Search Results - "Mazurier, Frédéric"

Characterization of Biomarkers of Tumorigenic and Chemoresistant Cancer Stem Cells in Human Gastric Carcinoma by Nguyen, Phu Hung, Giraud, Julie, Chambonnier, Lucie, Dubus, Pierre, Wittkop, Linda, Belleannée, Geneviève, Collet, Denis, Soubeyran, Isabelle, Evrard, Serge, Rousseau, Benoit, Senant-Dugot, Nathalie, Mégraud, Francis, Mazurier, Frédéric, Varon, Christine

“…Gastric carcinomas are heterogeneous, and the current therapy remains essentially based on surgery with conventional chemotherapy and radiotherapy. This study…”
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A comparative study of the capacity of mesenchymal stromal cell lines to form spheroids by Deynoux, Margaux, Sunter, Nicola, Ducrocq, Elfi, Dakik, Hassan, Guibon, Roseline, Burlaud-Gaillard, Julien, Brisson, Lucie, Rouleux-Bonnin, Florence, le Nail, Louis-Romée, Hérault, Olivier, Domenech, Jorge, Roingeard, Philippe, Fromont, Gaëlle, Mazurier, Frédéric, Asakura, Atsushi

“…Mesenchymal stem cells (MSC)-spheroid models favor maintenance of stemness, ex vivo expansion and transplantation efficacy. Spheroids may also be considered as…”
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Signaling pathways activated by PACAP in MCF-7 breast cancer cells by Zibara, Kazem, Zeidan, Asad, Mallah, Khalil, Kassem, Nouhad, Awad, Ali, Mazurier, Frédéric, Badran, Bassam, El-Zein, Nabil

“…PACAP has opposing roles ranging from activation to inhibition of tumor growth and PACAP agonists/antagonists could be used in tumor therapy. In this study,…”
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Hypoxia Regulates Lymphoid Development of Human Hematopoietic Progenitors by Chabi, Sara, Uzan, Benjamin, Naguibneva, Irina, Rucci, Julien, Fahy, Lucine, Calvo, Julien, Arcangeli, Marie-Laure, Mazurier, Frédéric, Pflumio, Françoise, Haddad, Rima

“…Hypoxia plays a major role in the physiology of hematopoietic and immune niches. Important clues from works in mouse have paved the way to investigate the role…”
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VAS3947 Induces UPR-Mediated Apoptosis through Cysteine Thiol Alkylation in AML Cell Lines by El Dor, Maya, Dakik, Hassan, Polomski, Marion, Haudebourg, Eloi, Brachet, Marie, Gouilleux, Fabrice, Prié, Gildas, Zibara, Kazem, Mazurier, Frédéric

“…Nicotinamide adenine dinucleotide phosphate (NADPH) oxidases (NOX) involvement has been established in the oncogenic cell signaling of acute myeloid leukemia…”
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Rapid myeloerythroid repopulation after intrafemoral transplantation of NOD-SCID mice reveals a new class of human stem cells by Dick, John E, Mazurier, Frédéric, Doedens, Monica, Gan, Olga I

“…A major problem hampering effective stem cell-based therapies is the absence of a clear understanding of the human hematopoietic stem cell (HSC) pool…”
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Protective Effects of Catalase Overexpression on UVB-induced Apoptosis in Normal Human Keratinocytes by Rezvani, Hamid Reza, Mazurier, Frédéric, Cario-André, Muriel, Pain, Catherine, Ged, Cécile, Taïeb, Alain, de Verneuil, Hubert

“…UV-induced apoptosis in keratinocytes is a highly complex process in which various molecular pathways are involved. These include the extrinsic pathway via…”
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Characterization of NADPH Oxidase Expression and Activity in Acute Myeloid Leukemia Cell Lines: A Correlation with the Differentiation Status by Dakik, Hassan, El Dor, Maya, Leclerc, Joan, Kouzi, Farah, Nehme, Ali, Deynoux, Margaux, Debeissat, Christelle, Khamis, Georges, Ducrocq, Elfi, Ibrik, Aida, Stasia, Marie-José, Raad, Houssam, Rezvani, Hamid Reza, Gouilleux, Fabrice, Zibara, Kazem, Herault, Olivier, Mazurier, Frédéric

“…In acute myeloid leukemia (AML), a low level of reactive oxygen species (ROS) is associated with leukemic stem cell (LSC) quiescence, whereas a high level…”
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Clinical-scale cultures of cord blood CD34(+) cells to amplify committed progenitors and maintain stem cell activity by Ivanovic, Zoran, Duchez, Pascale, Chevaleyre, Jean, Vlaski, Marija, Lafarge, Xavier, Dazey, Bernard, Robert-Richard, Elodie, Mazurier, Frédéric, Boiron, Jean-Michel

“…We developed a clinical-scale cord blood (CB) cell ex vivo procedure to enable an extensive expansion of committed progenitors--colony-forming cells (CFCs)…”
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Targeting the RNA m6A Reader YTHDF2 Selectively Compromises Cancer Stem Cells in Acute Myeloid Leukemia by Paris, Jasmin, Morgan, Marcos, Campos, Joana, Spencer, Gary J., Shmakova, Alena, Ivanova, Ivayla, Mapperley, Christopher, Lawson, Hannah, Wotherspoon, David A., Sepulveda, Catarina, Vukovic, Milica, Allen, Lewis, Sarapuu, Annika, Tavosanis, Andrea, Guitart, Amelie V., Villacreces, Arnaud, Much, Christian, Choe, Junho, Azar, Ali, van de Lagemaat, Louie N., Vernimmen, Douglas, Nehme, Ali, Mazurier, Frederic, Somervaille, Tim C.P., Gregory, Richard I., O’Carroll, Dónal, Kranc, Kamil R.

“…Acute myeloid leukemia (AML) is an aggressive clonal disorder of hematopoietic stem cells (HSCs) and primitive progenitors that blocks their myeloid…”
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XPC beyond nucleotide excision repair and skin cancers by Zebian, Abir, Shaito, Abdullah, Mazurier, Frédéric, Rezvani, Hamid Reza, Zibara, Kazem

“…Xeroderma pigmentosum group C (XPC) has been known as a DNA damage recognition factor of bulky adducts and as an initiator of global genome nucleotide excision…”
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Disruption of gap junctions attenuates acute myeloid leukemia chemoresistance induced by bone marrow mesenchymal stromal cells by Kouzi, Farah, Zibara, Kazem, Bourgeais, Jerome, Picou, Frederic, Gallay, Nathalie, Brossaud, Julie, Dakik, Hassan, Roux, Benjamin, Hamard, Sophie, Le Nail, Louis-Romee, Hleihel, Rita, Foucault, Amelie, Ravalet, Noemie, Rouleux-Bonnin, Florence, Gouilleux, Fabrice, Mazurier, Frederic, Bene, Marie C., Akl, Haidar, Gyan, Emmanuel, Domenech, Jorge, El-Sabban, Marwan, Herault, Olivier

“…The bone marrow (BM) niche impacts the progression of acute myeloid leukemia (AML) by favoring the chemoresistance of AML cells. Intimate interactions between…”
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Hypoxia and Hypoxia-Inducible Factors in Leukemias by Deynoux, Margaux, Sunter, Nicola, Hérault, Olivier, Mazurier, Frédéric

“…Despite huge improvements in the treatment of leukemia, the percentage of patients suffering relapse still remains significant. Relapse most often results from…”
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Targeting chronic myeloid leukemia stem cells with the hypoxia-inducible factor inhibitor acriflavine by Cheloni, Giulia, Tanturli, Michele, Tusa, Ignazia, Ho DeSouza, Ngoc, Shan, Yi, Gozzini, Antonella, Mazurier, Fréderic, Rovida, Elisabetta, Li, Shaoguang, Dello Sbarba, Persio

“…Chronic myeloid leukemia (CML) is a hematopoietic stem cell (HSC)-driven neoplasia characterized by expression of the constitutively active tyrosine kinase…”
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SCL/TAL1 expression level regulates human hematopoietic stem cell self-renewal and engraftment by Reynaud, Damien, Ravet, Emmanuel, Titeux, Monique, Mazurier, Frédéric, Rénia, Laurent, Dubart-Kupperschmitt, Anne, Roméo, Paul-Henri, Pflumio, Françoise

“…The fate of hematopoietic stem cells (HSCs) is regulated through a combinatorial action of proteins that determine their self-renewal and/or their commitment…”
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Targeting Reactive Oxygen Species Metabolism to Induce Myeloma Cell Death by Caillot, Mélody, Dakik, Hassan, Mazurier, Frédéric, Sola, Brigitte

“…Multiple myeloma (MM) is a common hematological disease characterized by the accumulation of clonal malignant plasma cells in the bone marrow. Over the past…”
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HIF-2α Protects Human Hematopoietic Stem/Progenitors and Acute Myeloid Leukemic Cells from Apoptosis Induced by Endoplasmic Reticulum Stress by Rouault-Pierre, Kevin, Lopez-Onieva, Lourdes, Foster, Katie, Anjos-Afonso, Fernando, Lamrissi-Garcia, Isabelle, Serrano-Sanchez, Martin, Mitter, Richard, Ivanovic, Zoran, de Verneuil, Hubert, Gribben, John, Taussig, David, Rezvani, Hamid Reza, Mazurier, Frédéric, Bonnet, Dominique

“…Hematopoietic stem and progenitor cells (HSPCs) are exposed to low levels of oxygen in the bone marrow niche, and hypoxia-inducible factors (HIFs) are the main…”
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HIF-1α in Epidermis: Oxygen Sensing, Cutaneous Angiogenesis, Cancer, and Non-Cancer Disorders by Rezvani, Hamid R., Ali, Nsrein, Nissen, Lars J., Harfouche, Ghida, de Verneuil, Hubert, Taïeb, Alain, Mazurier, Frédéric

“…Besides lung, postnatal human epidermis is the only epithelium in direct contact with atmospheric oxygen. Skin epidermal oxygenation occurs mostly through…”
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XPC multifaceted roles beyond DNA damage repair: p53-dependent and p53-independent functions of XPC in cell fate decisions by Zebian, Abir, El-Dor, Maya, Shaito, Abdullah, Mazurier, Frédéric, Rezvani, Hamid Reza, Zibara, Kazem

“…Xeroderma pigmentosum group C protein (XPC) acts as a DNA damage recognition factor for bulky adducts and as an initiator of global genome nucleotide excision…”
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Helicobacter pylori Infection Recruits Bone Marrow−Derived Cells That Participate in Gastric Preneoplasia in Mice by Varon, Christine, Dubus, Pierre, Mazurier, Frédéric, Asencio, Corinne, Chambonnier, Lucie, Ferrand, Jonathan, Giese, Alban, Senant–Dugot, Nathalie, Carlotti, Martina, Mégraud, Francis

“…Background & Aims Studies in animal models have shown that bone marrow−derived cells (BMDC) could be involved in the formation of carcinomas of the upper…”
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