Search Results - "Mazur, Christopher"

P-glycoprotein inhibition by the agricultural pesticide propiconazole and its hydroxylated metabolites: Implications for pesticide–drug interactions by Mazur, Christopher S., Marchitti, Satori A., Zastre, Jason

“…•Propiconazole and CYP450 metabolites inhibited P-gp transport in membrane vesicles.•Propiconazole acts as an inhibitor of P-gp rather than a…”
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Human and rat ABC transporter efflux of bisphenol a and bisphenol a glucuronide: interspecies comparison and implications for pharmacokinetic assessment by Mazur, Christopher S, Marchitti, Satori A, Dimova, Mira, Kenneke, John F, Lumen, Annie, Fisher, Jeff

“…Significant interspecies differences exist between human and rodent with respect to absorption, distribution, and excretion of bisphenol A (BPA) and its…”
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Differences between Human and Rat Intestinal and Hepatic Bisphenol A Glucuronidation and the Influence of Alamethicin on In Vitro Kinetic Measurements by MAZUR, Christopher S, KENNEKE, John F, HESS-WILSON, Janet K, LIPSCOMB, John C

“…The extent to which membrane-disrupting agents, such as alamethicin, may alter cofactor transport and influence in vitro kinetic measurements of…”
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Inhibition of the Human ABC Efflux Transporters P-gp and BCRP by the BDE-47 Hydroxylated Metabolite 6-OH-BDE-47: Considerations for Human Exposure by Marchitti, Satori A, Mazur, Christopher S, Dillingham, Caleb M, Rawat, Swati, Sharma, Anshika, Zastre, Jason, Kenneke, John F

“…High body burdens of polybrominated diphenyl ethers (PBDEs) in infants and young children have led to increased concern over their potential impact on human…”
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Cross-Species Comparison of Conazole Fungicide Metabolites Using Rat and Rainbow Trout (Onchorhynchus mykiss) Hepatic Microsomes and Purified Human CYP 3A4 by Mazur, Christopher S, Kenneke, John F

“…Ecological risk assessment frequently relies on cross-species extrapolation to predict acute toxicity from chemical exposures. A major concern for…”
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Enantioselective Microbial Transformation of the Phenylpyrazole Insecticide Fipronil in Anoxic Sediments by Jones, W. Jack, Mazur, Christopher S, Kenneke, John F, Garrison, A. Wayne

“…Fipronil, a chiral insecticide, was biotransformed initially to fipronil sulfide in anoxic sediment slurries following a short lag period. Sulfidogenic or…”
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Mechanistic Approach to Understanding the Toxicity of the Azole Fungicide Triadimefon to a Nontarget Aquatic Insect and Implications for Exposure Assessment by Kenneke, John F, Mazur, Christopher S, Kellock, Kristen A, Overmyer, Jay P

“…Mechanistic and stereoselective based in vitro metabolism assays were utlilized to gain insight into the toxic mode of action of the 1,2,4-triazole fungicide,…”
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Mechanistic Investigation of the Noncytochrome P450-Mediated Metabolism of Triadimefon to Triadimenol in Hepatic Microsomes by Kenneke, John F, Mazur, Christopher S, Ritger, Susan E, Sack, Thomas J

“…Recently, much emphasis has been placed on understanding the toxic mode of action of the 1,2,4-triazole fungicides (i.e., conazoles) in an effort to improve…”
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Contrasting Influence of NADPH and a NADPH-Regenerating System on the Metabolism of Carbonyl-Containing Compounds in Hepatic Microsomes by MAZUR, Christopher S, KENNEKE, John F, GOLDSMITH, Michael-Rock, BROWN, Cather

“…Carbonyl containing xenobiotics may be susceptible to NADPH-dependent cytochrome P450 (P450) and carbonyl-reduction reactions. In vitro hepatic microsome…”
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In Vitro Metabolism of the Fungicide and Environmental Contaminant trans-bromuconazole and Implications for Risk Assessment by Mazur, Christopher S., Kenneke, John F., Tebes-Stevens, Caroline, Okino, Miles S., Lipscomb, John C.

“…trans-Bromuconazole is a chiral chemical representative of a class of triazole derivatives known to inhibit specific fungal cytochrome P-450 (CYP) reactions…”
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Hydrogen Concentrations in Sulfate-Reducing Estuarine Sediments during PCE Dehalogenation by Mazur, Christopher S, Jones, W. Jack

“…Despite recent progress made evaluating the role of hydrogen (H2) as a key electron donor in the anaerobic remediation of chloroethenes, few studies have…”
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H2 consumption during the microbial reductive dehalogenation of chlorinated phenols and tetrachloroethene by MAZUR, Christopher S, JONES, W. Jack, TEBES-STEVENS, Caroline

“…Competition for molecular hydrogen exists among hydrogen-utilizing microorganisms in anoxic environments, and evidence suggests that lower hydrogen…”
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Efficacy and tolerability of a double‐conjugated retinoid cream vs 1.0% retinol cream or 0.025% tretinoin cream in subjects with mild to severe photoaging by McDaniel, David H, Mazur, Christopher, Wortzman, Mitchell S, Nelson, Diane B

“…Summary Background Topical retinoids are used to treat the visible signs of photoaging. While efficacious, they are irritating. Objective Evaluate the…”
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In Vitro Metabolism of the Fungicide and Environmental Contaminant trans-Bromuconazole and Implications for Risk Assessment by Mazur, Christopher S, Kenneke, John F, Tebes-Stevens, Caroline, Okino, Miles S, Lipscomb, John C

“…In vitro metabolism of the fungicide and environmental contaminant trans-bromuconazole and implications for risk assessment were presented. Kinetic parameters…”
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H sub(2) Consumption During the Microbial Reductive Dehalogenation of Chlorinated Phenols and Tetrachloroethene by Mazur, Christopher S, Jones, W J, Tebes-Stevens, Caroline

“…Hydrogen-utilizing microorganisms in anoxic environments tend to compete for available molecular hydrogen. Findings from tests have indicated that lower…”
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Use of ground-penetrating radar to identify geological discontinuities by using lithologic differences by Mazur, Christopher George

“…Rock units in east Texas are alternating Eocene sands and mudstones. Units having similar lithology are difficult to distinguish in the field, especially if…”
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An Electrical Mine Monitoring System Utilizing the IEC 61850 Standard by Mazur, David Christopher

“…Motor control assets are foundational elements in many industrial operations. In the mining industry, these assets primarily consist of motor control centers…”
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Use of ground-penetrating radar to identify geological discontinuities by using lithologic differences by Mazur, Christopher George

“…Rock units in east Texas are alternating Eocene sands and mudstones. Units having similar lithology are difficult to distinguish in the field, especially if…”
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The microbial transformations of the herbicides dicamba and picloram under sulfidogenic and fermentative/methanogenic conditions by Mazur, Christopher S

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THE NEW NEWSWEEK: You love it. You hate it. Either way, you have strong—quite strong— opinions about what we're doing. Which is exactly what we want by Mazur, Christopher D, Nemecek, Carl, Gillis, Linda, Katz, Barbara, Lorch, Harriet R

“…Ever since Obama started his "change" campaign, everything must be changed. Why? Our country has become "change crazy," and NEWSWEEK's new format is an example…”
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