Search Results - "Mazal, Alejandro"
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Experimental Set-up for FLASH Proton Irradiation of Small Animals Using a Clinical System
Published in International journal of radiation oncology, biology, physics (01-11-2018)“…Recent in vivo investigations have shown that short pulses of electrons at very high dose rates (FLASH) are less harmful to healthy tissues but just as…”
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2
EPID based in vivo dosimetry system: clinical experience and results
Published in Journal of applied clinical medical physics (01-05-2016)“…Mandatory in several countries, in vivo dosimetry has been recognized as one of the next milestones in radiation oncology. Our department has implemented…”
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3
Radical Production with Pulsed Beams: Understanding the Transition to FLASH
Published in International journal of molecular sciences (03-11-2022)“…Ultra-high dose rate (UHDR) irradiation regimes have the potential to spare normal tissue while keeping equivalent tumoricidal capacity than conventional dose…”
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4
Practice Patterns Analysis of Ocular Proton Therapy Centers: The International OPTIC Survey
Published in International journal of radiation oncology, biology, physics (01-05-2016)“…Purpose To assess the planning, treatment, and follow-up strategies worldwide in dedicated proton therapy ocular programs. Methods and Materials Ten centers…”
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Biological and Mechanical Synergies to Deal With Proton Therapy Pitfalls: Minibeams, FLASH, Arcs, and Gantryless Rooms
Published in Frontiers in oncology (21-01-2021)“…Proton therapy has advantages and pitfalls comparing with photon therapy in radiation therapy. Among the limitations of protons in clinical practice we can…”
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The prediction of output factors for spread-out proton Bragg peak fields in clinical practice
Published in Physics in medicine & biology (21-12-2005)“…The reliable prediction of output factors for spread-out proton Bragg peak (SOBP) fields in clinical practice remained unrealized due to a lack of a consistent…”
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7
Case study thoracic radiotherapy in an elderly patient with pacemaker: The issue of pacing leads
Published in Medical dosimetry : official journal of the American Association of Medical Dosimetrists (2012)“…Abstract To assess clinical outcome of patients with pacemaker treated with thoracic radiation therapy for T8-T9 paravertebral chloroma. A 92-year-old male…”
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8
FLASH and minibeams in radiation therapy: the effect of microstructures on time and space and their potential application to protontherapy
Published in British journal of radiology (01-03-2020)“…After years of lethargy, studies on two non-conventional microstructures in time and space of the beams used in radiation therapy are enjoying a huge revival…”
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The current status of preclinical proton FLASH radiation and future directions
Published in Medical physics (Lancaster) (01-03-2022)“…We review the current status of proton FLASH experimental systems, including preclinical physical and biological results. Technological limitations on…”
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10
A quantitative FLASH effectiveness model to reveal potentials and pitfalls of high dose rate proton therapy
Published in Medical physics (Lancaster) (01-03-2022)“…Purpose In ultrahigh dose rate radiotherapy, the FLASH effect can lead to substantially reduced healthy tissue damage without affecting tumor control. Although…”
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11
Assessment of the Quirónsalud Proton Therapy Centre Accelerator for Single Event Effects Testing
Published in IEEE transactions on nuclear science (01-08-2024)“…High-energy proton testing is used for single-event effect (SEE) qualification of electronics employed in several radiation-harsh environments. Given the…”
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12
PTCOG Ocular Statement: Expert Summary of Current Practices and Future Developments in Ocular Proton Therapy
Published in International journal of radiation oncology, biology, physics (01-12-2024)“…Although rare cancers, ocular tumors are a threat to vision, quality of life, and potentially life expectancy of a patient. Ocular proton therapy (OPT) is a…”
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13
1770: On-the-fly dose reconstruction from in-beam PET activation
Published in Radiotherapy and oncology (01-05-2024)Get full text
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14
Enhancing adaptive proton therapy through CBCT images: Synthetic head and neck CT generation based on 3D vision transformers
Published in Medical physics (Lancaster) (01-07-2024)“…Background Proton therapy is a form of radiotherapy commonly used to treat various cancers. Due to its high conformality, minor variations in patient anatomy…”
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15
Material decomposition maps based calibration of dual energy CT scanners for proton therapy planning: a phantom study
Published in Physics in medicine & biology (21-02-2024)“…We introduce a new calibration method for dual energy CT (DECT) based on material decomposition (MD) maps, specifically iodine and water MD maps. The aim of…”
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Technical note: Measurement of the bunch structure of a clinical proton beam using a SiPM coupled to a plastic scintillator with an optical fiber
Published in Medical physics (Lancaster) (01-05-2023)“…Background Recent proposals of high dose rate plans in protontherapy as well as very short proton bunches may pose problems to current beam monitor systems…”
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Particle arc therapy: Status and potential
Published in Radiotherapy and oncology (01-10-2024)“…•The ESTRO Physics Workshop “Particle Arc Therapy: from concept to clinical reality” took place October 7th-8th, 2022 in Lisbon, Portugal.•There is a rising…”
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Static and rotational output variation of a tomotherapy unit
Published in Medical physics (Lancaster) (01-03-2009)“…A simple device to check the machine output in rotational mode is described. Integral and instantaneous beam output in absolute dose can be measured and…”
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Abstract P4-12-32: Intensity modulated radiotherapy (IMRT) for breast and lymph node irradiation
Published in Cancer research (Chicago, Ill.) (15-02-2020)“…Abstract Background:Since 2009, the use of IMRT for the treatment of breast cancer with lymph node involvement has been considerably growing at our…”
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Five-Fraction Proton Therapy for the Treatment of Skull Base Chordomas and Chondrosarcomas: Early Results of a Prospective Series and Description of a Clinical Trial
Published in Cancers (25-11-2023)“…(1) Background: Our purpose is to describe the design of a phase II clinical trial on 5-fraction proton therapy for chordomas and chondrosarcomas of the skull…”
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