Search Results - "Mayorga, Arthur J"

TRPV1 antagonist JNJ-39439335 (mavatrep) demonstrates proof of pharmacology in healthy men: a first-in-human, double-blind, placebo-controlled, randomized, sequential group study by Manitpisitkul, Prasarn, Brandt, Michael, Flores, Christopher M., Kenigs, Velga, Moyer, John A., Romano, Gary, Shalayda, Kevin, Mayorga, Arthur J.

“…This double-blind, randomized, placebo-controlled, sequential group, phase 1 study was designed to assess in healthy men, the safety, tolerability,…”
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Limitations on the use of the C57BL/6 mouse in the tail suspension test by MAYORGA, Arthur J, LUCKI, Irwin

“…The C57BL/6 is one of the most widely used mouse strains in behavioral, pharmacological, and genetic research but little is known about their response on tests…”
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Sensitivity to the effects of pharmacologically selective antidepressants in different strains of mice by LUCKI, Irwin, DALVI, Ashutosh, MAYORGA, Arthur J

“…Recent advances in neurobehavioral genetics have increased the importance of research on the behavioral patterns of different mouse strains. A comprehensive…”
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A multiple-dose double-blind randomized study to evaluate the safety, pharmacokinetics, pharmacodynamics and analgesic efficacy of the TRPV1 antagonist JNJ-39439335 (mavatrep) by Manitpisitkul, Prasarn, Flores, Christopher M, Moyer, John A, Romano, Gary, Shalayda, Kevin, Tatikola, Kanaka, Hutchison, James S, Mayorga, Arthur J

“…This double-blind (DB), randomized, placebo-controlled, sequential-group, multiple-ascending dose, phase 1 study evaluated safety, pharmacokinetics and…”
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Characterization of the muscarinic receptor subtype mediating pilocarpine-induced tremulous jaw movements in rats by Mayorga, Arthur J, Cousins, Michael S, Trevitt, Jennifer T, Conlan, Aimee, Gianutsos, Gerald, Salamone, John D

“…Four muscarinic receptor antagonists with varying selectivities for the four pharmacologically-defined muscarinic receptor subtypes (M 1–M 4) were administered…”
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The 505(b)(2) New Drug Application by Prue, J. Christopher, Mayorga, Arthur J.

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Similar effects of amphetamine and methylphenidate on the performance of complex operant tasks in rats by Mayorga, Arthur J, Popke, E.Jon, Fogle, C.Matthew, Paule, Merle G

“…Methylphenidate and d-amphetamine are central nervous system stimulants that have been suggested to share certain behavioral and neurochemical effects. The…”
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Efficacy and safety of fulranumab as monotherapy in patients with moderate to severe, chronic knee pain of primary osteoarthritis: a randomised, placebo- and active-controlled trial by Mayorga, A J, Wang, S, Kelly, K M, Thipphawong, J

“…The efficacy and safety of monotherapy with fulranumab, a monoclonal antibody that neutralises human nerve growth factor (NGF), was evaluated compared with…”
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Neostriatal muscarinic receptor subtypes involved in the generation of tremulous jaw movements in rodents: Implications for cholinergic involvement in Parkinsonism by Salamone, John D., Correa, Merce, Carlson, Brian B., Wisniecki, Anna, Mayorga, Arthur J., Nisenbaum, Eric, Nisenbaum, Laura, Felder, Christian

“…Several studies have shown that a number of pharmacological and neurochemical conditions in rats can induce jaw movements that are described as “vacuous” or…”
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Neostriatal muscarinic receptor subtypes involved in the generation of tremulous jaw movements in rodents by Salamone, John D., Correa, Merce, Carlson, Brian B., Wisniecki, Anna, Mayorga, Arthur J., Nisenbaum, Eric, Nisenbaum, Laura, Felder, Christian

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