Search Results - "Maywald, Rebecca L"
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IL-33 activates tumor stroma to promote intestinal polyposis
Published in Proceedings of the National Academy of Sciences - PNAS (12-05-2015)“…Tumor epithelial cells develop within a microenvironment consisting of extracellular matrix, growth factors, and cytokines produced by nonepithelial stromal…”
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Perturbation of semaphorin and VEGF signaling in ACDMPV lungs due to FOXF1 deficiency
Published in Respiratory research (27-07-2021)“…Alveolar capillary dysplasia with misalignment of pulmonary veins (ACDMPV) is a rare lethal congenital lung disorder in neonates characterized by severe…”
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GSDMB is increased in IBD and regulates epithelial restitution/repair independent of pyroptosis
Published in Cell (20-01-2022)“…Gasdermins are a family of structurally related proteins originally described for their role in pyroptosis. Gasdermin B (GSDMB) is currently the least studied,…”
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4
Testicular germ cell tumors arise in the absence of sex-specific differentiation
Published in Development (Cambridge) (01-05-2021)“…In response to signals from the embryonic testis, the germ cell intrinsic factor NANOS2 coordinates a transcriptional program necessary for the differentiation…”
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IGF-1R and mTOR Blockade: Novel Resistance Mechanisms and Synergistic Drug Combinations for Ewing Sarcoma
Published in JNCI : Journal of the National Cancer Institute (01-12-2016)“…Therapies cotargeting insulin-like growth factor receptor 1 (IGF-1R) and mammalian target of rapamycin (mTOR) have demonstrated remarkable, albeit short-lived,…”
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An Oral Formulation of YK-4-279: Preclinical Efficacy and Acquired Resistance Patterns in Ewing Sarcoma
Published in Molecular cancer therapeutics (01-07-2015)“…Ewing sarcoma is a transcription factor-mediated pediatric bone tumor caused by a chromosomal translocation of the EWSR1 gene and one of several genes in the…”
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