Search Results - "Mazzarella, Brian C"
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Urinary comprehensive genomic profiling predicts urothelial carcinoma recurrence and identifies responders to intravesical therapy
Published in Molecular oncology (01-02-2024)“…Intravesical therapy (IVT) is the standard of care to decrease risk of recurrence and progression for high‐grade nonmuscle‐invasive bladder cancer. However,…”
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Development and multicenter case-control validation of urinary comprehensive genomic profiling for urothelial carcinoma diagnosis, surveillance, and risk prediction
Published in Clinical cancer research (15-09-2023)“…Urinary comprehensive genomic profiling (uCGP) uses next-generation sequencing to identify mutations associated with urothelial carcinoma (UC) and has the…”
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Decreasing need for artificial urinary sphincter revision surgery by precise cuff sizing in men with spongiosal atrophy
Published in The Journal of urology (01-09-2014)“…Many patients with persistent incontinence after an artificial urinary sphincter procedure gain improved continence after cuff downsizing. In 2010 a new,…”
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Minimal Residual Disease Detection with Urine-derived DNA Is Prognostic for Recurrence-free Survival in Bacillus Calmette-Guérin–unresponsive Non–muscle-invasive Bladder Cancer Treated with Nadofaragene Firadenovec
Published in European urology oncology (14-10-2024)“…In patients with bacillus Calmette-Guérin–unresponsive non–muscle-invasive bladder cancer, urine DNA profiling identifies those with the greatest likelihood of…”
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Urinary Comprehensive Genomic Profiling Correlates Urothelial Carcinoma Mutations with Clinical Risk and Efficacy of Intervention
Published in Journal of clinical medicine (30-09-2022)“…The clinical standard of care for urothelial carcinoma (UC) relies on invasive procedures with suboptimal performance. To enhance UC treatment, we developed a…”
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Clinical utility of urinary comprehensive genomic profiling in diagnosing metachronous upper tract urothelial carcinoma: a case report
Published in Frontiers in Urology (09-08-2023)“…Introduction and aim of study Metachronous upper tract urothelial carcinoma (UTUC) is a rare yet aggressive malignancy that is often multifocal and invasive at…”
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Urinary minimal residual disease detection predicts recurrence in BCG-unresponsive NIMBC and quantifies molecular response to nadofaragene firadenovec
Published in Journal of clinical oncology (01-02-2024)“…635 Background: Urinary minimal residual disease (uMRD) profiling uses next-generation sequencing to identify mutations associated with urothelial carcinoma…”
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Comprehensive genomic profiling of urine DNA for urothelial carcinoma detection and risk prediction
Published in Journal of clinical oncology (20-02-2022)“…Abstract only 450 Background: Clinical diagnosis and risk stratification of patients with urothelial carcinoma (UC) remains a challenge, with high rates of…”
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DETECTION, RISK STRATIFICATION, AND THERAPUETIC SELECTION FOR UPPER TRACT UROTHELIAL CARCINOMA WITH URINE-BASED COMPREHENSIVE GENOMIC PROFILING
Published in Urologic oncology (01-03-2024)“…Upper tract urothelial carcinoma (UTUC) is a rare and aggressive malignancy that is difficult to diagnose and stage. A urine test capable of detecting UTUC…”
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