Search Results - "Mayr, Melissa"
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Patient-derived head and neck tumor slice cultures: a versatile tool to study oncolytic virus action
Published in Scientific reports (12-09-2022)“…Head and neck cancer etiology and architecture is quite diverse and complex, impeding the prediction whether a patient could respond to a particular cancer…”
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Fold stability during endolysosomal acidification is a key factor for allergenicity and immunogenicity of the major birch pollen allergen
Published in Journal of allergy and clinical immunology (01-05-2016)“…Background The search for intrinsic factors, which account for a protein's capability to act as an allergen, is ongoing. Fold stability has been identified as…”
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Synergistic effects of dendritic cell targeting and laser-microporation on enhancing epicutaneous skin vaccination efficacy
Published in Journal of controlled release (28-11-2017)“…Due to its unique immunological properties, the skin is an attractive target tissue for allergen-specific immunotherapy. In our current work, we combined a…”
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Optimizing culturing conditions in patient derived 3D primary slice cultures of head and neck cancer
Published in Frontiers in oncology (30-03-2023)“…Three-dimensional primary slice cultures (SC) of head and neck squamous cell carcinomas (HNC) are realistic preclinical models. Until now, preserving structure…”
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Cytotoxic response of tumor-infiltrating lymphocytes of head and neck cancer slice cultures under mitochondrial dysfunction
Published in Frontiers in oncology (07-03-2024)“…Head and neck squamous cell carcinomas (HNSCC) are highly heterogeneous tumors. In the harsh tumor microenvironment (TME), metabolic reprogramming and…”
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Abstract 6658: TcE armed oncolytic virus VSV-GP combines oncolysis and T-cell retargeting for improved efficacy
Published in Cancer research (Chicago, Ill.) (22-03-2024)“…Abstract Background: Oncolytic viruses, such as the chimeric vesicular stomatitis virus variant VSV-GP have dual modes of action, direct tumor-cell killing,…”
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