Search Results - "McArdle, CA"

THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: G protein‐coupled receptors by Alexander, Stephen PH, Davenport, Anthony P, Peters, John A, Veale, Emma L, Faccenda, Elena, Harding, Simon D, Pawson, Adam J, Sharman, Joanna L, Southan, Christopher, Abbracchio, Maria P, Alexander, Wayne, Al-hosaini, Khaled, Bäck, Magnus, Beaulieu, Jean‐Martin, Bernstein, Kenneth E., Birdsall, Nigel JM, Blaho, Victoria, Bousquet, Corinne, Caló, Girolamo, Ceruti, Stefania, Chazot, Paul, Chiang, Nan, Chun, Jerold, Cianciulli, Antonia, Clapp, Lucie H, Couture, Réjean, Dent, Gordon, Douglas, Steven D, Dournaud, Pascal, Eguchi, Satoru, Filardo, Edward, Fong, Tung M, Fumagalli, Marta, Gainetdinov, Raul R, Gasparo, Marc de, Goudet, Cyril, Gregory, Karen J, Hamann, Jörg, Hauger, Richard L, Heinemann, Akos, Holliday, Nicholas D, Horiuchi, Mastgugu, Husain, Ahsan, Inagami, Tadashi, Jacobson, Kenneth A, Jensen, Robert T, Jockers, Ralf, Jonnalagadda, Deepa, Kemp, Jacqueline, Kennedy, Charles, Kihara, Yasuyuki, Kukkonen, Jyrki P, Leach, Katie, Lecca, Davide, Lee, John D, Leeman, Susan E, Leprince, Jérôme, Lolait, Stephen J, Lupp, Amelie, Macrae, Robyn, Mazella, Jean, McArdle, Craig A, Melmed, Shlomo, Michel, Martin C, Miller, Laurence, Mitolo, Vincenzo, Mouillac, Bernard, Murphy, Philip M, Nahon, Jean‐Louis, Norel, Xavier, Nyimanu, Duuamene, O'Carroll, Anne‐Marie, Panaro, Maria A, Pertwee, Roger G, Pin, Jean‐Philippe, Prossnitz, Eric, Rovati, G Enrico, Ruzza, Chiara, Sanger, Gareth, Schöneberg, Torsten, Schulte, Gunnar, Serhan, Charles N, Stoddart, Leigh A, Sugimoto, Yukihiko, Summers, Roger, Tan, Valerie, Thomas, Walter, Tirupula, Kalyan, Tulipano, Giovanni, Unal, Hamiyet, Unger, Thomas, Vanderheyden, Patrick, Vilardaga, Jean‐Pierre, Walker, Christopher S, Ward, Donald T, Wester, Hans‐Jürgen, Willars, Gary B, Williams, Tom Lloyd, Woodruff, Trent M, Yao, Chengcan

“…The Concise Guide to PHARMACOLOGY 2019/20 is the fourth in this series of biennial publications. The Concise Guide provides concise overviews of the key…”
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Signalling, cycling and desensitisation of gonadotrophin-releasing hormone receptors by McArdle, CA, Franklin, J, Green, L, Hislop, JN

“…Sustained stimulation of G-protein-coupled receptors (GPCRs) typically causes receptor desensitisation, which is mediated by phosphorylation, often within the…”
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The Concise Guide to PHARMACOLOGY 2023/24: G protein-coupled receptors by Armstrong, Jane F., Faccenda, Elena, Davies, Jamie A., Abraham, George, Alexander, Wayne, Al‐hosaini, Khaled, Bäck, Magnus, Barnes, Nicholas M., Beck‐Sickinger, Annette G., Behrens, Maik, Bettler, Bernhard, Birdsall, Nigel J. M., Bräuner‐Osborne, Hans, Burnstock, Geoffrey, Castaño, Justo P., Ceruti, Stefania, Chazot, Paul, Chiang, Nan, Chun, Jerold, Cianciulli, Antonia, Clapp, Lucie H., Couture, Réjean, Cox, Helen M., Csaba, Zsolt, Dahlgren, Claes, Dent, Gordon, Eguchi, Satoru, Escher, Emanuel, Filardo, Edward J., Fong, Tung, Fumagalli, Marta, Gasparo, Marc, Gerard, Craig, Gershengorn, Marvin, Goudet, Cyril, Grätz, Lukas, Gregory, Karen J., Gundlach, Andrew L., Hamann, Jörg, Hay, Debbie L., Heinemann, Akos, Herr, Deron, Hollenberg, Morley D., Holliday, Nicholas D., Hunyady, László, Husain, Ahsan, IJzerman, Adriaan P., Inagami, Tadashi, Jacobson, Kenneth A., Jockers, Ralf, Jonnalagadda, Deepa, Karnik, Sadashiva, Kennedy, Charles, Kitazawa, Takio, Kukkonen, Jyrki P., Larhammar, Dan, Leach, Katie, Lee, John D., Lolait, Stephen J., Macrae, Robyn, Maguire, Janet, Malfacini, Davide, McArdle, Craig A., Michel, Martin C., Mouillac, Bernard, Müller, Christa E., Ngo, Tony, Nyimanu, Duuamene, O’Carroll, Anne‐Marie, Offermanns, Stefan, Panaro, Maria Antonietta, Pertwee, Roger G., Pin, Jean‐Philippe, Prossnitz, Eric R., Quinn, Mark, Ray, Manisha, Rondard, Philippe, Rovati, G. Enrico, Schöneberg, Torsten, Schulte, Gunnar, Segaloff, Deborah L., Singh, Khuraijam Dhanachandra, Stoddart, Leigh A., Sugimoto, Yukihiko, Summers, Roger, Thal, David, Thomas, Walter ( Wally), Timmermans, Pieter B. M. W. M., Tirupula, Kalyan, Toll, Lawrence, Tulipano, Giovanni, Unal, Hamiyet, Valant, Celine, Vaudry, Hubert, Vilardaga, Jean‐Pierre, Wang, Ji Ming, Ward, Donald T., Willars, Gary B., Williams, Tom Lloyd, Woodruff, Trent M.

“…The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular…”
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The Concise Guide to PHARMACOLOGY 2015/16: Enzymes by Alexander, Stephen PH, Fabbro, Doriano, Kelly, Eamonn, Marrion, Neil, Peters, John A, Benson, Helen E, Faccenda, Elena, Pawson, Adam J, Sharman, Joanna L, Southan, Christopher, Davies, Jamie A

“…The Concise Guide to PHARMACOLOGY 2015/16 provides concise overviews of the key properties of over 1750 human drug targets with their pharmacology, plus links…”
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The Concise Guide to PHARMACOLOGY 2015/16: G protein‐coupled receptors by Alexander, Stephen PH, Davenport, Anthony P, Kelly, Eamonn, Marrion, Neil, Peters, John A, Benson, Helen E, Faccenda, Elena, Pawson, Adam J, Sharman, Joanna L, Southan, Christopher, Davies, Jamie A

“…The Concise Guide to PHARMACOLOGY 2015/16 provides concise overviews of the key properties of over 1750 human drug targets with their pharmacology, plus links…”
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The Concise Guide to PHARMACOLOGY 2015/16: Transporters by Alexander, Stephen PH, Kelly, Eamonn, Marrion, Neil, Peters, John A, Benson, Helen E, Faccenda, Elena, Pawson, Adam J, Sharman, Joanna L, Southan, Christopher, Davies, Jamie A

“…The Concise Guide to PHARMACOLOGY 2015/16 provides concise overviews of the key properties of over 1750 human drug targets with their pharmacology, plus links…”
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The Concise Guide to PHARMACOLOGY 2015/16: Voltage‐gated ion channels by Alexander, Stephen PH, Catterall, William A, Kelly, Eamonn, Marrion, Neil, Peters, John A, Benson, Helen E, Faccenda, Elena, Pawson, Adam J, Sharman, Joanna L, Southan, Christopher, Davies, Jamie A

“…The Concise Guide to PHARMACOLOGY 2015/16 provides concise overviews of the key properties of over 1750 human drug targets with their pharmacology, plus links…”
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The Concise Guide to PHARMACOLOGY 2015/16: Catalytic receptors by Alexander, Stephen PH, Fabbro, Doriano, Kelly, Eamonn, Marrion, Neil, Peters, John A, Benson, Helen E, Faccenda, Elena, Pawson, Adam J, Sharman, Joanna L, Southan, Christopher, Davies, Jamie A

“…The Concise Guide to PHARMACOLOGY 2015/16 provides concise overviews of the key properties of over 1750 human drug targets with their pharmacology, plus links…”
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The Concise Guide to PHARMACOLOGY 2015/16: Ligand‐gated ion channels by Alexander, Stephen PH, Peters, John A, Kelly, Eamonn, Marrion, Neil, Benson, Helen E, Faccenda, Elena, Pawson, Adam J, Sharman, Joanna L, Southan, Christopher, Davies, Jamie A

“…The Concise Guide to PHARMACOLOGY 2015/16 provides concise overviews of the key properties of over 1750 human drug targets with their pharmacology, plus links…”
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The Concise Guide to PHARMACOLOGY 2015/16: Nuclear hormone receptors by Alexander, Stephen PH, Cidlowski, John A, Kelly, Eamonn, Marrion, Neil, Peters, John A, Benson, Helen E, Faccenda, Elena, Pawson, Adam J, Sharman, Joanna L, Southan, Christopher, Davies, Jamie A

“…The Concise Guide to PHARMACOLOGY 2015/16 provides concise overviews of the key properties of over 1750 human drug targets with their pharmacology, plus links…”
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Signalling and anti-proliferative effects mediated by gonadotrophin-releasing hormone receptors after expression in prostate cancer cells using recombinant adenovirus by Franklin, J, Hislop, J, Flynn, A, McArdle, CA

“…Gonadotrophin-releasing hormone receptors (GnRH-Rs) are found in cancers of reproductive tissues, including those of the prostate, and gonadotrophin-releasing…”
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The Concise Guide to PHARMACOLOGY 2015/16: Other ion channels by Alexander, Stephen PH, Kelly, Eamonn, Marrion, Neil, Peters, John A, Benson, Helen E, Faccenda, Elena, Pawson, Adam J, Sharman, Joanna L, Southan, Christopher, Davies, Jamie A

“…The Concise Guide to PHARMACOLOGY 2015/16 provides concise overviews of the key properties of over 1750 human drug targets with their pharmacology, plus links…”
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Encoding and Decoding Mechanisms of Pulsatile Hormone Secretion by Walker, J. J., Terry, J. R., Tsaneva-Atanasova, K., Armstrong, S. P., McArdle, C. A., Lightman, S. L.

“…Ultradian pulsatile hormone secretion underlies the activity of most neuroendocrine systems, including the hypothalamic‐pituitary adrenal (HPA) and gonadal…”
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Involvement of PKCα and G‐protein‐coupled receptor kinase 2 in agonist‐selective desensitization of µ‐opioid receptors in mature brain neurons by Bailey, CP, Oldfield, S, Llorente, J, Caunt, CJ, Teschemacher, AG, Roberts, L, McArdle, CA, Smith, FL, Dewey, WL, Kelly, E, Henderson, G

“…Background and purpose:  The ability of an agonist to induce desensitization of the µ‐opioid receptor (MOR) depends upon the agonist used. Furthermore,…”
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C-type natriuretic peptide (CNP) effects in anterior pituitary cell lines: evidence for homologous desensitisation of CNP-stimulated cGMP accumulation in alpha T3-1 gonadotroph-derived cells by Fowkes, RC, Forrest-Owen, W, McArdle, CA

“…C-type natriuretic peptide (CNP), the third member of the natriuretic peptide family, has been found at its highest tissue concentrations in the anterior…”
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Arrestin-mediated ERK activation by gonadotropin-releasing hormone receptors: receptor-specific activation mechanisms and compartmentalization by Caunt, Christopher J, Finch, Ann R, Sedgley, Kathleen R, Oakley, Lisa, Luttrell, Louis M, McArdle, Craig A

“…Activation of seven-transmembrane region receptors typically causes their phosphorylation with consequent arrestin binding and desensitization. Arrestins also…”
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Trafficking and signalling of gonadotrophin‐releasing hormone receptors: an automated imaging approach by Finch, AR, Sedgley, KR, Armstrong, SP, Caunt, CJ, McArdle, CA

“…Gonadotrophin‐releasing hormone (GnRH) is a neuropeptide that mediates central control of reproduction by stimulating gonadotrophin secretion from the…”
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Using automated imaging to interrogate gonadotrophin-releasing hormone receptor trafficking and function by Armstrong, S.P., Caunt, C.J., Finch, A.R., McArdle, C.A.

“…Gonadotrophin-releasing hormone (GnRH) acts via seven transmembrane receptors on gonadotrophs to stimulate gonadotrophin synthesis and secretion, and thereby…”
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Internalization and Desensitization of the Oxytocin Receptor Is Inhibited by Dynamin and Clathrin Mutants in Human Embryonic Kidney 293 Cells by Smith, M. P, Ayad, V. J, Mundell, S. J, McArdle, C. A, Kelly, E, López Bernal, A

“…Oxytocin (OT) has long been used as an uterotonic during labor management in women, and yet responses to OT infusion remain variable and unpredictable among…”
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Potential use of an estrogen–glucocorticoid receptor chimera as a drug screen for tissue selective estrogenic activity by Maru, Benit S, Tobias, Jonathan H, Rivers, Caroline, Caunt, Christopher J, Norman, Michael R, McArdle, Craig A

“…Abstract SERMs act as ER agonists in bone despite their antagonistic properties in other tissues. As well as inhibiting bone remodelling, this effect may…”
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