Search Results - "McBain, Chris"

Neurogliaform cells in cortical circuits by Overstreet-Wadiche, Linda, McBain, Chris J.

“…Key Points Neurogliaform cells are a novel subtype of hippocampal and cortical local-circuit GABAergic inhibitory interneuron that primarily reside within the…”
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Hippocampal GABAergic Inhibitory Interneurons by Pelkey, Kenneth A, Chittajallu, Ramesh, Craig, Michael T, Tricoire, Ludovic, Wester, Jason C, McBain, Chris J

“…In the hippocampus GABAergic local circuit inhibitory interneurons represent only ~10-15% of the total neuronal population; however, their remarkable…”
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Young Dentate Granule Cells Mediate Pattern Separation, whereas Old Granule Cells Facilitate Pattern Completion by Nakashiba, Toshiaki, Cushman, Jesse D., Pelkey, Kenneth A., Renaudineau, Sophie, Buhl, Derek L., McHugh, Thomas J., Barrera, Vanessa Rodriguez, Chittajallu, Ramesh, Iwamoto, Keisuke S., McBain, Chris J., Fanselow, Michael S., Tonegawa, Susumu

“…Adult-born granule cells (GCs), a minor population of cells in the hippocampal dentate gyrus, are highly active during the first few weeks after functional…”
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Pentraxins Coordinate Excitatory Synapse Maturation and Circuit Integration of Parvalbumin Interneurons by Pelkey, Kenneth A., Barksdale, Elizabeth, Craig, Michael T., Yuan, Xiaoqing, Sukumaran, Madhav, Vargish, Geoffrey A., Mitchell, Robert M., Wyeth, Megan S., Petralia, Ronald S., Chittajallu, Ramesh, Karlsson, Rose-Marie, Cameron, Heather A., Murata, Yasunobu, Colonnese, Matthew T., Worley, Paul F., McBain, Chris J.

“…Circuit computation requires precision in the timing, extent, and synchrony of principal cell (PC) firing that is largely enforced by parvalbumin-expressing,…”
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Diverse roles for ionotropic glutamate receptors on inhibitory interneurons in developing and adult brain by Akgül, Gülcan, McBain, Chris J.

“…Glutamate receptor‐mediated recruitment of GABAergic inhibitory interneurons is a critical determinant of network processing. Early studies observed that many,…”
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Glutamate receptor ion channels: structure, regulation, and function by Traynelis, Stephen F, Wollmuth, Lonnie P, McBain, Chris J, Menniti, Frank S, Vance, Katie M, Ogden, Kevin K, Hansen, Kasper B, Yuan, Hongjie, Myers, Scott J, Dingledine, Ray

“…The mammalian ionotropic glutamate receptor family encodes 18 gene products that coassemble to form ligand-gated ion channels containing an agonist recognition…”
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Structure, Function, and Pharmacology of Glutamate Receptor Ion Channels by Hansen, Kasper B, Wollmuth, Lonnie P, Bowie, Derek, Furukawa, Hiro, Menniti, Frank S, Sobolevsky, Alexander I, Swanson, Geoffrey T, Swanger, Sharon A, Greger, Ingo H, Nakagawa, Terunaga, McBain, Chris J, Jayaraman, Vasanthi, Low, Chian-Ming, Dell'Acqua, Mark L, Diamond, Jeffrey S, Camp, Chad R, Perszyk, Riley E, Yuan, Hongjie, Traynelis, Stephen F

“…Many physiologic effects of l-glutamate, the major excitatory neurotransmitter in the mammalian central nervous system, are mediated via signaling by…”
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The Role of the GluR2 Subunit in AMPA Receptor Function and Synaptic Plasticity by Isaac, John T.R., Ashby, Michael C., McBain, Chris J.

“…The AMPA receptor (AMPAR) GluR2 subunit dictates the critical biophysical properties of the receptor, strongly influences receptor assembly and trafficking,…”
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Fast gamma oscillations are generated intrinsically in CA1 without the involvement of fast-spiking basket cells by Craig, Michael T, McBain, Chris J

“…Information processing in neuronal networks relies on the precise synchronization of ensembles of neurons, coordinated by the diverse family of inhibitory…”
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Timing isn't everything: opposing roles for perisomatic inhibition by Caccavano, Adam P, McBain, Chris J

“…Perisomatic inhibition from parvalbumin-containing (PV) interneurons is critical for timing, but the role of cholecystokinin-containing (CCK) interneurons…”
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Interneurons Differentially Contribute to Spontaneous Network Activity in the Developing Hippocampus Dependent on Their Embryonic Lineage by Wester, Jason C, McBain, Chris J

“…Spontaneously generated network activity is a hallmark of developing neural circuits, and plays an important role in the formation of synaptic connections. In…”
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NPTX2 and cognitive dysfunction in Alzheimer's Disease by Xiao, Mei-Fang, Xu, Desheng, Craig, Michael T, Pelkey, Kenneth A, Chien, Chun-Che, Shi, Yang, Zhang, Juhong, Resnick, Susan, Pletnikova, Olga, Salmon, David, Brewer, James, Edland, Steven, Wegiel, Jerzy, Tycko, Benjamin, Savonenko, Alena, Reeves, Roger H, Troncoso, Juan C, McBain, Chris J, Galasko, Douglas, Worley, Paul F

“…Memory loss in Alzheimer's disease (AD) is attributed to pervasive weakening and loss of synapses. Here, we present findings supporting a special role for…”
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Neocortical Projection Neurons Instruct Inhibitory Interneuron Circuit Development in a Lineage-Dependent Manner by Wester, Jason C., Mahadevan, Vivek, Rhodes, Christopher T., Calvigioni, Daniela, Venkatesh, Sanan, Maric, Dragan, Hunt, Steven, Yuan, Xiaoqing, Zhang, Yajun, Petros, Timothy J., McBain, Chris J.

“…Neocortical circuits consist of stereotypical motifs that must self-assemble during development. Recent evidence suggests that the subtype identity of both…”
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Vesicle Pools of Memory at Mossy Fiber Synapses by Vargish, Geoffrey A., McBain, Chris J.

“…In this issue of Neuron, Vandael et al. (2020) reveal that post-tetanic potentiation at dentate gyrus mossy fiber synapses is induced by natural activity…”
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New insights into the classification and nomenclature of cortical GABAergic interneurons by DeFelipe, Javier, López-Cruz, Pedro L., Benavides-Piccione, Ruth, Bielza, Concha, Larrañaga, Pedro, Anderson, Stewart, Burkhalter, Andreas, Cauli, Bruno, Fairén, Alfonso, Feldmeyer, Dirk, Fishell, Gord, Fitzpatrick, David, Freund, Tamás F., González-Burgos, Guillermo, Hestrin, Shaul, Hill, Sean, Hof, Patrick R., Huang, Josh, Jones, Edward G., Kawaguchi, Yasuo, Kisvárday, Zoltán, Kubota, Yoshiyuki, Lewis, David A., Marín, Oscar, Markram, Henry, McBain, Chris J., Meyer, Hanno S., Monyer, Hannah, Nelson, Sacha B., Rockland, Kathleen, Rossier, Jean, Rubenstein, John L. R., Rudy, Bernardo, Scanziani, Massimo, Shepherd, Gordon M., Sherwood, Chet C., Staiger, Jochen F., Tamás, Gábor, Thomson, Alex, Wang, Yun, Yuste, Rafael, Ascoli, Giorgio A.

“…Key Points A feature-based classification and agreed-upon nomenclature of GABAergic interneurons of the cerebral cortex is much needed but currently lacking…”
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Narp regulates homeostatic scaling of excitatory synapses on parvalbumin-expressing interneurons by Chang, Michael C, Park, Joo Min, Pelkey, Kenneth A, Grabenstatter, Heidi L, Xu, Desheng, Linden, David J, Sutula, Thomas P, McBain, Chris J, Worley, Paul F

“…The authors report that the immediate-early gene Narp accumulates at excitatory synapses on parvalbumin-expressing interneurons. Narp recruits AMPA receptors…”
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Behavioral state-dependent modulation of distinct interneuron subtypes and consequences for circuit function by Wester, Jason C, McBain, Chris J

“…Highlights • Interneuron subtypes are differentially modulated depending on behavioral context. • A distinct interneuron group expresses ionotropic serotonin…”
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AMPA receptor deletion in developing MGE-derived hippocampal interneurons causes a redistribution of excitatory synapses and attenuates postnatal network oscillatory activity by Akgül, Gülcan, McBain, Chris J.

“…Inhibitory interneurons derived from the medial ganglionic eminence represent the largest cohort of GABAergic neurons in the hippocampus. In the CA1…”
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GluN2D-Containing N-methyl-d-Aspartate Receptors Mediate Synaptic Transmission in Hippocampal Interneurons and Regulate Interneuron Activity by Perszyk, Riley E, DiRaddo, John O, Strong, Katie L, Low, Chian-Ming, Ogden, Kevin K, Khatri, Alpa, Vargish, Geoffrey A, Pelkey, Kenneth A, Tricoire, Ludovic, Liotta, Dennis C, Smith, Yoland, McBain, Chris J, Traynelis, Stephen F

“…N-methyl-d-aspartate receptors (NMDARs) are ionotropic glutamatergic receptors that have been implicated in learning, development, and neuropathological…”
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Molecular Dissection of Neuroligin 2 and Slitrk3 Reveals an Essential Framework for GABAergic Synapse Development by Li, Jun, Han, Wenyan, Pelkey, Kenneth A., Duan, Jingjing, Mao, Xia, Wang, Ya-Xian, Craig, Michael T., Dong, Lijin, Petralia, Ronald S., McBain, Chris J., Lu, Wei

“…In the brain, many types of interneurons make functionally diverse inhibitory synapses onto principal neurons. Although numerous molecules have been identified…”
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