Search Results - "Mazyed, Eman"
-
1
Fabrication of Transgelosomes for Enhancing the Ocular Delivery of Acetazolamide: Statistical Optimization, In Vitro Characterization, and In Vivo Study
Published in Pharmaceutics (20-05-2020)“…Acetazolamide (ACZ) is a potent carbonic anhydrase inhibitor that is used for the treatment of glaucoma. Its oral administration causes various undesirable…”
Get full text
Journal Article -
2
Glyceroniosomes for enhanced intestinal absorption of hydrochlorothiazide and lisinopril in their fixed dose combination
Published in Scientific reports (18-10-2024)“…The objective was to investigate the effect of co-administration of hydrochlorothiazide and lisinopril as fixed dose combination on their intestinal…”
Get full text
Journal Article -
3
Development of Provesicular Nanodelivery System of Curcumin as a Safe and Effective Antiviral Agent: Statistical Optimization, In Vitro Characterization, and Antiviral Effectiveness
Published in Molecules (Basel, Switzerland) (01-12-2020)“…Curcumin is a natural compound that has many medical applications. However, its low solubility and poor stability could impede its clinical applications. The…”
Get full text
Journal Article -
4
Formulation and optimization of folate-bovine serum albumin-coated ethoniosomes of pterostilbene as a targeted drug delivery system for lung cancer: In vitro and in vivo demonstrations
Published in Cancer nanotechnology (01-12-2023)“…This study aimed to overcome the poor solubility of pterostilbene (PTS) by developing promising reconstituted proethoniosomes (PENs). The reconstituted PENs…”
Get full text
Journal Article -
5
Formulation and Optimization of Nanospanlastics for Improving the Bioavailability of Green Tea Epigallocatechin Gallate
Published in Pharmaceuticals (Basel, Switzerland) (15-01-2021)“…The present study aimed to investigate the potential of nanospanlastics for boosting the bioavailability of epigallocatechin gallate (EGCG). EGCG has valuable…”
Get full text
Journal Article -
6
Formulation of Deformable Liponiosomal Hybrid of Repaglinide: In vitro Characterization and Evaluation of the Anti-Diabetic Effect
Published in International journal of nanomedicine (01-01-2023)“…The current study sought to create novel deformable liponiosomal hybrids (LNHs) as a viable RPG delivery system. Repaglinide (RPG) is an effective…”
Get full text
Journal Article -
7
Formulation of Sodium Valproate Nanospanlastics as a Promising Approach for Drug Repurposing in the Treatment of Androgenic Alopecia
Published in Pharmaceutics (11-09-2020)“…Sodium valproate (SV) is an antiepileptic drug that is widely used in the treatment of different seizure disorders. The topical SV has a hair regenerative…”
Get full text
Journal Article -
8
Novel spirooxindole based benzimidazole scaffold: In vitro, nanoformulation and in vivo studies on anticancer and antimetastatic activity of breast adenocarcinoma
Published in Bioorganic chemistry (01-12-2022)“…[Display omitted] •A novel spirooxindole based benzimidazole SP1 was designed and synthesized.•SP1 was assessed against cancer cell lines in vitro, in vivo,…”
Get full text
Journal Article -
9
Development of Cyclodextrin-Functionalized Transethoniosomes of 6-Gingerol: Statistical Optimization, In Vitro Characterization and Assessment of Cytotoxic and Anti-Inflammatory Effects
Published in Pharmaceutics (30-05-2022)“…The poor solubility and stability of 6-gingerol (6-G) could hamper its clinical applications. The aim of the current study was to develop a novel…”
Get full text
Journal Article -
10
-
11
Patient-friendly extemporaneous formulation of bisoprolol: application to stability and bioavailability studies
Published in Drug delivery and translational research (01-03-2023)“…Community and hospital pharmacists always face the challenge to prepare oral liquid extemporaneous formulations to fit the needs of a specific patient…”
Get full text
Journal Article -
12
Preparation of orodispersible tablets of bosentan using xylitol and menthol as dissolution enhancers
Published in Scientific reports (09-05-2024)“…Bosentan is a drug used to treat pulmonary hypertension via dual endothelial receptor antagonism. Bosentan has a restricted oral bioavailability, a problem…”
Get full text
Journal Article -
13
Formulation of Nanospanlastics as a Promising Approach for Improving the Topical Delivery of a Natural Leukotriene Inhibitor
Published in Drug design, development and therapy (30-09-2020)“…Purpose: The current study aimed to discuss the potential of nanospanlastics as a surfactant-based vesicular system for improving the topical delivery of…”
Get full text
Journal Article -
14
Formulation of Nanospanlastics as a Promising Approach for Improving the Topical Delivery of a Natural Leukotriene Inhibitor (3-Acetyl-11-Keto-β-Boswellic Acid): Statistical Optimization, in vitro Characterization, and ex vivo Permeation Study
Published in Drug design, development and therapy (01-01-2020)“…The current study aimed to discuss the potential of nanospanlastics as a surfactant-based vesicular system for improving the topical delivery of…”
Get full text
Journal Article -
15
Formulation and characterization of quercetin-loaded Prunus armeniaca gum nanoparticles with enhanced anti-bacterial effect
Published in Journal of drug delivery science and technology (01-04-2024)“…Owing to the dissemination of antibiotic resistance among Staphylococcus aureus bacteria, it is critical to find out new, safe, and effective alternatives…”
Get full text
Journal Article -
16
Bio-friendly oleic acid-based ufasomal topical gel of rosuvastatin for diabetic wound healing: In-vitro, ex-Vivo, and in-Vivo evaluation
Published in Journal of drug delivery science and technology (01-08-2024)“…This study aimed to develop bio-friendly and biodegradable oleic acid-based ufasomes coated with chitosan for topical delivery of rosuvastatin for diabetic…”
Get full text
Journal Article -
17
Co-processing of fluconazole with menthol for enhanced dissolution and anti-fungal activity: Preparation of orodispersable tablets
Published in Journal of drug delivery science and technology (01-10-2023)“…The objective was to enhance the dissolution rate and anti-fungal activity of fluconazole. Mixtures of fluconazole with menthol were subjected to ethanol aided…”
Get full text
Journal Article -
18