Search Results - "McAlonan, Grainne M."

Effects of cannabidiol on brain excitation and inhibition systems; a randomised placebo-controlled single dose trial during magnetic resonance spectroscopy in adults with and without autism spectrum disorder by Pretzsch, Charlotte Marie, Freyberg, Jan, Voinescu, Bogdan, Lythgoe, David, Horder, Jamie, Mendez, Maria Andreina, Wichers, Robert, Ajram, Laura, Ivin, Glynis, Heasman, Martin, Edden, Richard A E, Williams, Steven, Murphy, Declan G M, Daly, Eileen, McAlonan, Gráinne M

“…There is increasing interest in the use of cannabis and its major non-intoxicating component cannabidiol (CBD) as a treatment for mental health and…”
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Frontal and occipital brain glutathione levels are unchanged in autistic adults by Pereira, Andreia C, Leonard, Alison, Velthuis, Hester, Wong, Nichol M L, Ponteduro, Francesca M, Dimitrov, Mihail, Ellis, Claire L, Kowalewski, Lukasz, Lythgoe, David J, Rotaru, Diana-Georgina, Edden, Richard A E, Ivin, Glynis, Pretzsch, Charlotte M, Daly, Eileen, Murphy, Declan G M, McAlonan, Gráinne M

“…The neurobiological underpinnings of Autism Spectrum Disorder (ASD) are diverse and likely multifactorial. One possible mechanism is increased oxidative stress…”
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Autism spectrum disorder in adults: diagnosis, management, and health services development by Murphy, Clodagh M, Wilson, C Ellie, Robertson, Dene M, Ecker, Christine, Daly, Eileen M, Hammond, Neil, Galanopoulos, Anastasios, Dud, Iulia, Murphy, Declan G, McAlonan, Grainne M

“…Autism spectrum disorder (ASD) is a common neurodevelopmental disorder characterized by pervasive difficulties since early childhood across reciprocal social…”
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The contribution of [1H] magnetic resonance spectroscopy to the study of excitation-inhibition in autism by Ajram, Laura A., Pereira, Andreia C., Durieux, Alice M.S., Velthius, Hester E., Petrinovic, Marija M., McAlonan, Grainne M.

“…Autism spectrum disorder (ASD) affects over 1:100 of the population and costs the UK more than £32bn and the USA more than $175bn (£104bn) annually. Its core…”
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Neural Acupuncture Unit: A New Concept for Interpreting Effects and Mechanisms of Acupuncture by Zhang, Zhang-Jin, McAlonan, Grainne M., Wang, Xiao-Min

“…When an acupuncture needle is inserted into a designated point on the body and mechanical or electrical stimulation is delivered, various neural and…”
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Can Asperger syndrome be distinguished from autism? An anatomic likelihood meta-analysis of MRI studies by Yu, Kevin K., BSc, Cheung, Charlton, PhD, Chua, Siew E., BM BCh, McAlonan, Gráinne M., MBBS, PhD

“…Background The question of whether Asperger syndrome can be distinguished from autism has attracted much debate and may even incur delay in diagnosis and…”
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Simultaneous quantification of GABA, Glx and GSH in the neonatal human brain using magnetic resonance spectroscopy by Yanez Lopez, Maria, Price, Anthony N., Puts, Nicolaas A.J., Hughes, Emer J., Edden, Richard A.E., McAlonan, Grainne M., Arichi, Tomoki, De Vita, Enrico

“…•First simultaneous measurement of GABA+, Glx and GSH in the neonatal human brain.•Robust metabolic estimation in neonates requires a specific quantification…”
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Stress and Psychological Distress among SARS Survivors 1 Year after the Outbreak by Lee, Antoinette M, Wong, Josephine GWS, McAlonan, Grainne M, Cheung, Vinci, Cheung, Charlton, Sham, Pak C, Chu, Chung-Ming, Wong, Poon-Chuen, Tsang, Kenneth WT, Chua, Siew E

“…Objective: Our study examined the stress level and psychological distress of severe acute respiratory syndrome (SARS) survivors 1 year after the outbreak…”
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The 'PSILAUT' protocol: an experimental medicine study of autistic differences in the function of brain serotonin targets of psilocybin by Whelan, Tobias P, Daly, Eileen, Puts, Nicolaas A, Smith, Paula, Allison, Carrie, Baron-Cohen, Simon, Malievskaia, Ekaterina, Murphy, Declan G M, McAlonan, Grainne M

“…The underlying neurobiology of the complex autism phenotype remains obscure, although accumulating evidence implicates the serotonin system and especially the…”
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Neurometabolite mapping highlights elevated myo-inositol profiles within the developing brain in down syndrome by Patkee, Prachi A., Baburamani, Ana A., Long, Katherine R., Dimitrova, Ralica, Ciarrusta, Judit, Allsop, Joanna, Hughes, Emer, Kangas, Johanna, McAlonan, Grainne M., Rutherford, Mary A., De Vita, Enrico

“…The neurodevelopmental phenotype in Down Syndrome (DS), or Trisomy 21, is variable including a wide spectrum of cognitive impairment and a high risk of…”
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Immediate and Sustained Psychological Impact of an Emerging Infectious Disease Outbreak on Health Care Workers by McAlonan, Grainne M, Lee, Antoinette M, Cheung, Vinci, Cheung, Charlton, Tsang, Kenneth WT, Sham, Pak C, Chua, Siew E, Wong, Josephine GWS

“…Objective: To assess the immediate and sustained psychological health of health care workers who were at high risk of exposure during the severe acute…”
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Prenatal immune challenge is an environmental risk factor for brain and behavior change relevant to schizophrenia: evidence from MRI in a mouse model by Li, Qi, Cheung, Charlton, Wei, Ran, Hui, Edward S, Feldon, Joram, Meyer, Urs, Chung, Sookja, Chua, Siew E, Sham, Pak C, Wu, Ed X, McAlonan, Grainne M

“…Maternal infection during pregnancy increases risk of severe neuropsychiatric disorders, including schizophrenia and autism, in the offspring. The most…”
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Cerebral grey, white matter and csf in never-medicated, first-episode schizophrenia by Chua, Siew E, Cheung, Charlton, Cheung, Vinci, Tsang, Jack T.K, Chen, Eric Y.H, Wong, Jason C.H, Cheung, Jason P.Y, Yip, Lawrance, Tai, Kin-shing, Suckling, John, McAlonan, Gráinne M

“…Abstract We report the first voxel-based morphometric (VBM) study to examine cerebral grey and white matter and cerebrospinal fluid (CSF) using computational…”
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MR diffusion tensor imaging detects rapid microstructural changes in amygdala and hippocampus following fear conditioning in mice by Ding, Abby Y, Li, Qi, Zhou, Iris Y, Ma, Samantha J, Tong, Gehua, McAlonan, Grainne M, Wu, Ed X

“…Following fear conditioning (FC), ex vivo evidence suggests that early dynamics of cellular and molecular plasticity in amygdala and hippocampal circuits…”
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Comparison of an online adaptation of the Autism Diagnostic Observation Schedule-2 with its in-person version in an adult autism diagnostic service by Blackmore, Charlotte E., Nolan, Alexandra, Stoencheva, Vladimira, Greenwood, Natalie, Liu-Thwaites, Natasha, Maltezos, Stefanos, McAlonan, Grainne M.

“…Restrictions on in-person assessments during the COVID-19 pandemic were a challenge for an adult autism diagnostic service receiving over 600 referrals…”
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Abnormal spatiotemporal processing of emotional facial expressions in childhood autism: dipole source analysis of event-related potentials by Wong, Teresa K. W., Fung, Peter C. W., Chua, Siew E., McAlonan, Grainne M.

“…Previous studies of face processing in autism suggest abnormalities in anatomical development, functioning and connectivity/coordination of distributed brain…”
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LINE1 and Mecp2 methylation of the adult striatum and prefrontal cortex exposed to prenatal immune activation by Basil, Paul, Li, Qi, Sham, Pak-Chung, McAlonan, Grainne M.

“…Prenatal exposure to infection and inflammation increases the risk of neurodevelopmental disorders such as schizophrenia and autism. The etiology could be…”
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Genome-wide DNA methylation data from adult brain following prenatal immune activation and dietary intervention by Basil, Paul, Li, Qi, McAlonan, Grainne M., Sham, Pak-Chung

“…DNA methylation is a dynamic epigenetic mark regulating gene function and are implicated in the pathophysiology of schizophrenia and autism. Environmental…”
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Father-infant interactions and infant regional brain volumes: A cross-sectional MRI study by Sethna, Vaheshta, Siew, Jasmine, Pote, Inês, Wang, Siying, Gudbrandsen, Maria, Lee, Charlotte, Perry, Emily, Adams, Kerrie P.H., Watson, Clare, Kangas, Johanna, Stoencheva, Vladimira, Daly, Eileen, Kuklisova-Murgasova, Maria, Williams, Steven C.R., Craig, Michael C., Murphy, Declan G.M., McAlonan, Grainne M.

“…Fathers play a crucial role in their children’s socio-emotional and cognitive development. A plausible intermediate phenotype underlying this association is…”
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Psychological Effects of the SARS Outbreak in Hong Kong on High-Risk Health Care Workers by Chua, Siew E, Cheung, Vinci, Cheung, Charlton, McAlonan, Grainne M, Wong, Josephine WS, Cheung, Erik PT, Chan, Marco TY, Wong, Michael MC, Tang, Siu W, Choy, Khai M, Wong, Meng K, Chu, Chung M, Tsang, Kenneth WT

“…Objective: To quantify stress and the psychological impact of severe acute respiratory syndrome (SARS) on high-risk health care workers (HCWs). Method: We…”
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