Search Results - "Mazzone, S B"

Transneuronal tracing of airways-related sensory circuitry using herpes simplex virus 1, strain H129 by McGovern, A.E, Davis-Poynter, N, Farrell, M.J, Mazzone, S.B

“…Abstract Sensory input from the airways to suprapontine brain regions contributes to respiratory sensations and the regulation of respiratory function…”
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Cough sensors. V. Pharmacological modulation of cough sensors by Mazzone, S B, Undem, B J

“…Several airway afferent nerve subtypes have been implicated in coughing. These include bronchopulmonary C-fibers, rapidly adapting airway mechanoreceptors and…”
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Respiratory action of capsaicin microinjected into the nucleus of the solitary tract: involvement of vanilloid and tachykinin receptors by Mazzone, Stuart B, Geraghty, Dominic P

“…The respiratory response to microinjection of capsaicin into the commissural nucleus of the solitary tract (cNTS) of urethane‐anaesthetized rats was…”
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Respiratory actions of tachykinins in the nucleus of the solitary tract: characterization of receptors using selective agonists and antagonists by Mazzone, Stuart B, Geraghty, Dominic P

“…The respiratory response to microinjection of tachykinins and analogues into the commissural nucleus of the solitary tract (cNTS) of urethane‐anaesthetized…”
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Sensations and regional brain responses evoked by tussive stimulation of the airways by Farrell, M.J, Mazzone, S.B

“…Highlights • Tussive stimulation evokes a sensation of urge-to-cough that can occur independently of the motor cough response. • The urge-to-cough is…”
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Respiratory actions of tachykinins in the nucleus of the solitary tract: effect of neonatal capsaicin pretreatment by Mazzone, Stuart B, Geraghty, Dominic P

“…The respiratory response to microinjection of capsaicin and tachykinin receptor agonists into the commissural nucleus of the solitary tract (cNTS) was…”
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Representation of Capsaicin-evoked Urge-to-Cough in the Human Brain Using Functional Magnetic Resonance Imaging by Mazzone, Stuart B, McLennan, Lisa, McGovern, Alice E, Egan, Gary F, Farrell, Michael J

“…Coughing in humans is typically preceded by a desire (or urge) to cough. The neural circuitry involved in sensing airway irritation and generating the…”
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Altered respiratory response to substance P and reduced NK1 receptor binding in the nucleus of the solitary tract of aged rats by Mazzone, Stuart B, Geraghty, Dominic P

“…The respiratory response to microinjection of substance P (SP) into the commissural nucleus of the solitary tract (cNTS) and binding of [ 125 I ]–Bolton–Hunter…”
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Hypoxia attenuates the respiratory response to injection of substance P into the nucleus of the solitary tract of the rat by Mazzone, Stuart B, Hinrichsen, Colin F, Geraghty, Dominic P

“…Prolonged or repetitive bouts of hypoxia may desensitize the brain stem respiratory centres leading to reduced stimulation of ventilation. We investigated the…”
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Autoradiographic localisation of substance P (NK1) receptors in human primary visual cortex by Kus, Laura, Mazzone, Stuart B, Paxinos, George, Geraghty, Dominic P

“…This study utilised autoradiography to examine [ 125 I ]-Bolton Hunter substance P (BHSP) binding in postmortem human visual cortex. In the primary visual…”
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Multiple mechanisms of reflex bronchospasm in guinea pigs by Canning, Brendan J, Reynolds, Sandra M, Mazzone, Stuart B

“…The Johns Hopkins Asthma and Allergy Center, Baltimore, Maryland 21224 The mechanisms of histamine- and bradykinin-induced reflex bronchospasm were determined…”
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A worldwide survey of chronic cough: a manifestation of enhanced somatosensory response by MORICE, Alyn H, JAKES, Adam D, PAVORD, Ian D, VAN DEN BERG, Jan, SONG, Woo-Jung, MILLQVIST, Eva, FARRELL, Michael J, MAZZONE, Stuart B, DICPINIGAITIS, Peter, FARUQI, Shoaib, BIRRING, Surinder S, MCGARVEY, Lorcan, CANNING, Brendan, SMITH, Jaclyn A, PARKER, Sean M, KIAN FAN CHUNG, KEFANG LAI

“…Reports from individual centres suggest a preponderance of females with chronic cough. Females also have heightened cough reflex sensitivity. Here we have…”
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Tachykinin receptor (NK 1, NK 2, NK 3) binding sites in the rat caudal brainstem following neonatal capsaicin administration by Geraghty, Dominic P., Mazzone, Stuart B.

“…Binding of [ 125I]-Bolton–Hunter substance P ([ 125I]-BHSP), [ 125I]-neurokinin A and [ 3H]-senktide to tachykinin NK 1, NK 2 and NK 3 receptors, respectively,…”
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Pharmacology of Bradykinin-Evoked Coughing in Guinea Pigs by Hewitt, Matthew M, Adams, Jr, Gregory, Mazzone, Stuart B, Mori, Nanako, Yu, Li, Canning, Brendan J

“…Bradykinin has been implicated as a mediator of the acute pathophysiological and inflammatory consequences of respiratory tract infections and in exacerbations…”
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Substance P receptors in brain stem respiratory centers of the rat: regulation of NK1 receptors by hypoxia by Mazzone, S B, Hinrichsen, C F, Geraghty, D P

“…Substance P (SP) is a key neurotransmitter involved in the brain stem integration of carotid body chemoreceptor reflexes. In this study, the characteristics…”
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Characterization And Regulation Of Tachykinin Receptors In The Nucleus Tractus Solitarius by Mazzone, Stuart B, Geraghty, Dominic P

“…SUMMARY 1. The characteristics, localization and regulation of tachykinin receptors in the rat nucleus tractus solitarius (NTS) involved in respiratory control…”
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Neural correlates coding stimulus level and perception of capsaicin-evoked urge-to-cough in humans by Farrell, Michael J., Cole, Leonie J., Chiapoco, David, Egan, Gary F., Mazzone, Stuart B.

“…The perception of airways irritation is represented in a distributed brain network. However, the functional roles of sub-regions of this network are yet to be…”
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Synergistic interactions between airway afferent nerve subtypes regulating the cough reflex in guinea-pigs by Mazzone, Stuart B., Mori, Nanako, Canning, Brendan J.

“…Cough initiated from the trachea and larynx in anaesthetized guinea-pigs is mediated by capsaicin-insensitive, mechanically sensitive vagal afferent neurones…”
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Reflex regulation of breathing by the paratrigeminal nucleus via multiple bulbar circuits by Driessen, Alexandria K., Farrell, Michael J., Dutschmann, Mathias, Stanic, Davor, McGovern, Alice E., Mazzone, Stuart B.

“…Sensory neurons of the jugular vagal ganglia innervate the respiratory tract and project to the poorly studied medullary paratrigeminal nucleus. In the present…”
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Identification of the tracheal and laryngeal afferent neurones mediating cough in anaesthetized guinea-pigs by Canning, Brendan J., Mazzone, Stuart B., Meeker, Sonya N., Mori, Nanako, Reynolds, Sandra M., Undem, Bradley J.

“…We have identified the tracheal and laryngeal afferent nerves regulating cough in anaesthetized guinea-pigs. Cough was evoked by electrical or mechanical…”
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