Search Results - "Mazumder, Purba"

29-OR: Diabetic Wound Keratinocytes Induce Macrophage JMJD3–Mediated Nlrp3 Expression by WOLF-FORTUNE, SONYA, MOON, JADIE, JOSHI, AMRITA, MAZUMDER, PURBA, BARRETT, EMILY, MANGUM, KEVIN D., GALLAGHER, KATHERINE

“…Macrophage (Mφ) plasticity is critical for normal wound repair; however, type 2 diabetic (T2D) wound Mφs display a delayed chronic inflammatory state that…”
Get full text

The Histone Methyltransferase Whsc1 Regulates Tgfb-driven Macrophage to Myofibroblast Transition During Normal Wound Healing by Mangum, Kevin, Joshi, Amrita, Erturk, Asuman, Mazumder, Purba, Barrett, Emily, Wolf, Sonya, Obi, Andrea, Kunkel, Steven, Davis, Frank, Gallagher, Katherine

Get full text

458-P: Proinflammatory Macrophage Phenotype Modulates Vascular Smooth Muscle Cell Differentiation via the Histone Demethylase JMJD3 by MANGUM, KEVIN D., JOSHI, AMRITA, MAZUMDER, PURBA, WOLF-FORTUNE, SONYA, BARRETT, EMILY, MOORE, BETHANY, DAVIS, FRANK M., GALLAGHER, KATHERINE

“…Patients with diabetes are at increased risk of a multitude of vascular diseases, including atherosclerosis, which is driven by macrophage-mediated…”
Get full text

IL-17A-mediated JMJD3 regulation of integrin alpha 3 gene expression alters migration of diabetic keratinocytes and impairs wound repair by Moon, Jadie Yoonjoo, Wolf, Sonya, Audu, Christopher, Melvin, William, Joshi, Amrita, Mangum, Kevin, Barrett, Emily, Davis, Frank, Mazumder, Purba, Rocco, Sabrina, Erturk, Ilkim, Gallagher, Katherine

“…Abstract Keratinocytes are key structural cells in cell migration during wound repair. Keratinocyte migration is dysfunctional in diabetes and results in…”
Get full text

Diabetic wound macrophage IL6 drives fibroblast dysfunction via the histone methyltransferase, SETDB2 by Joshi, Amrita D, Barrett, Emily C, Mangum, Kevin D, Mazumder, Purba, Rocco, Sabrina, Erturk, Asuman, Kai, Rohan, Moon, Jadie Yoonjoo, Wolf, Sonya, Gallagher, Katherine

“…Abstract Interactions between innate immune cells and structural cells are vital to proper tissue repair and regeneration after injury. Under pathologic…”
Get full text

IL-17A-mediated JMJD3 regulation of Cxcl1 gene expression in diabetic keratinocytes increases neutrophil recruitment and impairs wound repair by Moon, Jadie, Wolf, Sonya, Audu, Chris, Melvin, William, Joshi, Amrita, Mangum, Kevin, Barrett, Emily, Bauer, Tyler, Shadiow, James, Mazumder, Purba, Rocco, Sabrina, Erturk, Ilkim, Saldana de Jimenez, Gabriela, Moore, Bethany, Davis, Frank, Obi, Andrea, Gallagher, Katherine

“…Abstract Diabetic keratinocytes display an overexpression of chemokines that contribute to prolonged inflammation and non-healing. Using sequencing, we…”
Get full text

The histone methyltransferase Whsc1 regulates TGFβ-driven macrophage to myofibroblast transition by Mangum, Kevin D, Joshi, Amrita D, Melvin, William J, Mazumder, Purba, Erturk, Asuman, Wolf, Sonya, Barrett, Emily C, Moon, Jadie Yoonjoo, Obi, Andrea, Kunkel, Steven L, Moore, Bethany B, Gallagher, Katherine

“…Abstract In normal wound healing, macrophages regulate early and late inflammation, allowing for resolution of tissue injury and subsequent healing. During…”
Get full text

The histone methyltransferase mixed-lineage-leukemia-1 drives T cell phenotype via notch signaling in diabetic tissue repair by Melvin, William J, Bauer, Tyler M, Magnum, Kevin D, Audu, Christopher O, Shadiow, James, Barrett, Emily, Joshi, Amrita, Moon, Jadie Y, Bogel, Rachel, Mazumder, Purba, Wolf, Sonya J, Kunkel, Steven, Gudjonsson, Johann E, Davis, Frank M, Gallagher, Katherine A

“…Immune cell mediated inflammation is important in normal tissue regeneration but can be pathologic in diabetic wounds. Limited literature exists on the role of…”
Get full text