Search Results - "Mazumder, Thomas"

Population Diversity at the Single-Cell Level by Gordon, M. Grace, Kathail, Pooja, Choy, Bryson, Kim, Min Cheol, Mazumder, Thomas, Gearing, Melissa, Ye, Chun Jimmie

“…Population-scale single-cell genomics is a transformative approach for unraveling the intricate links between genetic and cellular variation. This approach is…”
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Multi-Omic Profiling of Macrophages Lacking Tet2 or Dnmt3a Reveals Mechanisms of Hyper-Inflammation in Clonal Hematopoiesis by Rodrigues, Kameron B, Gopakumar, Jayakrishnan, Weng, Ziming, Mitchell, Shaneice Renee, Maurer, Margaret, Nachun, Daniel, Eulalio, Tiffany, Estrada, Dorothy, Mazumder, Thomas, Ma, Lisa, Montgomery, Stephen, Jaiswal, Siddhartha

“…Introduction Clonal Hematopoiesis of Indeterminate Potential (CHIP) is a source of age-associated inflammation, caused by somatic mutations in bone marrow stem…”
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Mitigation of chromosome loss in clinical CRISPR-Cas9-engineered T cells by Tsuchida, Connor A., Brandes, Nadav, Bueno, Raymund, Trinidad, Marena, Mazumder, Thomas, Yu, Bingfei, Hwang, Byungjin, Chang, Christopher, Liu, Jamin, Sun, Yang, Hopkins, Caitlin R., Parker, Kevin R., Qi, Yanyan, Hofman, Laura, Satpathy, Ansuman T., Stadtmauer, Edward A., Cate, Jamie H.D., Eyquem, Justin, Fraietta, Joseph A., June, Carl H., Chang, Howard Y., Ye, Chun Jimmie, Doudna, Jennifer A.

“…CRISPR-Cas9 genome editing has enabled advanced T cell therapies, but occasional loss of the targeted chromosome remains a safety concern. To investigate…”
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