Search Results - "McAndrew, Erin N."

The enigmatic oncogene and tumor suppressor‐like properties of RAD54B: Insights into genome instability and cancer by McAndrew, Erin N., McManus, Kirk J.

“…One of the major challenges to the cell is to ensure genome stability, which can be compromised through endogenous errors or exogenous DNA damaging agents,…”
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Long-term Survival Among Patients With De Novo Human Epidermal Growth Receptor 2-Positive Metastatic Breast Cancer in Manitoba by McAndrew, Erin N, Graham, Jeffrey, Dufault, Brenden, Desautels, Danielle N, Kim, Christina A

“…Although metastatic breast cancer (MBC) is considered incurable, human epidermal growth receptor 2 (HER2)-directed therapy has improved outcomes significantly,…”
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Treatment Patterns, Toxicity, and Outcomes of Older Adults With Advanced Pancreatic Cancer Receiving First-line Palliative Chemotherapy by McAndrew, Erin N., Zhang, Hanbo, Lambert, Pascal, Rittberg, Rebekah, Dawe, David E., Kim, Christina A.

“…Advanced pancreatic cancer (APC) disproportionately impacts older adults. Randomized trials demonstrate improved overall survival (OS) with combination…”
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The synthetic lethal killing of RAD54B-deficient colorectal cancer cells by PARP1 inhibition is enhanced with SOD1 inhibition by McAndrew, Erin N, Lepage, Chloe C, McManus, Kirk J

“…Colorectal cancer (CRC) is a leading cause of cancer-related death throughout the world. Despite improved screening efforts, most CRCs are diagnosed at late…”
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Capecitabine-mediated heart failure in colorectal cancer: a case series by McAndrew, Erin N, Jassal, Davinder S, Goldenberg, Benjamin A, Kim, Christina A

“…Abstract Background Capecitabine is a pyrimidine antimetabolite that inhibits thymidylate synthase and is commonly used in the treatment of colorectal cancer…”
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Treatment Patterns, Toxicity, and Outcomes of Older Adults With Advanced Pancreatic Cancer Receiving First-line Palliative Chemotherapy by McAndrew, Erin N., Zhang, Hanbo, Lambert, Pascal, Rittberg, Rebekah, Dawe, David E., Kim, Christina A.

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Abstract 2744: Synthetic lethal killing of RAD54B-deficient cancer cells by PARP1 silencing and inhibition by McAndrew, Erin N., Lepage, Chloe C., McManus, Kirk J.

“…Abstract Colorectal Cancer (CRC) is the second leading cause of cancer-related deaths in North America. Currently, many chemotherapeutics are non-specific and…”
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