Search Results - "Mazloom, Anisha"
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Implementing Pediatric Surviving Sepsis Campaign Guidelines: Improving Compliance With Lactate Measurement in the PICU
Published in Critical care explorations (01-04-2023)“…The 2020 pediatric Surviving Sepsis Campaign (pSSC) recommends measuring lactate during the first hour of resuscitation for severe sepsis/shock. We aimed to…”
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CTA095, a novel Etk and Src dual inhibitor, induces apoptosis in prostate cancer cells and overcomes resistance to Src inhibitors
Published in PloS one (15-08-2013)“…Etk is a non-receptor tyrosine kinase, which provides a strong survival signal in human prostate cancer cells. Src, another tyrosine kinase that…”
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1262: IMPLEMENTING PEDIATRIC SURVIVING SEPSIS CAMPAIGN GUIDELINES: IMPROVING MEASUREMENT OF LACTATE
Published in Critical care medicine (01-01-2022)Get full text
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Using the Electronic Medical Record (EMR) to Reduce Central Line Associated Blood Stream Infections (CLABSI) Rates in the Pediatric Intensive Care Unit by Improving Maintenance Bundle Compliance
Published in Pediatrics (Evanston) (01-08-2019)“…Purpose: Central line associated blood stream infections (CLABSIs) prolong hospitalizations, increase exposure to infectious disease and antibiotics, and…”
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Ensuring No Death Is Ignored: Development of a Hospital Mortality Review and Notification System
Published in Pediatrics (Evanston) (01-10-2023)“…BACKGROUND AND OBJECTIVES Standardized review of mortalities may identify potential system improvements. We designed a hospitalwide identification, review, and…”
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Molecular characteristics of CTA056, a novel interleukin-2-inducible T-cell kinase inhibitor that selectively targets malignant T cells and modulates oncomirs
Published in Molecular pharmacology (01-11-2012)“…Interleukin-2-inducible T-cell kinase (Itk) is a member of the Btk (Bruton's tyrosine kinase) family of tyrosine kinases. Itk plays an important role in normal…”
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Discovery and characterization of a high-affinity and high-specificity peptide ligand LXY30 for in vivo targeting of alpha 3 integrin-expressing human tumors
Published in EJNMMI research (01-12-2016)“…alpha 3 beta 1 integrin is overexpressed in several types of human cancer and is associated with poor prognosis, metastasis, and resistance to cancer…”
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Discovery and characterization of a high-affinity and high-specificity peptide ligand LXY30 for in vivo targeting of α3 integrin-expressing human tumors
Published in EJNMMI research (01-12-2016)“…Background α3β1 integrin is overexpressed in several types of human cancer and is associated with poor prognosis, metastasis, and resistance to cancer…”
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Abstract 368: Development of a highly potent and non-invasive optical imaging agent for glioblastoma
Published in Cancer research (Chicago, Ill.) (15-04-2012)“…Abstract Using the “one-bead one-compound” (OBOC) combinatorial library approach, we have previously identified a peptide ligand LXY1, cyclic…”
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Abstract 3580: Discovery and SAR study of a novel and potent Itk inhibitor as a targeted therapeutic agent for T-cell lymphoma and leukemia
Published in Cancer research (Chicago, Ill.) (15-04-2011)“…Abstract Itk (IL2-inducible T-cell kinase) is a non-receptor protein tyrosine kinase. It is selectively expressed in T cells, Mast cells, and NK cells. It…”
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Discovery and characterization of a high-affinity and high-specificity peptide ligand LXY30 for in vivo targeting of [alpha]3 integrin-expressing human tumors
Published in EJNMMI research (01-02-2016)“…Background [alpha]3[beta]1 integrin is overexpressed in several types of human cancer and is associated with poor prognosis, metastasis, and resistance to…”
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