Search Results - "Mazzi, Valeria"
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Immune and Inflammatory Cells in Thyroid Cancer Microenvironment
Published in International journal of molecular sciences (07-09-2019)“…A hallmark of cancer is the ability of tumor cells to avoid immune destruction. Activated immune cells in tumor microenvironment (TME) secrete proinflammatory…”
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Precision Medicine in Autoimmune Thyroiditis and Hypothyroidism
Published in Frontiers in pharmacology (17-11-2021)“…Autoimmune thyroid diseases (AITD) are T-cell-mediated organ specific autoimmune disorders, deriving from an altered response of the immune system that leads…”
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Antineoplastic Effect of ALK Inhibitor Crizotinib in Primary Human Anaplastic Thyroid Cancer Cells with STRN-ALK Fusion In Vitro
Published in International journal of molecular sciences (19-06-2024)“…Anaplastic thyroid cancer (ATC) is one of the deadliest human cancers and represents <2% of thyroid carcinomas. A therapeutic target for ATC is represented by…”
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Combination Strategies Involving Immune Checkpoint Inhibitors and Tyrosine Kinase or BRAF Inhibitors in Aggressive Thyroid Cancer
Published in International journal of molecular sciences (20-05-2022)“…Thyroid cancer is the most common (~90%) type of endocrine-system tumor, accounting for 70% of the deaths from endocrine cancers. In the last years, the…”
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Precision Medicine in Graves’ Disease and Ophthalmopathy
Published in Frontiers in pharmacology (28-10-2021)“…Graves’ disease (GD) is a condition caused by an autoimmune process involving the thyroid gland, whose main outcome is hyperthyroidism. TSAb start the…”
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Molecular features of aggressive thyroid cancer
Published in Frontiers in oncology (20-12-2022)“…Poorly differentiated thyroid cancer (PDTC) and anaplastic thyroid cancer (ATC) have a worse prognosis with respect to well differentiated TC, and the loss of…”
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Antineoplastic Activity of Pazopanib in Anaplastic Thyroid Cancer in Primary Culture
Published in International journal of molecular sciences (25-01-2023)“…Anaplastic thyroid cancer (ATC) is a rare and rapidly fatal human cancer. Its usual treatment includes the combination of surgery, external hyperfractionated…”
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New therapies for dedifferentiated papillary thyroid cancer
Published in International Journal of Molecular Sciences (17-03-2015)“…The number of thyroid cancers is increasing. Standard treatment usually includes primary surgery, thyroid-stimulating hormone suppressive therapy, and ablation…”
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Hypothyroidism and metabolic cardiovascular disease
Published in Frontiers in endocrinology (Lausanne) (03-06-2024)“…Cardiovascular disease (CVD) remains the leading cause of death worldwide, representing a major health issue of social and economic relevance. Both…”
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Simultaneous Occurrence of Medullary Thyroid Carcinoma and Papillary Thyroid Carcinoma: A Case Series with Literature Review
Published in Current oncology (Toronto) (30-11-2023)“…Papillary thyroid carcinoma (PTC) is the most common type of differentiated TC, while medullary TC (MTC) accounts for 4%. The concomitant presence of PTC and…”
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Immunomodulation of CXCL10 Secretion by Hepatitis C Virus: Could CXCL10 Be a Prognostic Marker of Chronic Hepatitis C?
Published in Journal of immunology research (2019)“…Chemokine (C-X-C motif) ligand (CXCL)10 and other CXCR3 chemokines are involved in the pathogenesis of acute and “chronic hepatitis C virus (HCV) infection”…”
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Graves’ Disease Following SARS-CoV-2 Vaccination: A Systematic Review
Published in Vaccines (Basel) (01-09-2022)“…(1) Background: Autoimmune diseases, including autoimmune endocrine diseases (AIED), are thought to develop following environmental exposure in patients with…”
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Chemokines in hyperthyroidism
Published in Journal of clinical & translational endocrinology (01-06-2019)“…AbstractThe term “hyperthyroidism” indicates a condition due to an exaggerate production of thyroid hormone; the most frequent cause is Graves’ disease (GD)…”
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Liquid L-T4 therapy in hypothyroid patients with gastric diseases, an observational study
Published in Frontiers in endocrinology (Lausanne) (04-07-2024)“…This is an observational and retrospective study, in which we have analyzed data from patients affected by gastric diseases (p) who have been treated with…”
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The risk of post-thrombotic syndrome in patients with proximal deep vein thrombosis treated with the direct oral anticoagulants
Published in Internal and emergency medicine (01-04-2020)“…The novel direct oral anticoagulants (DOAC) have been shown to be at least as effective as and safer than conventional anticoagulants for the initial and…”
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Lactose intolerance and levothyroxine malabsorption: a review of the literature and report of a series of patients treated with liquid L-T4 without lactose
Published in Frontiers in endocrinology (Lausanne) (11-04-2024)“…In hypothyroid patients needing large doses of levothyroxine (L-T4) (>1.7-2 μg/kg/day) to reach euthyroidism, lactose intolerance (LI) needs to be excluded,…”
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The Clinical Impact of the Pulmonary Embolism Severity Index on the Length of Hospital Stay of Patients with Pulmonary Embolism: A Randomized Controlled Trial
Published in Diagnostics (Basel) (01-04-2024)“…The Pulmonary Embolism Severity Index (PESI) is an extensively validated prognostic score, but impact analyses of the PESI on management strategies, outcomes…”
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Circulating CXCL11 and CXCL10 are increased in hepatitis C-associated cryoglobulinemia in the presence of autoimmune thyroiditis
Published in Modern rheumatology (01-09-2012)“…Objective No data are available about circulating levels of the CXCL11 chemokine in hepatitis C virus (HCV)-associated mixed cryoglobulinemia (MC) patients…”
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New targeted therapies for anaplastic thyroid cancer
Published in Anti-cancer agents in medicinal chemistry (01-01-2012)“…Anaplastic thyroid cancer (ATC) is often incurable because it doesn't respond to radioiodine, radiotherapy or chemotherapy, and new therapeutic approaches are…”
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Personalization of Targeted Therapy in Advanced Thyroid Cancer
Published in Current genomics (01-06-2014)“…Although generally the prognosis of differentiated thyroid carcinoma (DTC) is good, approximately 5% of people are likely to develop metastases which fail to…”
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