Search Results - "McBee, Megan E"

Quantitative analysis of ribonucleoside modifications in tRNA by HPLC-coupled mass spectrometry by Su, Dan, Chan, Clement T Y, Gu, Chen, Lim, Kok Seong, Chionh, Yok Hian, McBee, Megan E, Russell, Brandon S, Babu, I Ramesh, Begley, Thomas J, Dedon, Peter C

“…Post-transcriptional modification of RNA is an important determinant of RNA quality control, translational efficiency, RNA-protein interactions and stress…”
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Utility of the Citrobacter rodentium infection model in laboratory mice by Borenshtein, Diana, McBee, Megan E, Schauer, David B

“…PURPOSE OF REVIEWThere have been considerable advances in our understanding of the molecular pathogenesis of enteropathogenic Escherichia coli and…”
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Crystal structure and catalytic mechanism of the essential m1G37 tRNA methyltransferase TrmD from Pseudomonas aeruginosa by Jaroensuk, Juthamas, Wong, Yee Hwa, Zhong, Wenhe, Liew, Chong Wai, Maenpuen, Somchart, Sahili, Abbas E, Atichartpongkul, Sopapan, Chionh, Yok Hian, Nah, Qianhui, Thongdee, Narumon, McBee, Megan E, Prestwich, Erin G, DeMott, Michael S, Chaiyen, Pimchai, Mongkolsuk, Skorn, Dedon, Peter C, Lescar, Julien, Fuangthong, Mayuree

“…The tRNA (m1G37) methyltransferase TrmD catalyzes m1G formation at position 37 in many tRNA isoacceptors and is essential in most bacteria, which positions it…”
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Facile metabolic reprogramming distinguishes mycobacterial adaptation to hypoxia and starvation: ketosis drives starvation-induced persistence in M. bovis BCG by Davis, Nick K., Chionh, Yok Hian, McBee, Megan E., Hia, Fabian, Ma, Duanduan, Cui, Liang, Sharaf, Mariam Lucila, Cai, Weiling Maggie, Jumpathong, Watthanachai, Levine, Stuart S., Alonso, Sylvie, Dedon, Peter C.

“…Mycobacteria adapt to infection stresses by entering a reversible non-replicating persistence (NRP) with slow or no cell growth and broad antimicrobial…”
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A rapid simple point-of-care assay for the detection of SARS-CoV-2 neutralizing antibodies by Kongsuphol, Patthara, Jia, Huan, Cheng, Hoi Lok, Gu, Yue, Shunmuganathan, Bhuvaneshwari D/O, Chen, Ming Wei, Lim, Sing Mei, Ng, Say Yong, Tambyah, Paul Ananth, Nasir, Haziq, Gao, Xiaohong, Tay, Dousabel, Kim, Seunghyeon, Gupta, Rashi, Qian, Xinlei, Kozma, Mary M., Purushotorman, Kiren, McBee, Megan E., MacAry, Paul A., Sikes, Hadley D., Preiser, Peter R.

“…Background Neutralizing antibodies (NAbs) prevent pathogens from infecting host cells. Detection of SARS-CoV-2 NAbs is critical to evaluate herd immunity and…”
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EHEC Type III Effector NleL Is an E3 Ubiquitin Ligase That Modulates Pedestal Formation by Piscatelli, Heather, Kotkar, Shalaka A, McBee, Megan E, Muthupalani, Sureshkumar, Schauer, David B, Mandrell, Robert E, Leong, John M, Zhou, Daoguo, van der Goot, F. Gisou

“…Enterohemorrhagic Escherichia coli (EHEC) O157:H7 causes hemorrhagic colitis and may result in potentially fatal hemolytic uremia syndrome in humans. EHEC…”
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Alkyl Hydroperoxide Reductase Is Required for Helicobacter cinaedi Intestinal Colonization and Survival under Oxidative Stress in BALB/c and BALB/c Interleukin-10−/− Mice by CHAROENLAP, Nisanart, ZELI SHEN, MCBEE, Megan E, MUTHUPALANI, Suresh, WOGAN, Gerald N, FOX, James G, SCHAUER, David B

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Rapid Evaluation of Vaccine Booster Effectiveness against SARS-CoV-2 Variants by Cheng, Hoi Lok, Lim, Sing Mei, Jia, Huan, Chen, Ming Wei, Ng, Say Yong, Gao, Xiaohong, Somani, Jyoti, Sengupta, Sharmila, Tay, Dousabel M Y, Chua, Patrina W L, R, Abirami, Ling, Sharon Y H, McBee, Megan E, Young, Barnaby E, Sikes, Hadley D, Preiser, Peter R

“…As the COVID-19 pandemic continues, countries around the world are switching toward vaccinations and boosters to combat the pandemic. However, waning immunity…”
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Finger stick blood test to assess postvaccination SARS‐CoV‐2 neutralizing antibody response against variants by Lim, Sing Mei, Cheng, Hoi Lok, Jia, Huan, Kongsuphol, Patthara, D/O Shunmuganathan, Bhuvaneshwari, Chen, Ming Wei, Ng, Say Yong, Gao, Xiaohong, Turaga, Shuvan Prashant, Heussler, Sascha P., Somani, Jyoti, Sengupta, Sharmila, Tay, Dousabel M. Y., McBee, Megan E., Young, Barnaby E., MacAry, Paul A., Sikes, Hadley D., Preiser, Peter R.

“…There is clinical need for a quantifiable point‐of‐care (PoC) SARS‐CoV‐2 neutralizing antibody (nAb) test that is adaptable with the pandemic's changing…”
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Toll-Like Receptor 4-Mediated Regulation of Spontaneous Helicobacter -Dependent Colitis in IL-10–Deficient Mice by Matharu, Kabir S, Mizoguchi, Emiko, Cotoner, Carmen Alonso, Nguyen, Deanna D, Mingle, Bethany, Iweala, Onyinye I, McBee, Megan E, Stefka, Andrew T, Prioult, Guenolee, Haigis, Kevin M, Bhan, Atul K, Snapper, Scott B, Murakami, Hidehiro, Schauer, David B, Reinecker, Hans–Christian, Mizoguchi, Atsushi, Nagler, Cathryn R

“…Background & Aims The commensal microbiota is believed to have an important role in regulating immune responsiveness and preventing intestinal inflammation…”
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Multivariate modeling identifies neutrophil- and Th17-related factors as differential serum biomarkers of chronic murine colitis by McBee, Megan E, Zeng, Yu, Parry, Nicola, Nagler, Cathryn R, Tannenbaum, Steven R, Schauer, David B

“…Diagnosis of chronic intestinal inflammation, which characterizes inflammatory bowel disease (IBD), along with prediction of disease state is hindered by the…”
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Production of Superoxide in Bacteria Is Stress- and Cell State-Dependent: A Gating-Optimized Flow Cytometry Method that Minimizes ROS Measurement Artifacts with Fluorescent Dyes by McBee, Megan E, Chionh, Yok H, Sharaf, Mariam L, Ho, Peiying, Cai, Maggie W L, Dedon, Peter C

“…The role of reactive oxygen species (ROS) in microbial metabolism and stress response has emerged as a major theme in microbiology and infectious disease…”
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Modulation of Acute Diarrheal Illness by Persistent Bacterial Infection by McBee, Megan E, Zheng, Patricia Z, Rogers, Arlin B, Fox, James G, Schauer, David B

“…Acute diarrheal illness is a global health problem that may be exacerbated by concurrent infection. Using Citrobacter rodentium, a murine model of attaching…”
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Electrostatic microfiltration (EM) enriches and recovers viable microorganisms at low-abundance in large-volume samples and enhances downstream detection by Liu, Yaoping, Raymond, Joshua J, Wu, Xiaolin, Chua, Patrina Wei Lin, Ling, Sharon Yan Han, Chan, Chia Ching, Chan, Cheryl, Loh, Joanne Xin Yi, Song, Melody Xing Yen, Ong, Matilda Yu Yan, Ho, Peiying, Mcbee, Megan E, Springs, Stacy L, Yu, Hanry, Han, Jongyoon

“…Rapid and sensitive detection of pathogens in various samples is crucial for disease diagnosis, environmental surveillance, as well as food and water safety…”
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Thienopyrimidinone Derivatives That Inhibit Bacterial tRNA (Guanine37‑N 1)‑Methyltransferase (TrmD) by Restructuring the Active Site with a Tyrosine-Flipping Mechanism by Zhong, Wenhe, Pasunooti, Kalyan Kumar, Balamkundu, Seetharamsing, Wong, Yee Hwa, Nah, Qianhui, Gadi, Vinod, Gnanakalai, Shanmugavel, Chionh, Yok Hian, McBee, Megan E, Gopal, Pooja, Lim, Siau Hoi, Olivier, Nelson, Buurman, Ed T, Dick, Thomas, Liu, Chuan Fa, Lescar, Julien, Dedon, Peter C

“…Among the >120 modified ribonucleosides in the prokaryotic epitranscriptome, many tRNA modifications are critical to bacterial survival, which makes their…”
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Development of a cellulose-based 96-well plate vertical flow pull-down assay by Cheng, Hoi Lok, Jia, Huan, Lim, Sing Mei, Ng, Say Yong, Kongsuphol, Patthara, McBee, Megan E, Sikes, Hadley D

“…The abundance and low production cost of biomaterial cellulose paper have attracted attention for many applications. Point-of-care (PoC) diagnostic tests have…”
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Methylation at position 32 of tRNA catalyzed by TrmJ alters oxidative stress response in Pseudomonas aeruginosa by Jaroensuk, Juthamas, Atichartpongkul, Sopapan, Chionh, Yok Hian, Wong, Yee Hwa, Liew, Chong Wai, McBee, Megan E, Thongdee, Narumon, Prestwich, Erin G, DeMott, Michael S, Mongkolsuk, Skorn, Dedon, Peter C, Lescar, Julien, Fuangthong, Mayuree

“…Bacteria respond to environmental stresses using a variety of signaling and gene expression pathways, with translational mechanisms being the least well…”
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A Platform for Discovery and Quantification of Modified Ribonucleosides in RNA: Application to Stress-Induced Reprogramming of tRNA Modifications by Cai, Weiling Maggie, Chionh, Yok Hian, Hia, Fabian, Gu, Chen, Kellner, Stefanie, McBee, Megan E, Ng, Chee Sheng, Pang, Yan Ling Joy, Prestwich, Erin G, Lim, Kok Seong, Babu, I Ramesh, Begley, Thomas J, Dedon, Peter C

“…Here we describe an analytical platform for systems-level quantitative analysis of modified ribonucleosides in any RNA species, with a focus on stress-induced…”
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A novel murine infection model for Shiga toxin-producing Escherichia coli by Mallick, Emily M, McBee, Megan E, Vanguri, Vijay K, Melton-Celsa, Angela R, Schlieper, Katherine, Karalius, Brad J, O'Brien, Alison D, Butterton, Joan R, Leong, John M, Schauer, David B

“…Enterohemorrhagic E. coli (EHEC) is an important subset of Shiga toxin-producing (Stx-producing) E. coli (STEC), pathogens that have been implicated in…”
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Crystal structure and catalytic mechanism of the essential m 1 G37 tRNA methyltransferase TrmD from Pseudomonas aeruginosa by Jaroensuk, Juthamas, Wong, Yee Hwa, Zhong, Wenhe, Liew, Chong Wai, Maenpuen, Somchart, Sahili, Abbas E, Atichartpongkul, Sopapan, Chionh, Yok Hian, Nah, Qianhui, Thongdee, Narumon, McBee, Megan E, Prestwich, Erin G, DeMott, Michael S, Chaiyen, Pimchai, Mongkolsuk, Skorn, Dedon, Peter C, Lescar, Julien, Fuangthong, Mayuree

“…The tRNA (m G37) methyltransferase TrmD catalyzes m G formation at position 37 in many tRNA isoacceptors and is essential in most bacteria, which positions it…”
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