Search Results - "Mazepa, Marshall A"
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How targeted therapy disrupts the treatment paradigm for acquired TTP: the risks, benefits, and unknowns
Published in Blood (01-08-2019)“…Insights into immune-mediated thrombotic thrombocytopenic purpura (iTTP) pathophysiology have led to novel targeted therapies. Immunomodulatory strategies…”
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The frequency of joint hemorrhages and procedures in nonsevere hemophilia A vs B
Published in Blood advances (28-08-2018)“…Data are needed on minimal factor activity (FA) levels required to prevent bleeding in hemophilia. We aimed to evaluate associations between hemophilia type…”
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Predictive Value of Schistocytes in Recurrence of Acquired Thrombotic Thrombocytopenic Purpura With Severe ADAMTS13 Deficiency at Discontinuation of Daily Therapeutic Plasma Exchange
Published in Therapeutic apheresis and dialysis (01-12-2018)“…Acquired thrombotic thrombocytopenic purpura (TTP) is characterized by microangiopathic hemolytic anemia, thrombocytopenia, and commonly ADAMTS13 deficiency…”
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The top 10 things to know about transfusion medicine before intern year: an evidence-based course for graduating medical students
Published in Blood research (01-06-2019)“…Transfusion medicine (TM) knowledge varies widely among physician trainees. In addition, there have been few instances in which curricular changes have been…”
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Men with severe hemophilia in the United States: birth cohort analysis of a large national database
Published in Blood (16-06-2016)“…The availability of longitudinal data collected prospectively from 1998 to 2011 at federally funded US hemophilia treatment centers provided an opportunity to…”
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Cardiovascular Disease and Stroke in Immune TTP-Challenges and Opportunities
Published in Journal of clinical medicine (14-09-2023)“…Advances in the management of immune thrombotic thrombocytopenic purpura (iTTP) have dramatically improved outcomes of acute TTP episodes, and TTP is now…”
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Race, rituximab, and relapse in TTP
Published in Blood (22-09-2022)“…Immune-mediated thrombotic thrombocytopenic purpura (iTTP) is characterized by recurring episodes of thrombotic microangiopathy, causing ischemic organ…”
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Major adverse cardiovascular events in survivors of immune‐mediated thrombotic thrombocytopenic purpura
Published in American journal of hematology (01-12-2021)“…Cardiovascular disease is a leading cause of death in survivors of immune‐mediated thrombotic thrombocytopenic purpura (iTTP), but the epidemiology of major…”
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Maternal and fetal outcomes of pregnancy occurring after a diagnosis of immune-mediated thrombotic thrombocytopenic purpura
Published in Annals of hematology (01-10-2022)“…Pregnancy is a well-established trigger for a first episode or relapse of immune thrombotic thrombocytopenic purpura (iTTP). Other outcomes of subsequent…”
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Therapeutic plasma exchange taper does not decrease exacerbations in immune thrombotic thrombocytopenic purpura patients
Published in Transfusion (Philadelphia, Pa.) (01-08-2020)“…BACKGROUND Despite rapid and intensive treatments with therapeutic plasma exchange (TPE) and immunosuppression, immune thrombotic thrombocytopenic purpura…”
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Taking Empiricism out of Immune Thrombotic Thrombocytopenic Purpura: Current and Future Treatment Strategies
Published in Transfusion medicine reviews (01-10-2019)“…Immune thrombotic thrombocytopenic purpura (iTTP) is a chronically relapsing, humorally-mediated autoimmune disorder characterized by unpredictable episodes of…”
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Opioid exposure in haemophilia patients is common and underreported
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01-03-2020)“…Introduction In an era of increased opioid awareness, data on opioid exposure in haemophilia patients are lacking. Aim The objectives of this study were to (a)…”
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The Impact of an Undergraduate Biology Class on Donor Recruitment at a Hospital-Based Blood Donor Center
Published in American journal of clinical pathology (08-02-2020)“…Abstract Objectives A biology class, BIOL 294H, taught undergraduates about platelet donation while partnering with the University of North Carolina’s (UNC’s)…”
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Treatment of acquired Thrombotic Thrombocytopenic Purpura in the U.S. remains heterogeneous: Current and future points of clinical equipoise
Published in Journal of clinical apheresis (01-06-2018)“…Background The purpose of this survey was to describe current practices in the U.S. for treatment of acquired Thrombotic Thrombocytopenic Purpura (TTP),…”
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How we approach an acquired thrombotic thrombocytopenic purpura patient
Published in Transfusion (Philadelphia, Pa.) (01-10-2014)“…Acquired thrombotic thrombocytopenic purpura (TTP) is a disease characterized by microangiopathic hemolytic anemia and thrombocytopenia, in addition to…”
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Pathology consultation on electronic crossmatch
Published in American journal of clinical pathology (01-05-2014)“…The full crossmatch is traditionally the final step in compatibility testing, acting as a serologic double check for ABO compatibility and unexpected RBC…”
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Heparin‐induced thrombocytopenia associated with collection of hematopoietic progenitor cells by apheresis
Published in Journal of clinical apheresis (01-01-2020)“…Heparin‐induced thrombocytopenia (HIT) can occur following exposure to heparin and is characterized by thrombocytopenia with increased risk for thrombosis…”
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Monitoring therapeutic apheresis utilization: Database versus registry
Published in Journal of clinical apheresis (01-06-2017)Get full text
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