Search Results - "McBride, H."
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Radiation‐induced tissue damage and response
Published in The Journal of pathology (01-04-2020)“…Normal tissue responses to ionizing radiation have been a major subject for study since the discovery of X‐rays at the end of the 19th century. Shortly…”
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2
Radiation Resistance of Cancer Stem Cells: The 4 R's of Radiobiology Revisited
Published in Stem cells (Dayton, Ohio) (01-04-2010)“…There is compelling evidence that many solid cancers are organized hierarchically and contain a small population of cancer stem cells (CSCs). It seems…”
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3
Maximizing Tumor Immunity With Fractionated Radiation
Published in International journal of radiation oncology, biology, physics (15-07-2012)“…Purpose Technologic advances have led to increased clinical use of higher-sized fractions of radiation dose and higher total doses. How these modify the…”
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4
Radiation and Inflammation
Published in Seminars in radiation oncology (2015)“…The immune system has the power to modulate the expression of radiation-induced normal and tumor tissue damage. On the one hand, it can contribute to cancer…”
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5
Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics
Published in Human molecular genetics (01-10-2010)“…Growing evidence highlights a role for mitochondrial dysfunction and oxidative stress as underlying contributors to Parkinson's disease (PD) pathogenesis. DJ-1…”
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Bioactive impact of manuka honey and bone char incorporated into gelatin and chitosan cryogels in a rat calvarial fracture model
Published in Journal of biomedical materials research. Part B, Applied biomaterials (01-10-2023)“…Bone tissue engineered scaffolds are designed to mimic the natural environment for regeneration when typical healing is inhibited. Autografts are the current…”
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7
Radiation Enhances Regulatory T Cell Representation
Published in International journal of radiation oncology, biology, physics (15-11-2011)“…Purpose Immunotherapy could be a useful adjunct to standard cytotoxic therapies such as radiation in patients with micrometastatic disease, although successful…”
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8
After the bomb drops: A new look at radiation-induced multiple organ dysfunction syndrome (MODS)
Published in International journal of radiation biology (01-08-2011)“…Purpose: There is increasing concern that, since the Cold War era, there has been little progress regarding the availability of medical countermeasures in the…”
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9
Combining radiotherapy and immunotherapy: a revived partnership
Published in International journal of radiation oncology, biology, physics (01-11-2005)“…Ionizing radiation therapy (RT) is an important local modality for the treatment of cancer. The current rationale for its use is based largely on the ability…”
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10
Defined Sensing Mechanisms and Signaling Pathways Contribute to the Global Inflammatory Gene Expression Output Elicited by Ionizing Radiation
Published in Immunity (Cambridge, Mass.) (19-09-2017)“…Environmental insults are often detected by multiple sensors that activate diverse signaling pathways and transcriptional regulators, leading to a tailored…”
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Effects of radiation on normal tissue: consequences and mechanisms
Published in The lancet oncology (01-09-2003)“…The use of radiation therapy to treat cancer inevitably involves exposure of normal tissues. As a result, patients may experience symptoms associated with…”
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The epidemiology and clinical features of rickettsial diseases in North Queensland, Australia: Implications for patient identification and management
Published in PLoS neglected tropical diseases (01-07-2019)“…Rickettsial infections are a common cause of hospitalization in tropical settings, although early diagnosis is challenging in the rural locations where these…”
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13
Ionizing Radiation Activates the Nrf2 Antioxidant Response
Published in Cancer research (Chicago, Ill.) (01-11-2010)“…The transcription factor NF-E2-related factor 2 (Nrf2) binds the antioxidant DNA response element (ARE) to activate important cellular cytoprotective defense…”
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14
Capsaicin, a component of red peppers, inhibits the growth of androgen-independent, p53 mutant prostate cancer cells
Published in Cancer research (Chicago, Ill.) (15-03-2006)“…Capsaicin is the major pungent ingredient in red peppers. Here, we report that it has a profound antiproliferative effect on prostate cancer cells, inducing…”
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15
Clinical Manifestations of Cryptococcus gattii Infection: Determinants of Neurological Sequelae and Death
Published in Clinical infectious diseases (15-09-2012)“…Background. Longer-term morbidity and outcomes of Cryptococcus gattii infection are not described. We analyzed clinical, microbiological, and outcome data in…”
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16
Identification of miRNA signatures associated with radiation-induced late lung injury in mice
Published in PloS one (11-05-2020)“…Acute radiation exposure of the thorax can lead to late serious, and even life-threatening, pulmonary and cardiac damage. Sporadic in nature, late…”
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A preliminary in vitro evaluation of the bioactive potential of cryogel scaffolds incorporated with Manuka honey for the treatment of chronic bone infections
Published in Journal of biomedical materials research. Part B, Applied biomaterials (01-07-2018)“…Previous studies have identified honey as an agent in bacterial inhibition and a mediator in lowering the pH at the wound site. Manuka honey (MH), indigenous…”
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Uterine leiomyosarcomas are characterized by high p16, p53 and MIB1 expression in comparison with usual leiomyomas, leiomyoma variants and smooth muscle tumours of uncertain malignant potential
Published in Histopathology (01-06-2007)“…Aims: It has been suggested that p16 is overexpressed in uterine leiomyosarcomas in comparison with leiomyomas. In this study, p16 immunohistochemical…”
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Biomimetic sponges for regeneration of skeletal muscle following trauma
Published in Journal of biomedical materials research. Part A (01-01-2019)“…Skeletal muscle is inept in regenerating after traumatic injuries due to significant loss of basal lamina and the resident satellite cells. To improve…”
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Antifungal Therapy and Management of Complications of Cryptococcosis due to Cryptococcus gattii
Published in Clinical infectious diseases (15-08-2013)“…Background. We describe antifungal therapy and management of complications due to Cryptococcus gattii infection in 86 Australian patients followed for at least…”
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