona, Butler, Laura, Caesar, Dave, Cantley, Patricia, Clegg, Gareth, Crosswaite, Alastair, Duncan, Fiona, Elder-Gracie, Trish, Enright, Kate, Fothergill, Jane, Frier, Brian, Gray, Alasdair, Henderson, Robin, Jaap, Alan, Leigh-Smith, Simon, Jones, Michael, McCallum, Lynn, McKechnie, Martin, Morley, Wendy, Morrow, Frank, Ogundipe, Olayinka, Patel, Dilip, Pollock, Alison, Roberts, Geraint, Selvarajah, Johann, Smith, Randy, Stirling, Claire, Yordanov, Stanko, Chambers, Sarah, Jacob, Ashok, Jackson, Katherine, Knox, Anne, McCafferty, Jon, Noble, Donald, Ramsay, Scott, Spence, Linda, Threlfall, Bethany, Williams, Adrian, Jamieson, Andrew, Lange, Peter

“…BACKGROUND AND PURPOSE—The characteristics of intracerebral hemorrhage (ICH) may vary by ICH location because of differences in the distribution of underlying…”
Get full text

Molecular signatures for CCN1, p21 and p27 in progressive mantle cell lymphoma by Zaidi, Afak Rasheed Salman, Dresman, Sadie, Burt, Charlotte, Rule, Simon, McCallum, Lynn

“…Mantle cell lymphoma (MCL) is a comparatively rare non-Hodgkin’s lymphoma characterised by overexpression of cyclin D1. Many patients present with or progress…”
Get full text

The matricellular protein CCN3 regulates NOTCH1 signalling in chronic myeloid leukaemia by Suresh, Sukanya, McCallum, Lynn, Crawford, Lisa J, Lu, Wan Hua, Sharpe, Daniel J, Irvine, Alexandra E

“…Deregulated NOTCH1 has been reported in lymphoid leukaemia, although its role in chronic myeloid leukaemia (CML) is not well established. We previously…”
Get full text

Association of baseline hematoma and edema volumes with one-year outcome and long-term survival after spontaneous intracerebral hemorrhage: A community-based inception cohort study by Gane, Angus B, Middleton, Laura, Moullaali, Tom James, Rodrigues, Mark A, Cunningham, Laura, Wardlaw, Joanna, Al-Shahi Salman, Rustam, Samarasekera, Neshika, Addison, Anne, Ahmad, Kate, Chandran, Siddharthan, Cook, Helen, Davenport, Richard, Derry, Chris, Dodds, Katrina, Duncan, Susan, Elder, Andrew, Fouyas, Ioannis, Gibson, Rod, Hewett, Russell, Hughes, Fiona, Hughes, Mark, Hunter, Neil, Ironside, James, Liaquat, Imran, Josephson, Colin, Kamat, Anant, Kealley, Susan, Kerr, Gillian, Keston, Peter, King, Matthew, Macdonald, Elizabeth, Mackay, Graham, Macleod, Donald, Maguire, Conor, Makin, Steven, Mathews, Ashok, Maxwell, Fiona, McClellan, Stuart, Morris, Zoe, Morse, Tim, Mumford, Colin, Myles, Lynn, Nimmo, Graham, Rannikmae, Kristiina, Rhodes, Jonathan, Shanmuganathan, Mano, Shekhar, Himanshu, Simms, Henry, Smith, Colin, Stone, Jon, Stuart, Joyce, Sudlow, Cathie, Summers, David, Taylor, Pat, Torgersen, Antonia, van Dijke, Margarethe, Walker, Robert, Weller, Belinda, Whiteley, William, Young, Wendy, Broadbent, Seona, Butler, Laura, Cantley, Patricia, Carter, Jonathan, Clegg, Gareth, Coull, Andrew, Crosswaite, Alastair, Dummer, Simon, Duncan, Fiona, Enright, Kate, Frier, Brian, Grant, David, Gray, Alasdair, Hart, Simon, Henderson, Robin, Jones, Michael, Masson, Moyra, McCallum, Lynn, Mead, Gillian, Morley, Wendy, Morrow, Billie, Morrow, Frank, Murphy, Ross, Ogundipe, Olayinka, Patel, Dilip, Reed, Matthew, Roberts, Geraint, Yordanov, Stanko, Bell, Nicola, Farquhar, Donald, Jackson, Katherine, Knox, Anne, McCafferty, Jon, Munang, Latana, Spence, Linda, Williams, Andrew, Fitzgerald, Alastair, Lange, Peter, McIntosh, Andrew

“…Background Hospital-based studies have reported variable associations between outcome after spontaneous intracerebral hemorrhage and peri-hematomal edema…”
Get full text

The matricellular protein CCN3 regulates NOTCH1 signalling in chronic myeloid leukaemia: NOTCH1-CCN3 signalling in CML by Suresh, Sukanya, McCallum, Lynn, Crawford, Lisa J, Lu, Wan Hua, Sharpe, Daniel J, Irvine, Alexandra E

Get full text

FKBPL and Peptide Derivatives: Novel Biological Agents that Inhibit Angiogenesis by a CD44-Dependent Mechanism by VALENTINE, Andrea, O'ROURKE, Martin, MCKEEN, Hayley, WAUGH, David J. J, ROBERTS, Jennifer, MCGREGOR, Joanne, COTTON, Graham, JAMES, Lain, HARRISON, Timothy, HIRST, David G, ROBSON, Tracy, YAKKUNDI, Anita, WORTHINGTON, Jenny, HOOKHAM, Michelle, BICKNELL, Roy, MCCARTHY, Helen O, MCCLELLAND, Keeva, MCCALLUM, Lynn, DYER, Hayder

“…Antiangiogenic therapies can be an important adjunct to the management of many malignancies. Here we investigated a novel protein, FKBPL, and peptide…”
Get full text

CCN3 suppresses mitogenic signalling and reinstates growth control mechanisms in Chronic Myeloid Leukaemia by McCallum, Lynn, Lu, Wanhua, Price, Susan, Lazar, Noureddine, Perbal, Bernard, Irvine, Alexandra E.

“…CCN3, a tumour suppressor gene, is down-regulated as a result of BCR-ABL tyrosine kinase activity in Chronic Myeloid Leukaemia (CML). We have established a…”
Get full text

CCN3, a Novel Growth Inhibitory Factor for Chronic Myeloid Leukemia by Lu, Wanhua, McCallum, Lynn, Perbal, Bernard, Lazar, Nourreddine, Irvine, Alexandra

“…Chronic Myeloid Leukaemia (CML) is characterized by expression of the constitutively active BCR-ABL tyrosine kinase. Previously, we identified down-regulation…”
Get full text

National ambulatory emergency care survey: Current level of adoption and considerations for the future by McCallum, Lynn, Bell, Derek, Sturgess, Ian, Lawrence, Kate

“…Ambulatory emergency care (AEC), ie managing emergency patients without an overnight hospital stay, offers an alternative to routine hospital admission and…”
Get full text

0169 Simulation in acute medicine: A novel multi-disciplinary team training programme mapped to the UK core medical training curriculum by Thethy, Ishwinder, Butler, Laura, Ramsay, Hannah, Talbot, Harriet, Dover, Anna, McCallum, Lynn

“…BackgroundSimulation-based medical education (SBME) is increasingly used in healthcare to improve training, quality of care and patient safety.1 It facilitates…”
Get full text

CCN3: a key growth regulator in Chronic Myeloid Leukaemia by McCallum, Lynn, Lu, Wanhua, Price, Susan, Lazar, Noureddine, Perbal, Bernard, Irvine, Alexandra E.

“…Chronic Myeloid Leukaemia (CML) is characterized by expression of the constitutively active Bcr-Abl tyrosine kinase. We have shown previously that the negative…”
Get full text

A rapid and sensitive method for measuring cell adhesion by Lu, Wanhua, McCallum, Lynn, Irvine, Alexandra E.

“…We have adapted the CyQuant® assay to provide a simple, rapid, sensitive and highly reproducible method for measuring cell adhesion. The modified CyQuant®…”
Get full text

Bcr-Abl Positive Cells Display Increased Proteasome Activity and Greater Sensitivity to Proteasome Inhibition by Crawford, Lisa, Windrum, Philip, Magill, Laura, Melo, Junia V., McCallum, Lynn, McMullin, MaryFrances, Ovaa, Huib, Walker, Brian, Irvine, Alexandra

“…Chronic myeloid leukemia (CML) is a malignant disorder of the hematopoietic stem cell, characterised by the constitutively active tyrosine kinase BCR-ABL. The…”
Get full text

BCR-ABL Decreases the Expression of CCN3 Leading to Increased Clonogenic Potential and Cell Growth by McCallum, Lynn M.R., Lu, Wanhua, Price, Susan, Planque, Nathalie, Perbal, Bernard, Pierce, Andrew, Whetton, Anthony, Irvine, Alexandra E.

“…Chronic Myeloid Leukemia (CML) is characterized by expression of the constitutively active BCR-ABL tyrosine kinase. Previously, we have identified…”
Get full text