Search Results - "Maywald, Martina"
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Zinc as a Gatekeeper of Immune Function
Published in Nutrients (25-11-2017)“…After the discovery of zinc deficiency in the 1960s, it soon became clear that zinc is essential for the function of the immune system. Zinc ions are involved…”
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Zinc Signals and Immunity
Published in International journal of molecular sciences (24-10-2017)“…Zinc homeostasis is crucial for an adequate function of the immune system. Zinc deficiency as well as zinc excess result in severe disturbances in immune cell…”
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Zinc in Human Health and Infectious Diseases
Published in Biomolecules (Basel, Switzerland) (24-11-2022)“…During the last few decades, the micronutrient zinc has proven to be an important metal ion for a well-functioning immune system, and thus also for a suitable…”
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Zinc Deficiency and Zinc Supplementation in Allergic Diseases
Published in Biomolecules (Basel, Switzerland) (19-07-2024)“…In recent decades, it has become clear that allergic diseases are on the rise in both Western and developing countries. The exact reason for the increase in…”
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Influence of zinc deficiency and supplementation on NK cell cytotoxicity
Published in Journal of functional foods (01-09-2018)“…Zinc supplementation enhances NK cell activity by increasing perforin expression. Furthermore, zinc supplementation increased the interleukin (IL)-2 enhanced…”
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The Intracellular Free Zinc Level Is Vital for Treg Function and a Feasible Tool to Discriminate between Treg and Activated Th Cells
Published in International journal of molecular sciences (13-11-2018)“…The intracellular free zinc level and zinc distribution are important for cellular function. Both are highly variable and are altered due to intrinsic zinc…”
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Zinc supplementation induces CD4+CD25+Foxp3+ antigen-specific regulatory T cells and suppresses IFN-γ production by upregulation of Foxp3 and KLF-10 and downregulation of IRF-1
Published in European journal of nutrition (01-08-2017)“…Purpose The essential trace element zinc plays a fundamental role in immune function and regulation since its deficiency is associated with autoimmunity,…”
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Zinc homeostasis and immunosenescence
Published in Journal of trace elements in medicine and biology (01-01-2015)“…For more than 50 years, zinc is known to be an essential trace element, having a regulatory role in the immune system. Deficiency in zinc thus compromises…”
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Intracellular zinc during cell activation and zinc deficiency
Published in Journal of trace elements in medicine and biology (01-12-2021)“…[Display omitted] •Zinc is involved in a variety of signaling cascades as a second messenger. Cell activation is often followed by a consecutive release of…”
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Zinc supplementation plays a crucial role in T helper 9 differentiation in allogeneic immune reactions and non-activated T cells
Published in Journal of trace elements in medicine and biology (01-12-2018)“…[Display omitted] •Th9 cell differentiation is modulated by zinc signals.•Zinc supply dampens allogeneic immune reaction in MLC by hampering Th9…”
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Zinc supplementation induces CD4^sup +^CD25^sup +^Foxp3^sup +^ antigen-specific regulatory T cells and suppresses IFN-[gamma] production by upregulation of Foxp3 and KLF-10 and downregulation of IRF-1
Published in European journal of nutrition (01-08-2017)“…Purpose The essential trace element zinc plays a fundamental role in immune function and regulation since its deficiency is associated with autoimmunity,…”
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Zinc deficiency drives Th17 polarization and promotes loss of Treg cell function
Published in The Journal of nutritional biochemistry (01-01-2019)“…A high number of illnesses and disorders are connected to zinc deficiency. Equally, T cell polarization and a balance between different T helper (Th) cell…”
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Zinc supplementation augments TGF‐β1‐dependent regulatory T cell induction
Published in Molecular nutrition & food research (01-03-2017)“…Scope Regulatory T cells (Treg) play a pivotal role in immune regulation. For proper immune function, also trace elements such as zinc, and anti‐inflammatory…”
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Zinc supplementation augments TGF- beta 1-dependent regulatory T cell induction
Published in Molecular nutrition & food research (01-03-2017)“…Scope Regulatory T cells (Treg) play a pivotal role in immune regulation. For proper immune function, also trace elements such as zinc, and anti-inflammatory…”
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The Interaction of Sodium and Zinc in the Priming of T Cell Subpopulations Regarding Th17 and Treg Cells
Published in Molecular nutrition & food research (01-01-2020)“…Scope Nutrition is a critical determinant of a functional immune system. The aim of this study is to investigate the molecular mechanisms by which immune cells…”
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Zinc supplementation induces regulatory T cells by inhibition of Sirt‐1 deacetylase in mixed lymphocyte cultures
Published in Molecular nutrition & food research (01-03-2016)“…SCOPE: Zinc is an essential trace element, regulating immune function. Its deficiency results in immune dysfunction and transplant rejection. In here, a…”
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Induction of regulatory T cells in Th1-/Th17-driven experimental autoimmune encephalomyelitis by zinc administration
Published in The Journal of nutritional biochemistry (01-03-2016)“…The essential trace element zinc is indispensable for proper immune function as zinc deficiency accompanies immune defects and dysregulations like allergies,…”
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Proton‐pump inhibitors elevate infection rate in cardiothoracic surgery patients by influencing PMN function in vitro and in vivo
Published in Journal of leukocyte biology (01-04-2018)“…Proton‐pump inhibitors (PPI) as pantoprazole are highly effective acid suppressive agents that belong to the world's most sold medication. However, they are…”
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Development and validation of a ready to use cryo-EROD assay for the standardized screening of dioxins and dioxin-like compounds in foodstuffs
Published in Food and chemical toxicology (01-12-2018)“…Recent European regulations have indicated the need for new bioanalytical screening methods capable of monitoring dioxin and dioxin-like compounds in…”
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