Search Results - "Mbofung, R"

CpG-based immunotherapy impairs antitumor activity of BRAF inhibitors in a B-cell-dependent manner by Huang, L, Wang, Z, Liu, C, Xu, C, Mbofung, R M, McKenzie, J A, Khong, H, Hwu, P, Peng, W

“…Combining immunotherapy with targeted therapy has increasingly become an appealing therapeutic paradigm for cancer treatment due to its great potential for…”
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Genetic ablation of adhesion ligands effectively averts rejection of allogeneic immune cells by Hammer, Q., Perica, K., Mbofung, R. M., van Ooijen, Hanna, Goodridge, J. P., Valamehr, B., Önfelt, Björn, Sadelain, M., Malmberg, K. J.

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A novel synthetic stealth receptor that redirects host immune cell alloreactivity and potentiates functional persistence of adoptively transferred off-the-shelf cell-based cancer therapy by Williams, AM, Hayama, K, Pan, YJ, Groff, B, Mbofung, R, Fong, L, Brookhouser, N, Mandefro, B, Abujarour, R, Lee, T, Hammer, Q, Malmberg, KJ, Mamonkin, M, Bjordahl, R, Goodridge, J, Valamehr, B

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Genetic ablation of adhesion ligands mitigates rejection of allogeneic cellular immunotherapies by Hammer, Quirin, Perica, Karlo, Mbofung, Rina M, van Ooijen, Hanna, Martin, Karen E, Momayyezi, Pouria, Varady, Erika, Pan, Yijia, Jelcic, Mark, Groff, Brian, Abujarour, Ramzey, Krokeide, Silje Z, Lee, Tom, Williams, Alan, Goodridge, Jode P, Valamehr, Bahram, Önfelt, Björn, Sadelain, Michel, Malmberg, Karl-Johan

“…Allogeneic cellular immunotherapies hold promise for broad clinical implementation but face limitations due to potential rejection of donor cells by the host…”
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Combined Genetic Ablation of CD54 and CD58 in CAR Engineered Cytotoxic Lymphocytes Effectively Averts Allogeneic Immune Cell Rejection by Hammer, Quirin, Perica, Karlo, Mbofung, Rina M, van Ooijen, Hanna, Varady, Erika, Jelcic, Mark, Pan, Yijia, Momayyezi, Pouria, Groff, Brian, Abujarour, Ramzey, Krokeide, Silje Zandstra, Lee, Tom, Williams, Alan M, Goodridge, Jode P, Valamehr, Bahram, Onfelt, Bjorn, Sadelain, Michel, Malmberg, Karl-Johan

“…Allogeneic cell therapies hold promise to be cost effective with scaled manufacturing for multi-dosing and on-demand off-the-shelf availability. A critical…”
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A Novel Stealth Strategy That Activates Adoptively Transferred Allogeneic Immune Cells and Avoids Rejection for Off-the-Shelf Cell-Based Cancer Therapy by Williams, Alan M, Hayama, Ken, Pan, Yijia, Groff, Brian, Mbofung, Rina M, Fong, Lauren, Brookhouser, Nicholas, Mandefro, Berhan, Abujarour, Ramzey, Lee, Tom, Hammer, Quirin, Malmberg, Karl-Johan, Mamonkin, Maksim, Bjordahl, Ryan, Goodridge, Jode P, Valamehr, Bahram

“…Chimeric antigen receptor (CAR) T-cell therapies have revolutionized the treatment of hematologic malignancies, however, logistical complexities associated…”
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Off-the-Shelf, iPSC-Derived CAR-NK Cells Multiplexed-Engineered for the Avoidance of Allogeneic Host Immune Cell Rejection by Mbofung, Rina M, Williams, Alan M, Hayama, Ken, Pan, Yijia, Groff, Brian, Dailey, Thomas, Reyes, Sonia, Mahmood, Sajid, Mathavan, Ketan, Bonello, Greg, Hammer, Quirin, Malmberg, Karl-Johan, Lee, Tom, Bjordahl, Ryan, Goodridge, Jode P, Valamehr, Bahram

“…Allogeneic off-the-shelf cell therapies offer distinct advantages over conventional autologous cell therapies in terms of scaled manufacturing, on-demand…”
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iPSC-Derived CD38-Null NK Cells in Combination with CD38-Targeted Antibody Represent a Novel Therapeutic Strategy to Avoid Host Immune Cell Rejection for Off-the-Shelf Cell-Based Cancer Immunotherapy by Williams, AM, Mbofung, RM, Karimi, M, Hayama, K, Pan, YJ, Groff, B, Dailey, T, Meza, M, Mahmood, S, Mathavan, K, Bonello, G, Lee, T, Hammer, Q, Malmberg, KJ, Szabo, PM, Wong, L, Cooley, S, Bjordahl, R, Goodridge, J, Valamehr, B

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