Search Results - "McArthur, Monica A."

Zika Virus: Recent Advances towards the Development of Vaccines and Therapeutics by McArthur, Monica A

“…Zika is a rapidly emerging public health threat. Although clinical infection is frequently mild, significant neurological manifestations have been demonstrated…”
Get full text

Heterogeneity of multifunctional IL-17A producing S. Typhi-specific CD8+ T cells in volunteers following Ty21a typhoid immunization by McArthur, Monica A, Sztein, Marcelo B

“…Salmonella enterica serovar Typhi (S. Typhi), the causative agent of typhoid fever, continues to cause significant morbidity and mortality world-wide. CD8+ T…”
Get full text

Using Adjuvants to Drive T Cell Responses for Next-Generation Infectious Disease Vaccines by Rapaka, Rekha R., Cross, Alan S., McArthur, Monica A.

“…Using adjuvants to drive features of T cell responses to vaccine antigens is an important technological challenge in the design of new and improved vaccines…”
Get full text

Complex adaptive immunity to enteric fevers in humans: lessons learned and the path forward by Sztein, Marcelo B, Salerno-Goncalves, Rosangela, McArthur, Monica A

“…Salmonella enterica serovar Typhi (S. Typhi), the causative agent of typhoid fever, and S. Paratyphi A and B, causative agents of paratyphoid fever, are major…”
Get full text

Impact of oral typhoid vaccination on the human gut microbiota and correlations with s. Typhi-specific immunological responses by Eloe-Fadrosh, Emiley A, McArthur, Monica A, Seekatz, Anna M, Drabek, Elliott F, Rasko, David A, Sztein, Marcelo B, Fraser, Claire M

“…The resident microbial consortia of the human gastrointestinal tract play an integral role in modulating immune responses both locally and systemically…”
Get full text

Role of circulating T follicular helper subsets following Ty21a immunization and oral challenge with wild type S . Typhi in humans by Booth, Jayaum S, Rapaka, Rekha R, McArthur, Monica A, Fresnay, Stephanie, Darton, Thomas C, Blohmke, Christoph J, Jones, Claire, Waddington, Claire S, Levine, Myron M, Pollard, Andrew J, Sztein, Marcelo B

“…Despite decades of intense research, our understanding of the correlates of protection against Typhi ( . Typhi) infection and disease remains incomplete. T…”
Get full text

Activation of Salmonella Typhi-specific regulatory T cells in typhoid disease in a wild-type S. Typhi challenge model by McArthur, Monica A, Fresnay, Stephanie, Magder, Laurence S, Darton, Thomas C, Jones, Claire, Waddington, Claire S, Blohmke, Christoph J, Dougan, Gordon, Angus, Brian, Levine, Myron M, Pollard, Andrew J, Sztein, Marcelo B

“…Salmonella Typhi (S. Typhi), the causative agent of typhoid fever, causes significant morbidity and mortality worldwide. Currently available vaccines are…”
Get full text

Differences Between Pediatric and Adult T Cell Responses to In Vitro Staphylococcal Enterotoxin B Stimulation by Rudolph, Mark E, McArthur, Monica A, Barnes, Robin S, Magder, Laurence S, Chen, Wilbur H, Sztein, Marcelo B

“…Toxic shock syndrome (TSS) is capable of inducing life-threatening fever, rash, and systemic organ failure, though the specific mechanisms behind these…”
Get full text

Characterization of Yellow Fever Virus Infection of Human and Non-human Primate Antigen Presenting Cells and Their Interaction with CD4+ T Cells by Cong, Yu, McArthur, Monica A, Cohen, Melanie, Jahrling, Peter B, Janosko, Krisztina B, Josleyn, Nicole, Kang, Kai, Zhang, Tengfei, Holbrook, Michael R

“…Humans infected with yellow fever virus (YFV), a mosquito-borne flavivirus, can develop illness ranging from a mild febrile disease to hemorrhagic fever and…”
Get full text

Impact of CD4+ T Cell Responses on Clinical Outcome following Oral Administration of Wild-Type Enterotoxigenic Escherichia coli in Humans by McArthur, Monica A, Chen, Wilbur H, Magder, Laurence, Levine, Myron M, Sztein, Marcelo B

“…Enterotoxigenic Escherichia coli (ETEC) is a non-invasive enteric pathogen of considerable public health importance, being one of the most common attributable…”
Get full text

Live Oral Salmonella enterica Serovar Typhi Vaccines Ty21a and CVD 909 Induce Opsonophagocytic Functional Antibodies in Humans That Cross-React with S. Paratyphi A and S. Paratyphi B by Wahid, Rezwanul, Zafar, Shah J, McArthur, Monica A, Pasetti, Marcela F, Levine, Myron M, Sztein, Marcelo B

“…Classifications Services CVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

Age-Associated Heterogeneity of Ty21a-Induced T Cell Responses to HLA-E Restricted Salmonella Typhi Antigen Presentation by Rudolph, Mark E, McArthur, Monica A, Magder, Laurence S, Barnes, Robin S, Chen, Wilbur H, Sztein, Marcelo B

“…Human-restricted serovar Typhi ( . Typhi) is the causative agent of typhoid fever-a life-threatening disease of great global health significance, particularly…”
Get full text

Efficacy and Safety of NVX-CoV2373 in Adults in the United States and Mexico by Dunkle, Lisa M, Kotloff, Karen L, Gay, Cynthia L, Áñez, Germán, Adelglass, Jeffrey M, Barrat Hernández, Alejandro Q, Harper, Wayne L, Duncanson, Daniel M, McArthur, Monica A, Florescu, Diana F, McClelland, R. Scott, Garcia-Fragoso, Veronica, Riesenberg, Robert A, Musante, David B, Fried, David L, Safirstein, Beth E, McKenzie, Mark, Jeanfreau, Robert J, Kingsley, Jeffrey K, Henderson, Jeffrey A, Lane, Dakotah C, Ruíz-Palacios, Guillermo M, Corey, Lawrence, Neuzil, Kathleen M, Coombs, Robert W, Greninger, Alex L, Hutter, Julia, Ake, Julie A, Smith, Katherine, Woo, Wayne, Cho, Iksung, Glenn, Gregory M, Dubovsky, Filip

“…NVX-CoV2373 is a vaccine containing a full-length stabilized recombinant spike protein trimer that is administered in two doses 3 weeks apart along with a…”
Get full text

Dengue vaccines: recent developments, ongoing challenges and current candidates by McArthur, Monica A, Sztein, Marcelo B, Edelman, Robert

“…Dengue is among the most prevalent and important arbovirus diseases of humans. To effectively control this rapidly spreading disease, control of the vector…”
Get more information

SARS‐CoV‐2 infection in pediatric patient with hemoglobin SC disease by Dagalakis, Urania, Hammershaimb, Elizabeth, McArthur, Monica A., Macatangay, Regina A.

Get full text

Human immune responses against Shigella and enterotoxigenic E. coli : Current advances and the path forward by McArthur, Monica A, Maciel, Milton, Pasetti, Marcela F

“…Abstract Robust and well-established immunological assays and firm immune correlates of protection that can predict disease outcome and/or vaccine efficacy are…”
Get full text

A Promising, Single-Dose, Live Attenuated Tetravalent Dengue Vaccine Candidate by McArthur, Monica A., Edelman, Robert

Get full text

Role of antigen specific T and B cells in systemic and mucosal immune responses in ETEC and Shigella infections, and their potential to serve as correlates of protection in vaccine development by Mani, Sachin, Toapanta, Franklin R., McArthur, Monica A., Qadri, Firdausi, Svennerholm, Ann-Mari, Devriendt, Bert, Phalipon, Armelle, Cohen, Daniel, Sztein, Marcelo B.

“…The generation of robust systemic and mucosal antibody and cell-mediated immune (CMI) responses that are protective, long-lasting, and can quickly be recalled…”
Get full text

Salmonella Typhi-specific multifunctional CD8+ T cells play a dominant role in protection from typhoid fever in humans by Fresnay, Stephanie, McArthur, Monica A, Magder, Laurence, Darton, Thomas C, Jones, Claire, Waddington, Claire S, Blohmke, Christoph J, Angus, Brian, Levine, Myron M, Pollard, Andrew J, Sztein, Marcelo B

“…Typhoid fever, caused by the human-restricted organism Salmonella Typhi (S. Typhi), is a major public health problem worldwide. Development of novel vaccines…”
Get full text

Diversity of Salmonella Typhi-responsive CD4 and CD8 T cells before and after Ty21a typhoid vaccination in children and adults by Rudolph, Mark E, McArthur, Monica A, Magder, Laurence S, Barnes, Robin S, Chen, Wilbur H, Sztein, Marcelo B

“…Typhoid fever is a life-threatening disease caused by the human-restricted pathogen Salmonella enterica serovar Typhi (S. Typhi). The oral live attenuated…”
Get full text