Search Results - "McBride, Christie M."

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  1. 1
    Trafficking-deficient hERG K⁺ channels linked to long QT syndrome are regulated by a microtubule-dependent quality control compartment in the ER

    Trafficking-deficient hERG K⁺ channels linked to long QT syndrome are regulated by a microtubule-dependent quality control compartment in the ER by Smith, Jennifer L, McBride, Christie M, Nataraj, Parvathi S, Bartos, Daniel C, January, Craig T, Delisle, Brian P

    “…The human ether-a-go-go related gene (hERG) encodes the voltage-gated K(+) channel that underlies the rapidly activating delayed-rectifier current in cardiac…”
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  2. 2
    Mechanistic Basis for Type 2 Long QT Syndrome Caused by KCNH2 Mutations that Disrupt Conserved Arginine Residues in the Voltage Sensor

    Mechanistic Basis for Type 2 Long QT Syndrome Caused by KCNH2 Mutations that Disrupt Conserved Arginine Residues in the Voltage Sensor by McBride, Christie M., Smith, Ashley M., Smith, Jennifer L., Reloj, Allison R., Velasco, Ellyn J., Powell, Jonathan, Elayi, Claude S., Bartos, Daniel C., Burgess, Don E., Delisle, Brian P.

    Published in The Journal of membrane biology (01-05-2013)
    “…KCNH2 encodes the Kv11.1 channel, which conducts the rapidly activating delayed rectifier K + current ( I Kr ) in the heart. KCNH2 mutations cause type 2 long…”
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  3. 3
    Long QT-Linked HERG Mutations at R531 of the S4 Alter the Gating Properties of Wt-HERG

    Long QT-Linked HERG Mutations at R531 of the S4 Alter the Gating Properties of Wt-HERG by McBride, Christie M., Powell, Jonathan, Smith, Ashley, Delisle, Brian P.

    Published in Biophysical journal (01-02-2011)
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  4. 4
    Pharmacological-Induced Increase in the Functional Expression Of hERG Current

    Pharmacological-Induced Increase in the Functional Expression Of hERG Current by McBride, Christie M., Smith, Jennifer L., Delisle, Brian P.

    Published in Biophysical journal (01-01-2010)
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  5. 5
    Microtubule Dependent Mechanisms Regulate the Trafficking Deficient Phenotype of hERG Mutations Linked to Long QT Syndrome

    Microtubule Dependent Mechanisms Regulate the Trafficking Deficient Phenotype of hERG Mutations Linked to Long QT Syndrome by Smith, Jennifer L., McBride, Christie M., Bartos, Daniel C., January, Craig T., Delisle, Brian

    Published in Biophysical journal (01-01-2010)
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  6. 6
    Mechanistic Basis for Type 2 Long QT Syndrome Caused by KCNH2 Mutations that Disrupt Conserved Arginine Residue in the Voltage Sensor

    Mechanistic Basis for Type 2 Long QT Syndrome Caused by KCNH2 Mutations that Disrupt Conserved Arginine Residue in the Voltage Sensor by McBride, Christie M., Smith, Ashley M., Smith, Jennifer L., Reloj, Allison R., Velasco, Ellyn J., Powell, Jonathan, Elayi, Claude S., Bartos, Daniel C., Burgess, Don E., Delisle, Brian P.

    Published in The Journal of membrane biology (02-04-2013)
    “…KCNH2 encodes the Kv11.1 channel, which conducts the rapidly activating delayed rectifier K + current ( I Kr ) in the heart. KCNH2 mutations cause type 2 long…”
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