Search Results - "Mburu, Yvonne K"

MAIT cells, surveyors of a new class of antigen: development and functions by Le Bourhis, Lionel, Mburu, Yvonne K, Lantz, Olivier

“…Highlights ► MAIT cells recognize riboflavin derivatives originating from bacteria. ► Selection by hematopoietic thymic cells induce MAIT cell-specific…”
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Insufficient yet improving involvement of the global south in top sustainability science publications by Dangles, Olivier, Struelens, Quentin, Ba, Mame-Penda, Bonzi-Coulibaly, Yvonne, Charvis, Philippe, Emmanuel, Evens, González Almario, Carolina, Hanich, Lahoucine, Koita, Ousmane, León-Velarde, Fabiola, Mburu, Yvonne K, Ntoumi, Francine, Restrepo, Silvia, Vidal, Laurent

“…The creation of global research partnerships is critical to produce shared knowledge for the implementation of the UN 2030 Agenda for Sustainable Development…”
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High-throughput screening for TLR3-IFN regulatory factor 3 signaling pathway modulators identifies several antipsychotic drugs as TLR inhibitors by Zhu, Jianzhong, Smith, Kevin, Hsieh, Paishiun N, Mburu, Yvonne K, Chattopadhyay, Saurabh, Sen, Ganes C, Sarkar, Saumendra N

“…TLR3 is one of the major innate immune sensors of dsRNA. The signal transduction pathway activated by TLR3, upon binding to dsRNA, leads to the activation of…”
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Mucosal-associated invariant T cell-rich congenic mouse strain allows functional evaluation by Cui, Yue, Franciszkiewicz, Katarzyna, Mburu, Yvonne K, Mondot, Stanislas, Le Bourhis, Lionel, Premel, Virginie, Martin, Emmanuel, Kachaner, Alexandra, Duban, Livine, Ingersoll, Molly A, Rabot, Sylvie, Jaubert, Jean, De Villartay, Jean-Pierre, Soudais, Claire, Lantz, Olivier

“…Mucosal-associated invariant T cells (MAITs) have potent antimicrobial activity and are abundant in humans (5%-10% in blood). Despite strong evolutionary…”
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Chemokine Receptor 7 (CCR7) Gene Expression Is Regulated by NF-κB and Activator Protein 1 (AP1) in Metastatic Squamous Cell Carcinoma of Head and Neck (SCCHN) by Mburu, Yvonne K., Egloff, Ann Marie, Walker, William H., Wang, Lin, Seethala, Raja R., van Waes, Carter, Ferris, Robert L.

“…The chemokine receptor CCR7 is a seven-transmembrane domain G-protein-coupled receptor that facilitates leukocyte migration to regional lymph nodes. Aberrant…”
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Human Beta-Defensin 3 Induces Maturation of Human Langerhans Cell–Like Dendritic Cells: An Antimicrobial Peptide that Functions as an Endogenous Adjuvant by Ferris, Laura K., Mburu, Yvonne K., Mathers, Alicia R., Fluharty, Eric R., Larregina, Adriana T., Ferris, Robert L., Falo, Louis D.

“…Human beta-defensins (hBDs) are antimicrobial peptides that have an important role in innate immune responses at epithelial barriers such as the skin. However,…”
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Human β-defensin 3 promotes NF-KB-mediated CCR7 expression and anti-apoptotic signals in squamous cell carcinoma of the head and neck by MBURU, Yvonne K, ABE, Koji, FERRIS, Laura K, SARKAR, Saumendra N, FERRIS, Robert L

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Human β-defensin 3 promotes NF-κB-mediated CCR7 expression and anti-apoptotic signals in squamous cell carcinoma of the head and neck by Mburu, Yvonne K, Abe, Koji, Ferris, Laura K, Sarkar, Saumendra N, Ferris, Robert L

“…The microenvironment of aerodigestive cancers contains tumor-promoting inflammatory signals often involved in innate immunity. The epithelial malignancy,…”
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Defective NF-κB Signaling in Metastatic Head and Neck Cancer Cells Leads to Enhanced Apoptosis by Double-Stranded RNA by UMEMURA, Naoki, JIANZHONG ZHU, MBURU, Yvonne K, FORERO, Adriana, HSIEH, Paishiun N, MUTHUSWAMY, Ravikumar, KALINSKI, Pawel, FERRIS, Robert L, SARKAR, Saumendra N

“…Ligands to several Toll-like receptors (TLR), which mediate innate immune responses and chronic inflammation have been used as adjuvants to immunotherapy to…”
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Making clinical trials a public norm for health decisions in sub-Saharan Africa by Agnandji, Selidji T., Loembe, Marguerite Massinga, Mbouna, Armel V., Mbadinga, Fallowne, Essone, Paulin N., Mombo-Ngoma, Ghyslain, Leke, Rose, Mburu, Yvonne K., Muyembe-Tamfum, Jean-Jacques, Okwo-Bele, Jean-Marie, Sow, Samba, Wiysonge, Charles Shey, Zumla, Alimuddin, Adegnika, Ayola A., Ramharter, Michael, Kremsner, Peter G., Matsiegui, Pierre-Blaise, Boum, Yap, Ntoumi, Francine

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CCR7 mediates inflammation-associated tumor progression by Mburu, Yvonne K, Wang, Jun, Wood, Michelle A, Walker, William H, Ferris, Robert L

“…Chemokine receptor 7 (CCR7) mediates leukocyte adhesion and chemotaxis from peripheral sites of inflammation through lymphatic channels to secondary lymphoid…”
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PS3-14 A high throughput screen of TLR3-IRF3 signaling pathway modulators identifies several anti-pyschotic drugs as TLR modulators by Zhu, Jianzhong, Smith, Kevin, Hsieh, Paishiun N., Mburu, Yvonne K., Chattopadhyay, Saurabh, Sen, Ganes C., Sarkar, Saumendra N.

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Mucosal-associated invariant T cell-rich congenie mouse strain allows functional evaluation by Cui, Yue, Franciszkiewicz, Katarzyna, Mburu, Yvonne K, Mondot, Stanislas, Bourhis, Lionel Le, Premel, Virginie, Martin, Emmanuel, Kachaner, Alexandra, Duban, Livine, Ingersoll, Molly A, Rabot, Sylvie, Jaubert, Jean, De Villartay, Jean- Pierre, Soudais, Claire, Lantz, Olivier

“…Mucosal-associated invariant T cells (MAITs) have potent antimicrobial activity and are abundant in humans (5%-10% in blood). Despite strong evolutionary…”
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Defective NF-κB signaling in metastatic head and neck cancer cells leads to enhanced apoptosis by dsRNA by Umemura, Naoki, Zhu, Jianzhong, Mburu, Yvonne K., Forero, Adriana, Hsieh, Paishiun N., Muthuswamy, Ravikumar, Kalinski, Pawel, Ferris, Robert L., Sarkar, Saumendra N.

“…Ligands to several Toll-like receptors (TLR) which mediate innate immune responses and chronic inflammation have been used as adjuvants to immunotherapy to…”
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A high throughput screening for TLR3-IRF3 signaling pathway modulators identifies several antipsychotic drugs as TLR inhibitors1 by Zhu, Jianzhong, Smith, Kevin, Hsieh, Paishiun N., Mburu, Yvonne K., Chattopadhyay, Saurabh, Sen, Ganes C., Sarkar, Saumendra N.

“…Toll-like Receptor 3 (TLR3) is one of the major innate immune sensors of double stranded RNA (dsRNA). The signal transduction pathway activated by TLR3, upon…”
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PS3-14 A high throughput screen of TLR3-IRF3 signaling pathway modulators identifies several anti-pyschotic drugs as TLR modulators1This work was supported in part by Scientist Development Grant from American Heart Association (SNS), CA06220 from National Cancer Institute (GCS), AI082673 from National Institute of Allergy and Infectious Diseases (SNS), and University of Pittsburgh Cancer Institute Start up funds (SNS).1 by Zhu, Jianzhong, Smith, Kevin, Hsieh, Paishiun N., Mburu, Yvonne K., Chattopadhyay, Saurabh, Sen, Ganes C., Sarkar, Saumendra N.

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Inflammatory mechanisms of chemokine receptor 7 expression in metastatic squamous cell carcinoma of the head and neck (SCCHN) by Mburu, Yvonne K

“…The microenvironment of aerodigestive cancers contains tumor promoting inflammatory signals often involved in innate immunity. SCCHN is an epithelial…”
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Inflammatory mechanisms of chemokine receptor 7 expression in metastatic squamous cell carcinoma of the head and neck (SCCHN) by Mburu, Yvonne K

“…The microenvironment of aerodigestive cancers contains tumor promoting inflammatory signals often involved in innate immunity. SCCHN is an epithelial…”
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