Search Results - "Mazo, Alexander"

Epigenetic regulation affects gene amplification in Drosophila development by Kohzaki, Hidetsugu, Asano, Maki, Murakami, Yota, Mazo, Alexander

“…In Drosophila melanogaster, in response to developmental transcription factors, and by repeated initiation of DNA replication of four chorion genes, ovarian…”
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Delayed Accumulation of H3K27me3 on Nascent DNA Is Essential for Recruitment of Transcription Factors at Early Stages of Stem Cell Differentiation by Petruk, Svetlana, Cai, Jingli, Sussman, Robyn, Sun, Guizhi, Kovermann, Sina K., Mariani, Samanta A., Calabretta, Bruno, McMahon, Steven B., Brock, Hugh W., Iacovitti, Lorraine, Mazo, Alexander

“…Recruitment of transcription factors (TFs) to repressed genes in euchromatin is essential to activate new transcriptional programs during cell differentiation…”
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Transcription of bxd Noncoding RNAs Promoted by Trithorax Represses Ubx in cis by Transcriptional Interference by Petruk, Svetlana, Sedkov, Yurii, Riley, Kristen M., Hodgson, Jacob, Schweisguth, Francois, Hirose, Susumu, Jaynes, James B., Brock, Hugh W., Mazo, Alexander

“…Much of the genome is transcribed into long noncoding RNAs (ncRNAs). Previous data suggested that bithoraxoid ( bxd) ncRNAs of the Drosophila bithorax complex…”
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Structure of Nascent Chromatin Is Essential for Hematopoietic Lineage Specification by Petruk, Svetlana, Mariani, Samanta A., De Dominici, Marco, Porazzi, Patrizia, Minieri, Valentina, Cai, Jingli, Iacovitti, Lorraine, Flomenberg, Neal, Calabretta, Bruno, Mazo, Alexander

“…The role of chromatin structure in lineage commitment of multipotent hematopoietic progenitors (HPCs) is presently unclear. We show here that CD34+ HPCs…”
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Fibrosis-the tale of H3K27 histone methyltransferases and demethylases by Basta, Morgan D, Petruk, Svetlana, Mazo, Alexander, Walker, Janice L

“…Fibrosis, or excessive scarring, is characterized by the emergence of alpha-smooth muscle actin (αSMA)-expressing myofibroblasts and the excessive accumulation…”
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Detection of RNA-DNA association by a proximity ligation-based method by Petruk, Svetlana, Fenstermaker, Tyler K., Black, Kathryn L., Brock, Hugh W., Mazo, Alexander

“…We describe a proximity ligation assay (PLA)-based method of assessing association of DNA and RNA in single cells during the cell cycle. Pulse-labeling of DNA…”
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Changes in nascent chromatin structure regulate activation of the pro-fibrotic transcriptome and myofibroblast emergence in organ fibrosis by Basta, Morgan D., Petruk, Svetlana, Summer, Ross, Rosenbloom, Joel, Wermuth, Peter J., Macarak, Edward, Levin, Alex V., Mazo, Alexander, Walker, Janice L.

“…Cell reprogramming to a myofibroblast responsible for the pathological accumulation of extracellular matrix is fundamental to the onset of fibrosis. Here, we…”
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Transcriptional interference: an unexpected layer of complexity in gene regulation by Mazo, Alexander, Hodgson, Jacob W, Petruk, Svetlana, Sedkov, Yurii, Brock, Hugh W

“…Much of the genome is transcribed into long untranslated RNAs, mostly of unknown function. Growing evidence suggests that transcription of sense and antisense…”
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Modulation of heat shock gene expression by the TAC1 chromatin-modifying complex by Mazo, Alexander, Smith, Sheryl T, Petruk, Svetlana, Sedkov, Yurii, Cho, Elizabeth, Tillib, Sergei, Canaani, Eli

“…Rapid induction of the Drosophila melanogaster heat shock gene hsp70 is achieved through the binding of heat shock factor (HSF) to heat shock elements (HSEs)…”
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Additional sex combs interacts with enhancer of zeste and trithorax and modulates levels of trimethylation on histone H3K4 and H3K27 during transcription of hsp70 by Li, Taosui, Hodgson, Jacob W, Petruk, Svetlana, Mazo, Alexander, Brock, Hugh W

“…Maintenance of cell fate determination requires the Polycomb group for repression; the trithorax group for gene activation; and the enhancer of trithorax and…”
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Mechanism of transition to turbulence in a circular cylinder wake in a channel by Molochnikov, Valery, Mazo, Alexander, Okhotnikov, Dmitriy, Goltsman, Anna

“…Transition to turbulence in the circular cylinder wake has been studied experimentally and numerically at growing Reynolds number. Good agreement of…”
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Methylation at lysine 4 of histone H3 in ecdysone-dependent development of Drosophila by Mazo, Alexander, Sedkov, Yurii, Cho, Elizabeth, Petruk, Svetlana, Cherbas, Lucy, Smith, Sheryl T, Jones, Richard S, Cherbas, Peter, Canaani, Eli, Jaynes, James B

“…Steroid hormones fulfil important functions in animal development. In Drosophila, ecdysone triggers moulting and metamorphosis through its effects on gene…”
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Association of trxG and PcG proteins with the bxd maintenance element depends on transcriptional activity by Petruk, Svetlana, Smith, Sheryl T, Sedkov, Yurii, Mazo, Alexander

“…Polycomb group (PcG) and trithorax group (trxG) proteins act in an epigenetic fashion to maintain active and repressive states of expression of the Hox and…”
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A Motif within SET-Domain Proteins Binds Single-Stranded Nucleic Acids and Transcribed and Supercoiled DNAs and Can Interfere with Assembly of Nucleosomes by Krajewski, Wladyslaw A., Nakamura, Tatsuya, Mazo, Alexander, Canaani, Eli

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Numerical modeling of local effects on the petroleum reservoir using fixed streamtubes for typical waterflooding schemes by Potashev, Konstantin A., Mazo, Alexander B.

“…The difficulty of numerical modeling of areal methods of flows redistribution in the oil reservoir is the need for detailed resolution of local hydrodynamic…”
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The C-terminal SET domains of All-1 and TRITHORAX interact with the INI1 and SNR1 proteins, components of the SWI/SNF complex by Rozenblatt-Rosen, O. (Weizmann Institute of Science, Rehovot, Israel.), Rozovskaia, T, Burakov, D, Sedkov, Y, Tillib, S, Blechman, J, Nakamura, T, Croice, C.M, Mazo, A, Canaani, E

“…The ALL-1 gene was discovered by virtue of its involvement in human acute leukemia. Its Drosophila homolog trithorax (trx) is a member of the trx-Polycomb gene…”
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A Model for Initiation of Mosaic HOX Gene Expression Patterns by Non-Coding RNAs in Early Embryos by Petruk, Svetlana, Sedkov, Yurii, Brock, Hugh W., Mazo, Alexander

“…There is growing appreciation for the role of non-coding (nc) RNA in regulation of HOX genes of Drosophila. Our data suggest that current models for activation…”
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huASH1 Protein, a Putative Transcription Factor Encoded by a Human Homologue of the Drosophila ash1 Gene, Localizes to Both Nuclei and Cell-Cell Tight Junctions by Nakamura, Tatsuya, Blechman, Janna, Tada, Shinichiro, Rozovskaia, Tanya, Itoyama, Takahiro, Bullrich, Florencia, Mazo, Alexander, Croce, Carlo M., Geiger, Benjamin, Canaani, Eli

“…During animal development, regions of the embryo become committed to position-specific identities, which are determined by spatially restricted expression of…”
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Trithorax- and Polycomb-Group Response Elements within an Ultrabithorax Transcription Maintenance Unit Consist of Closely Situated but Separable Sequences by Tillib, Sergei, Petruk, Svetlana, Sedkov, Yurii, Kuzin, Alexander, Fujioka, Miki, Goto, Tadaatsu, Mazo, Alexander

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Identification and Characterization of the ARP1 Gene, a Target for the Human Acute Leukemia ALL1 Gene by Arakawa, Hirofumi, Nakamura, Tatsuya, Zhadanov, Alexander B., Fidanza, Vincenzo, Yano, Takahiro, Bullrich, Florencia, Shimizu, Masayoshi, Blechman, Janna, Mazo, Alexander, Canaani, Eli, Croce, Carlo M.

“…ALL1, the human homologue of Drosophila trithorax, is directly involved in human acute leukemias associated with abnormalities at 11q23. Using the differential…”
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