Search Results - "McAnarney, Eileen"

Trypsin Treatment Unlocks Barrier for Zoonotic Bat Coronavirus Infection by Menachery, Vineet D, Dinnon, 3rd, Kenneth H, Yount, Jr, Boyd L, McAnarney, Eileen T, Gralinski, Lisa E, Hale, Andrew, Graham, Rachel L, Scobey, Trevor, Anthony, Simon J, Wang, Lingshu, Graham, Barney, Randell, Scott H, Lipkin, W Ian, Baric, Ralph S

“…Traditionally, the emergence of coronaviruses (CoVs) has been attributed to a gain in receptor binding in a new host. Our previous work with severe acute…”
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MERS-CoV Accessory ORFs Play Key Role for Infection and Pathogenesis by Menachery, Vineet D, Mitchell, Hugh D, Cockrell, Adam S, Gralinski, Lisa E, Yount, Jr, Boyd L, Graham, Rachel L, McAnarney, Eileen T, Douglas, Madeline G, Scobey, Trevor, Beall, Anne, Dinnon, 3rd, Kenneth, Kocher, Jacob F, Hale, Andrew E, Stratton, Kelly G, Waters, Katrina M, Baric, Ralph S

“…While dispensable for viral replication, coronavirus (CoV) accessory open reading frame (ORF) proteins often play critical roles during infection and…”
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Combination Attenuation Offers Strategy for Live Attenuated Coronavirus Vaccines by Menachery, Vineet D, Gralinski, Lisa E, Mitchell, Hugh D, Dinnon, 3rd, Kenneth H, Leist, Sarah R, Yount, Jr, Boyd L, McAnarney, Eileen T, Graham, Rachel L, Waters, Katrina M, Baric, Ralph S

“…With an ongoing threat posed by circulating zoonotic strains, new strategies are required to prepare for the next emergent coronavirus (CoV). Previously,…”
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Endomembrane targeting of human OAS1 p46 augments antiviral activity by Soveg, Frank W, Schwerk, Johannes, Gokhale, Nandan S, Cerosaletti, Karen, Smith, Julian R, Pairo-Castineira, Erola, Kell, Alison M, Forero, Adriana, Zaver, Shivam A, Esser-Nobis, Katharina, Roby, Justin A, Hsiang, Tien-Ying, Ozarkar, Snehal, Clingan, Jonathan M, McAnarney, Eileen T, Stone, Amy El, Malhotra, Uma, Speake, Cate, Perez, Joseph, Balu, Chiraag, Allenspach, Eric J, Hyde, Jennifer L, Menachery, Vineet D, Sarkar, Saumendra N, Woodward, Joshua J, Stetson, Daniel B, Baillie, John Kenneth, Buckner, Jane H, Gale, Jr, Michael, Savan, Ram

“…Many host RNA sensors are positioned in the cytosol to detect viral RNA during infection. However, most positive-strand RNA viruses replicate within a modified…”
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Topoisomerase III-β is required for efficient replication of positive-sense RNA viruses by Prasanth, K. Reddisiva, Hirano, Minato, Fagg, W. Samuel, McAnarney, Eileen T., Shan, Chao, Xie, Xuping, Hage, Adam, Pietzsch, Colette A., Bukreyev, Alexander, Rajsbaum, Ricardo, Shi, Pei-Yong, Bedford, Mark T., Bradrick, Shelton S., Menachery, Vineet, Garcia-Blanco, Mariano A.

“…Based on genome-scale loss-of-function screens we discovered that Topoisomerase III-β (TOP3B), a human topoisomerase that acts on DNA and RNA, is required for…”
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Nucleosome conformation dictates the histone code by Marunde, Matthew R, Fuchs, Harrison A, Burg, Jonathan M, Popova, Irina K, Vaidya, Anup, Hall, Nathan W, Weinzapfel, Ellen N, Meiners, Matthew J, Watson, Rachel, Gillespie, Zachary B, Taylor, Hailey F, Mukhsinova, Laylo, Onuoha, Ugochi C, Howard, Sarah A, Novitzky, Katherine, McAnarney, Eileen T, Krajewski, Krzysztof, Cowles, Martis W, Cheek, Marcus A, Sun, Zu-Wen, Venters, Bryan J, Keogh, Michael-C, Musselman, Catherine A

“…Histone post-translational modifications (PTMs) play a critical role in chromatin regulation. It has been proposed that these PTMs form localized 'codes' that…”
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Middle East Respiratory Syndrome Coronavirus Nonstructural Protein 16 Is Necessary for Interferon Resistance and Viral Pathogenesis by Menachery, Vineet D, Gralinski, Lisa E, Mitchell, Hugh D, Dinnon, 3rd, Kenneth H, Leist, Sarah R, Yount, Jr, Boyd L, Graham, Rachel L, McAnarney, Eileen T, Stratton, Kelly G, Cockrell, Adam S, Debbink, Kari, Sims, Amy C, Waters, Katrina M, Baric, Ralph S

“…Coronaviruses (CoVs) encode a mixture of highly conserved and novel genes, as well as genetic elements necessary for infection and pathogenesis, raising the…”
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Age-dependent Susceptibility To Virus Infection Is Governed by Host Genetics by Menachery, Vineet D, McAnarney, Eileen T, Ferris, Martin T

“…While improved sanitation and medical care have reduced the burden of infectious disease, it remains the 4th leading cause of death in the elderly. Coupled…”
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A ChIP-exo screen of 887 Protein Capture Reagents Program transcription factor antibodies in human cells by Lai, William K M, Mariani, Luca, Rothschild, Gerson, Smith, Edwin R, Venters, Bryan J, Blanda, Thomas R, Kuntala, Prashant K, Bocklund, Kylie, Mairose, Joshua, Dweikat, Sarah N, Mistretta, Katelyn, Rossi, Matthew J, James, Daniela, Anderson, James T, Phanor, Sabrina K, Zhang, Wanwei, Zhao, Zibo, Shah, Avani P, Novitzky, Katherine, McAnarney, Eileen, Keogh, Michael-C, Shilatifard, Ali, Basu, Uttiya, Bulyk, Martha L, Pugh, B Franklin

“…Antibodies offer a powerful means to interrogate specific proteins in a complex milieu. However, antibody availability and reliability can be problematic,…”
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