Search Results - "McCall, G"
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Distinct Subpopulations of Nucleus Accumbens Dynorphin Neurons Drive Aversion and Reward
Published in Neuron (Cambridge, Mass.) (02-09-2015)“…The nucleus accumbens (NAc) and the dynorphinergic system are widely implicated in motivated behaviors. Prior studies have shown that activation of…”
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Redefining Noradrenergic Neuromodulation of Behavior: Impacts of a Modular Locus Coeruleus Architecture
Published in The Journal of neuroscience (16-10-2019)“…The locus coeruleus (LC) is a seemingly singular and compact neuromodulatory nucleus that is a prominent component of disparate theories of brain function due…”
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3
CRH Engagement of the Locus Coeruleus Noradrenergic System Mediates Stress-Induced Anxiety
Published in Neuron (Cambridge, Mass.) (05-08-2015)“…The locus coeruleus noradrenergic (LC-NE) system is one of the first systems engaged following a stressful event. While numerous groups have demonstrated that…”
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4
Locus coeruleus to basolateral amygdala noradrenergic projections promote anxiety-like behavior
Published in eLife (14-07-2017)“…Increased tonic activity of locus coeruleus noradrenergic (LC-NE) neurons induces anxiety-like and aversive behavior. While some information is known about the…”
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5
Wireless Optofluidic Systems for Programmable In Vivo Pharmacology and Optogenetics
Published in Cell (30-07-2015)“…In vivo pharmacology and optogenetics hold tremendous promise for dissection of neural circuits, cellular signaling, and manipulating neurophysiological…”
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6
Pain-Induced Negative Affect Is Mediated via Recruitment of The Nucleus Accumbens Kappa Opioid System
Published in Neuron (Cambridge, Mass.) (08-05-2019)“…Negative affective states affect quality of life for patients suffering from pain. These maladaptive emotional states can lead to involuntary opioid overdose…”
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7
Spatiotemporal Control of Opioid Signaling and Behavior
Published in Neuron (Cambridge, Mass.) (20-05-2015)“…Optogenetics is now a widely accepted tool for spatiotemporal manipulation of neuronal activity. However, a majority of optogenetic approaches use binary…”
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8
Dynorphin Controls the Gain of an Amygdalar Anxiety Circuit
Published in Cell reports (Cambridge) (29-03-2016)“…Kappa opioid receptors (KORs) are involved in a variety of aversive behavioral states, including anxiety. To date, a circuit-based mechanism for KOR-driven…”
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9
Fabrication and application of flexible, multimodal light-emitting devices for wireless optogenetics
Published in Nature protocols (01-12-2013)“…The rise of optogenetics provides unique opportunities to advance materials and biomedical engineering, as well as fundamental understanding in neuroscience…”
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10
Stretchable multichannel antennas in soft wireless optoelectronic implants for optogenetics
Published in Proceedings of the National Academy of Sciences - PNAS (13-12-2016)“…Optogenetic methods to modulate cells and signaling pathways via targeted expression and activation of light-sensitive proteins have greatly accelerated the…”
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11
Nicotine aversion is mediated by GABAergic interpeduncular nucleus inputs to laterodorsal tegmentum
Published in Nature communications (13-07-2018)“…Nicotine use can lead to dependence through complex processes that are regulated by both its rewarding and aversive effects. Recent studies show that aversive…”
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12
Low Fuel Convergence Path to Direct-Drive Fusion Ignition
Published in Physical review letters (24-06-2016)“…A new class of inertial fusion capsules is presented that combines multishell targets with laser direct drive at low intensity (2.8×10^{14} W/cm^{2}) to…”
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The Vendian (Ediacaran) in the geological record: Enigmas in geology's prelude to the Cambrian explosion
Published in Earth-science reviews (01-07-2006)“…Up to the 1950s, the Precambrian was regarded as unrewardingly unfossiliferous, records of fossils being isolated, few in number and dubious. The change came…”
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14
Mechanically transformative electronics, sensors, and implantable devices
Published in Science advances (01-11-2019)“…A platform built with novel materials and manufacturing strategies enables electronics adaptable for various applications. Traditionally, electronics have been…”
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15
Surgical extraction of human dorsal root ganglia from organ donors and preparation of primary sensory neuron cultures
Published in Nature protocols (01-10-2016)“…This is a protocol for preparing human dorsal root ganglia and establishing primary sensory neuron cultures for functional analysis by electrophysiological…”
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16
Photo-activatable Cre recombinase regulates gene expression in vivo
Published in Scientific reports (09-09-2015)“…Techniques allowing precise spatial and temporal control of gene expression in the brain are needed. Herein we describe optogenetic approaches using a…”
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17
In vivo detection of optically-evoked opioid peptide release
Published in eLife (03-09-2018)“…Though the last decade has seen accelerated advances in techniques and technologies to perturb neuronal circuitry in the brain, we are still poorly equipped to…”
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18
An open-source device for measuring food intake and operant behavior in rodent home-cages
Published in eLife (29-03-2021)“…Feeding is critical for survival, and disruption in the mechanisms that govern food intake underlies disorders such as obesity and anorexia nervosa. It is…”
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Implantable Optofluidic Systems for Wireless In Vivo Photopharmacology
Published in ChemPhotoChem (01-02-2021)“…Photopharmacology, which uses chemical photoswitches for the optical manipulation of biological process, holds immense potential for neuroscience and clinical…”
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20
The carbonado diamond conundrum
Published in Earth-science reviews (01-04-2009)“…The reviewer presents the results of a literature search on the enigmatic occurrences of carbonado; a form (but not the only form) of polycrystalline diamond,…”
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