Search Results - "Mays, Dennis"
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Motivating Self-Efficacy in Diverse Biomedical Science Post-baccalaureate and Graduate Students Through Scientific Conference Implementation
Published in Frontiers in education (Lausanne) (07-12-2021)“…Tactics to increase the number of underrepresented (UR) students in biomedical research PhD training programs have not yet translated to UR faculty numbers…”
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Making Plans for Michael: providing for a student with moderate learning difficulties in a secondary academy
Published in Support for learning (01-02-2020)“…The profile of a student with learning difficulties is described and also the learning context in 2017. Previous models of provision are then described in…”
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Erythrocyte mean corpuscular volume as a surrogate marker for 6‐thioguanine nucleotide concentration monitoring in patients with inflammatory bowel disease treated with azathioprine or 6‐mercaptopurine
Published in Inflammatory bowel diseases (01-07-2003)“…Mean corpuscular volume may correlate with erythrocyte 6‐thioguanine nucleotide concentrations in patients treated with azathioprine and 6‐mercaptourine. We…”
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Can serious reading disorders be investigated and diagnosed by secondary school SEN staff?
Published in Support for learning (01-05-2018)“…By the time they transfer to secondary school, most young people who have serious obstacles to becoming literate will have been identified. The necessary…”
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Reading for meaning; time to revisit top‐down strategies?
Published in Support for learning (01-05-2017)“…The teaching of reading is one of the consistent topics for discussion in eduvation. It exercises the minds of teachers, parents and politicians alike. This is…”
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Determination of in vivo adducts of disulfiram with mitochondrial aldehyde dehydrogenase
Published in Biochemical pharmacology (01-03-2001)“…Extensive use for disulfiram (DSF) has been found in the aversion therapy treatment of recovering alcoholics. Although it is known to irreversibly inhibit…”
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Metabolism of a disulfiram metabolite, S-methyl N, N-diethyldithiocarbamate, by flavin monooxygenase in human renal microsomes
Published in Drug metabolism and disposition (01-02-2001)“…S-Methyl N,N-diethyldithiocarbamate (MeDDC), a metabolite of the alcohol deterrent disulfiram, is converted to MeDDC sulfine and then S-methyl…”
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Inhibition of Recombinant Human Mitochondrial and Cytosolic Aldehyde Dehydrogenases by Two Candidates for the Active Metabolites of Disulfiram
Published in Biochemistry (Easton) (04-11-1997)“…We expressed recombinant human cytosolic (ALDH1, high K m) and mitochondrial aldehyde dehydrogenase (ALDH2, low K m) in Escherichia coli and purified the…”
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Intravenous azathioprine in severe ulcerative colitis: a pilot study
Published in The American journal of gastroenterology (2000)“…OBJECTIVE: Azathioprine use in acute ulcerative colitis has been limited by its perceived long onset of action. The aim of this study was to determine the…”
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Chemical modifications to study mutations that affect the ability of the general base (E268) to function in human liver mitochondrial aldehyde dehydrogenase
Published in Chemico-biological interactions (01-02-2003)“…The action of a general base is needed in two possible steps during the aldehyde dehydrogenase catalyzed oxidation of an aldehyde to an acid. The base is…”
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Tackling illiteracy in Year 7 of the comprehensive school
Published in Support for learning (01-08-2012)“…Reading standards are regarded by many as the true yardstick by which to measure school effectiveness, and the relative standards achieved by different…”
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Clinical outcome and pharmacokinetics after addition of low‐dose cyclosporine to methotrexate: A case study of five patients with treatment‐resistant inflammatory bowel disease
Published in Inflammatory bowel diseases (01-11-2000)“…Introduction: This study reports the clinical outcome, toxicity, and methotrexate pharmacokinetics after the addition of low‐dose cyclosporine to methotrexate…”
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Plasma and rectal adenosine in inflammatory bowel disease: Effect of methotrexate
Published in Inflammatory bowel diseases (01-08-1999)“…In animal models, the antiinflammatory mechanism of action of methotrexate has been attributed to elevation of the extracellular concentration of the…”
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14
Monosulfiram, disulfiram, and light
Published in The Lancet (British edition) (29-01-1994)Get more information
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Pharmacokinetics and tissue distribution of a peptide nucleic acid after intravenous administration
Published in Antisense & nucleic acid drug development (01-04-2002)“…Peptide nucleic acids (PNAs) are DNA analogs that hybridize to complementary nucleic sequences with high affinity and stability. In our previous work, we…”
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Mycotoxin management in maize (Zea mays (L.)) damaged by Lepidopteran pests
Published 01-01-2015“…Mycotoxins are secondary fungal metabolites that pose health risk to both animals and humans. Feeding damage caused Lepidopteran pests is believed to…”
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Dissertation -
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Inhibition of Interleukin-1-stimulated NF-κB RelA/p65 Phosphorylation by Mesalamine Is Accompanied by Decreased Transcriptional Activity
Published in The Journal of biological chemistry (10-09-1999)“…Nuclear factor κB (NF-κB) is an inducible transcription factor that regulates genes important in immunity and inflammation. The activity of NF-κB is highly…”
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Methoxsalen is a potent inhibitor of the metabolism of caffeine in humans
Published in Clinical pharmacology and therapeutics (01-12-1987)“…The acute effect of a single oral dose of methoxsalen on the pharmacokinetics of caffeine was investigated in five nonsmoking volunteers with psoriasis…”
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Lack of effect of intravenous administration on time to respond to azathioprine for steroid-treated Crohn's disease
Published in Gastroenterology (New York, N.Y. 1943) (01-09-1999)“…Background & Aims: Azathioprine is effective for Crohn's disease but acts slowly. A loading dose may decrease the time to response. Methods: A…”
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Metabolism of phenytoin and covalent binding of reactive intermediates in activated human neutrophils
Published in Biochemical pharmacology (31-07-1995)“…Activation of neutrophils by phorbol-12-myristate-13-acetate (PMA) causes rapid production of superoxide radical (O 2 −), leading to the formation of…”
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