Search Results - "McCall, Patrick"
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1
Chemical Kinetics and Mass Action in Coexisting Phases
Published in Journal of the American Chemical Society (26-10-2022)“…The kinetics of chemical reactions are determined by the law of mass action, which has been successfully applied to homogeneous, dilute mixtures. At nondilute…”
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2
Partitioning and Enhanced Self-Assembly of Actin in Polypeptide Coacervates
Published in Biophysical journal (10-04-2018)“…Biomolecules exist and function in cellular microenvironments that control their spatial organization, local concentration, and biochemical reactivity. Due to…”
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3
Cofilin drives rapid turnover and fluidization of entangled F-actin
Published in Proceedings of the National Academy of Sciences - PNAS (25-06-2019)“…The shape of most animal cells is controlled by the actin cortex, a thin network of dynamic actin filaments (F-actin) situated just beneath the plasma…”
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4
Partitioning of cancer therapeutics in nuclear condensates
Published in Science (American Association for the Advancement of Science) (19-06-2020)“…The nucleus contains diverse phase-separated condensates that compartmentalize and concentrate biomolecules with distinct physicochemical properties. Here, we…”
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5
Filament turnover tunes both force generation and dissipation to control long-range flows in a model actomyosin cortex
Published in PLoS computational biology (01-12-2017)“…Actomyosin-based cortical flow is a fundamental engine for cellular morphogenesis. Cortical flows are generated by cross-linked networks of actin filaments and…”
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6
Antigenic cartography of H1N1 influenza viruses using sequence-based antigenic distance calculation
Published in BMC bioinformatics (12-02-2018)“…The ease at which influenza virus sequence data can be used to estimate antigenic relationships between strains and the existence of databases containing…”
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7
Self-Organization of Myosin II in Reconstituted Actomyosin Bundles
Published in Biophysical journal (19-09-2012)“…Cells assemble a variety of bundled actomyosin structures in the cytoskeleton for activities such as cell-shape regulation, force production, and cytokinesis…”
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8
Macromolecular condensation buffers intracellular water potential
Published in Nature (London) (23-11-2023)“…Optimum protein function and biochemical activity critically depends on water availability because solvent thermodynamics drive protein folding and…”
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Reconstitution of the transition from a lamellipodia- to filopodia-like actin network with purified proteins
Published in European journal of cell biology (01-12-2023)“…How cells utilize complex mixtures of actin binding proteins to assemble and maintain functionally diverse actin filament networks with distinct architectures…”
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10
Characterization of Photoactivated Singlet Oxygen Damage in Single-Molecule Optical Trap Experiments
Published in Biophysical journal (21-10-2009)“…Optical traps or “tweezers” use high-power, near-infrared laser beams to manipulate and apply forces to biological systems, ranging from individual molecules…”
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11
Stress relaxation in F-actin solutions by severing
Published in Soft matter (21-08-2019)“…Networks of filamentous actin (F-actin) are important for the mechanics of most animal cells. These cytoskeletal networks are highly dynamic, with a variety of…”
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Author Correction: Macromolecular condensation buffers intracellular water potential
Published in Nature (London) (25-04-2024)Get full text
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13
When Is "Enough" Enough?
Published in Cell systems (24-05-2017)“…Computational simulations of polymerizing actin filaments indicate that competition for a limiting pool of building blocks is not sufficient to control their…”
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14
Abstract GS3-10: Partitioning of cancer therapeutics in nuclear condensates
Published in Cancer research (Chicago, Ill.) (15-02-2021)“…The molecules of the cell are compartmentalized into membrane- and non-membrane-bound organelles. Many non-membrane-bound organelles are phase-separated…”
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15
College as country club: Do colleges cater to students' preferences for consumption?
Published in Journal of labor economics (01-04-2018)“…This paper investigates whether demand-side market pressure explains colleges’ decisions to provide consumption amenities to their students. Using a discrete…”
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Consequences of Molecular-Scale Non-Equilibrium Activity on the Dynamics and Mechanics of Self-Assembled Actin-Based Structures and Materials
Published 2017“…Living cells are hierarchically self-organized forms of active soft matter: molecules on the nanometer scale form functional structures and organelles on the…”
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Dissertation -
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Self-Organization in Reconstituted Actomyosin Bundles
Published in Biophysical journal (01-02-2011)Get full text
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18
The Phenotypic Effects of Expressing Mutant VHL in a VHL-Knockdown PC12 Line
Published 01-01-2012“…von Hippel-Lindau (VHL) disease is a family cancer syndrome resulting from inactivation of the VHL gene. Patients with VHL disease typically inherit one mutant…”
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Dissertation -
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Chemical Kinetics and Mass Action in Coexisting Phases
Published 14-12-2021“…The kinetics of chemical reactions are determined by the law of mass action, which has been successfully applied to homogeneous, dilute mixtures. At non-dilute…”
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Journal Article -
20
Identity and in-group/out-group differentiation in work and giving behaviors: Experimental evidence
Published in Journal of economic behavior & organization (01-10-2009)“…We investigate the existence and relative strength of favoritism for in-group versus out-group along multiple identity categories (body type, political views,…”
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