Search Results - "Mc Larney, Benedict"
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Optoacoustic Calcium Imaging of Deep Brain Activity in an Intracardially Perfused Mouse Brain Model
Published in Photonics (01-06-2019)“…One main limitation of established neuroimaging methods is the inability to directly visualize large-scale neural dynamics in whole mammalian brains at…”
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2
A genetically encoded near-infrared fluorescent calcium ion indicator
Published in Nature methods (01-02-2019)“…We report an intensiometric, near-infrared fluorescent, genetically encoded calcium ion (Ca 2+ ) indicator (GECI) with excitation and emission maxima at 678…”
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Rapid volumetric optoacoustic imaging of neural dynamics across the mouse brain
Published in Nature biomedical engineering (01-05-2019)“…Efforts to scale neuroimaging towards the direct visualization of mammalian brain-wide neuronal activity have faced major challenges. Although high-resolution…”
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4
Detection of Shortwave-Infrared Cerenkov Luminescence from Medical Isotopes
Published in Journal of Nuclear Medicine (01-01-2023)“…Medical radioisotopes produce Cerenkov luminescence (CL) from charged subatomic particles (β ) traveling faster than light in dielectric media (e.g., tissue)…”
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High‐Speed Large‐Field Multifocal Illumination Fluorescence Microscopy
Published in Laser & photonics reviews (01-02-2020)“…Scanning optical microscopy techniques are commonly restricted to a sub‐millimeter field‐of‐view (FOV) or otherwise employ slow mechanical translation,…”
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6
Membrane-derived particles shed by PSMA-positive cells function as pro-angiogenic stimuli in tumors
Published in Journal of controlled release (01-12-2023)“…Cell membrane-derived particles (Mp) are rounded membrane-enclosed particles that are shed from tumor cells. Mp are formed from tumor membranes and are capable…”
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A review of recent and emerging approaches for the clinical application of Cerenkov luminescence imaging
Published in Frontiers in physics (28-07-2021)“…Cerenkov luminescence (CL) is a blue-weighted emission of light produced by a vast array of clinically approved radioisotopes and LINAC accelerators. When β…”
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High-throughput screening of caterpillars as a platform to study host–microbe interactions and enteric immunity
Published in Nature communications (24-11-2022)“…Mammalian models of human disease are expensive and subject to ethical restrictions. Here, we present an independent platform for high-throughput screening,…”
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Monitoring of Stimulus Evoked Murine Somatosensory Cortex Hemodynamic Activity With Volumetric Multi-Spectral Optoacoustic Tomography
Published in Frontiers in neuroscience (03-06-2020)“…Sensory stimulation is an attractive paradigm for studying brain activity using various optical-, ultrasound- and MRI-based functional neuroimaging methods…”
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10
Uniform light delivery in volumetric optoacoustic tomography
Published in Journal of biophotonics (01-06-2019)“…Accurate image reconstruction in volumetric optoacoustic tomography implies the efficient generation and collection of ultrasound signals around the imaged…”
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Rapid volumetric optoacoustic imaging of neural dynamics across the mouse brain
Published in Nature biomedical engineering (01-05-2019)Get full text
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Isolated Murine Brain Model for Large-Scale Optoacoustic Calcium Imaging
Published in Frontiers in neuroscience (24-04-2019)“…Real-time visualization of large-scale neural dynamics in whole mammalian brains is hindered with existing neuroimaging methods having limited capacity when it…”
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13
Publisher Correction: Rapid volumetric optoacoustic imaging of neural dynamics across the mouse brain
Published in Nature biomedical engineering (01-11-2020)“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Ambient Light Resistant Shortwave Infrared Fluorescence Imaging for Preclinical Tumor Delineation via the pH Low-Insertion Peptide Conjugated to Indocyanine Green
Published in Journal of Nuclear Medicine (01-10-2023)“…Shortwave infrared (900-1,700 nm) fluorescence imaging (SWIRFI) has shown significant advantages over visible (400-650 nm) and near-infrared (700-900 nm)…”
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Prospective testing of clinical Cerenkov luminescence imaging against standard-of-care nuclear imaging for tumour location
Published in Nature biomedical engineering (01-05-2022)“…In oncology, the feasibility of Cerenkov luminescence imaging (CLI) has been assessed by imaging superficial lymph nodes in a few patients undergoing…”
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High-throughput Screening of Caterpillars as Alternative Platform for Modeling of Gut Inflammation
Published in Developmental and comparative immunology (01-11-2023)Get full text
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Neuroimaging: High‐Speed Large‐Field Multifocal Illumination Fluorescence Microscopy (Laser Photonics Rev. 14(2)/2020)
Published in Laser & photonics reviews (01-02-2020)“…In article number 1900070, Daniel Razansky and co‐workers report on a novel optical microscopy concept termed large‐field multifocal illumination (LMI)…”
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A pan-cancer dye for solid-tumour screening, resection and wound monitoring via short-wave and near-infrared fluorescence imaging
Published in Nature biomedical engineering (01-09-2024)“…The efficacy of fluorescence-guided surgery in facilitating the real-time delineation of tumours depends on the optical contrast of tumour tissue over healthy…”
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Photophysical and biological assessment of coumarin-6 loaded polymeric nanoparticles as a cancer imaging agent
Published in Sensors & diagnostics (14-09-2023)“…Polymeric nanoparticles can prove beneficial in oncology as they sidestep limitations associated with traditional small-molecule pharmaceuticals. With respect…”
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