Search Results - "McArdle, Andrew"
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When do co-infections matter?
Published in Current opinion in infectious diseases (01-06-2018)“…PURPOSE OF REVIEWAdvances in diagnostic methods mean that co-infections are increasingly being detected in clinical practice, yet their significance is not…”
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Determinants of Carboxyhemoglobin Levels and Relationship with Sepsis in a Retrospective Cohort of Preterm Neonates
Published in PloS one (23-08-2016)“…Carboxyhemoglobin levels in blood reflect endogenous carbon monoxide production and are often measured during routine blood gas analysis. Endogenous carbon…”
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A proteomics-based method for identifying antigens within immune complexes
Published in PloS one (23-12-2020)“…A novel approach to recover and identify immune complexes (ICs) was developed using size exclusion chromatography (SEC) and affinity chromatography on…”
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Therapy for Multisystem Inflammatory Syndrome in Children. Reply
Published in The New England journal of medicine (23-09-2021)Get full text
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Immunomodulatory Therapy for MIS-C
Published in Pediatrics (Evanston) (01-07-2023)“…Studies comparing initial therapy for multisystem inflammatory syndrome in children (MIS-C) provided conflicting results. To compare outcomes in MIS-C patients…”
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Developmentally regulated expression, alternative splicing and distinct sub-groupings in members of the Schistosoma mansoni venom allergen-like (SmVAL) gene family
Published in BMC genomics (23-02-2008)“…The Sperm-coating protein/Tpx-1/Ag5/PR-1/Sc7 (SCP/TAPS) domain is found across phyla and is a major structural feature of insect allergens, mammalian sperm…”
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Sensitivity of shotgun metagenomics to host DNA: abundance estimates depend on bioinformatic tools and contamination is the main issue
Published in Access microbiology (2020)“…A recent study reported that increasing host DNA abundance and reducing read depth impairs the sensitivity of detection of low-abundance micro-organisms by…”
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The immunopathogenesis of SARS‐CoV‐2 infection in children: diagnostics, treatment and prevention
Published in Clinical & translational immunology (2022)“…Symptoms and outcomes for paediatric COVID‐19 differ vastly from those for adults, with much lower morbidity and mortality. Immunopathogenesis drives severe…”
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Kawasaki Disease Patient Stratification and Pathway Analysis Based on Host Transcriptomic and Proteomic Profiles
Published in International journal of molecular sciences (26-05-2021)“…The aetiology of Kawasaki disease (KD), an acute inflammatory disorder of childhood, remains unknown despite various triggers of KD having been proposed. Host…”
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Hypervitaminosis A is prevalent in children with CKD and contributes to hypercalcemia
Published in Pediatric nephrology (Berlin, West) (01-02-2015)“…Background Vitamin A accumulates in renal failure, but the prevalence of hypervitaminosis A in children with predialysis chronic kidney disease (CKD) is not…”
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Treatment of Multisystem Inflammatory Syndrome in Children: Understanding Differences in Results of Comparative Effectiveness Studies
Published in ACR open rheumatology (01-09-2022)“…Objective Two cohort studies in patients with multisystem inflammatory syndrome in children (MIS‐C) demonstrated contrasting results regarding the benefit of…”
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Use of genomic DNA as an indirect reference for identifying gender-associated transcripts in morphologically identical, but chromosomally distinct, Schistosoma mansoni cercariae
Published in PLoS neglected tropical diseases (01-10-2008)“…The use of DNA microarray technology to study global Schistosoma gene expression has led to the rapid identification of novel biological processes, pathways or…”
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Short-term and medium-term clinical outcomes of multisystem inflammatory syndrome in children: a prospective observational cohort study
Published in Italian journal of pediatrics (04-01-2024)“…Even though the incidence of Multisystem Inflammatory Syndrome in children (MIS-C) is decreasing cases are still reported across the world. Studying the…”
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Question 2: Is the packed cell volume ÷ 3 rule valid for estimating haemoglobin in children in malarious areas?
Published in Archives of disease in childhood (01-03-2018)“…Outcomes may be improved if severe anaemia is correctly diagnosed and treated with blood transfusion and evidence shows poorer outcomes when transfusions are…”
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When do coinfections matter?
Published in Current opinion in infectious diseases (22-03-2018)“…PURPOSE OF REVIEWAdvances in diagnostic methods mean that coinfections are increasingly being detected in clinical practice, yet their significance is not…”
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Therapy for Multisystem Inflammatory Syndrome in Children
Published in The New England journal of medicine (23-09-2021)“…To the Editor: McArdle et al. (July 1 issue) reviewed the available data on the treatment of multisystem inflammatory syndrome in children (MIS-C), also…”
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Characterisation of immune complexes in Kawasaki Disease and other infectious diseases by protein sequencing
Published in The Journal of immunology (1950) (01-05-2019)“…Abstract Background Kawasaki Disease is a paediatric inflammatory disease associated with self-limiting vasculitis. It has a world-wide distribution with an…”
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