Search Results - "Mayordomo, José I."
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Sequence variants at the TERT-CLPTM1L locus associate with many cancer types
Published in Nature genetics (01-02-2009)“…The common sequence variants that have recently been associated with cancer risk are particular to a single cancer type or at most two. Following up on our…”
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2
New common variants affecting susceptibility to basal cell carcinoma
Published in Nature genetics (01-08-2009)“…In a follow-up to our previously reported genome-wide association study of cutaneous basal cell carcinoma (BCC), we describe here several new susceptibility…”
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3
Germline sequence variants in TGM3 and RGS22 confer risk of basal cell carcinoma
Published in Human molecular genetics (01-06-2014)“…To search for new sequence variants that confer risk of cutaneous basal cell carcinoma (BCC), we conducted a genome-wide association study of 38.5 million…”
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4
New basal cell carcinoma susceptibility loci
Published in Nature communications (09-04-2015)“…In an ongoing screen for DNA sequence variants that confer risk of cutaneous basal cell carcinoma (BCC), we conduct a genome-wide association study (GWAS) of…”
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5
Common variants on 1p36 and 1q42 are associated with cutaneous basal cell carcinoma but not with melanoma or pigmentation traits
Published in Nature genetics (01-11-2008)“…To search for new sequence variants that confer risk of cutaneous basal cell carcinoma (BCC), we conducted a genome-wide SNP association study of 930…”
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6
Nonpegylated Liposomal Doxorubicin (TLC-D99), Paclitaxel, and Trastuzumab in HER-2-Overexpressing Breast Cancer: A Multicenter Phase I/II Study
Published in Clinical cancer research (01-01-2009)“…Purpose: To determine the recommended dose, cardiac safety, and antitumor activity of nonpegylated liposomal doxorubicin (TLC-D99), paclitaxel, and the…”
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A genome-wide association study yields five novel thyroid cancer risk loci
Published in Nature communications (14-02-2017)“…The great majority of thyroid cancers are of the non-medullary type. Here we report findings from a genome-wide association study of non-medullary thyroid…”
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A germline variant in the TP53 polyadenylation signal confers cancer susceptibility
Published in Nature genetics (01-11-2011)“…To identify new risk variants for cutaneous basal cell carcinoma, we performed a genome-wide association study of 16 million SNPs identified through…”
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9
A variant associated with nicotine dependence, lung cancer and peripheral arterial disease
Published in Nature (03-04-2008)“…Smoking is a leading cause of preventable death, causing about 5 million premature deaths worldwide each year. Evidence for genetic influence on smoking…”
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10
ASIP and TYR pigmentation variants associate with cutaneous melanoma and basal cell carcinoma
Published in Nature genetics (01-07-2008)“…Fair color increases risk of cutaneous melanoma (CM) and basal cell carcinoma (BCC). Recent genome-wide association studies have identified variants affecting…”
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11
Assessing thyroid cancer risk using polygenic risk scores
Published in Proceedings of the National Academy of Sciences - PNAS (17-03-2020)“…Genome-wide association studies (GWASs) have identified at least 10 single-nucleotide polymorphisms (SNPs) associated with papillary thyroid cancer (PTC) risk…”
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European genome-wide association study identifies SLC14A1 as a new urinary bladder cancer susceptibility gene
Published in Human molecular genetics (01-11-2011)“…Three genome-wide association studies in Europe and the USA have reported eight urinary bladder cancer (UBC) susceptibility loci. Using extended case and…”
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Common variants on 9q22.33 and 14q13.3 predispose to thyroid cancer in European populations
Published in Nature genetics (01-04-2009)“…In order to search for sequence variants conferring risk of thyroid cancer we conducted a genome-wide association study in 192 and 37,196 Icelandic cases and…”
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A sequence variant at 4p16.3 confers susceptibility to urinary bladder cancer
Published in Nature genetics (01-05-2010)“…Thorunn Rafnar and colleagues identify a variant on 4p16.3 near FGFR3 associated with increased risk of urinary bladder cancer. They find that the risk allele…”
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A Phase II Study of Weekly Vinorelbine and Trastuzumab in Patients with HER2-Positive Metastatic Breast Cancer
Published in Clinical breast cancer (01-06-2008)“…Abstract Background Trastuzumab combined with cytotoxic agents presents encouraging results in metastatic breast cancer (MBC), but cardiac toxicity limits some…”
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Insertion of an SVA-E retrotransposon into the CASP8 gene is associated with protection against prostate cancer
Published in Human molecular genetics (01-03-2016)“…Transcriptional and splicing anomalies have been observed in intron 8 of the CASP8 gene (encoding procaspase-8) in association with cutaneous basal-cell…”
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Genome-wide association study yields variants at 20p12.2 that associate with urinary bladder cancer
Published in Human molecular genetics (15-10-2014)“…Genome-wide association studies (GWAS) of urinary bladder cancer (UBC) have yielded common variants at 12 loci that associate with risk of the disease. We…”
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GWAS of thyroid stimulating hormone highlights pleiotropic effects and inverse association with thyroid cancer
Published in Nature communications (07-08-2020)“…Thyroid stimulating hormone (TSH) is critical for normal development and metabolism. To better understand the genetic contribution to TSH levels, we conduct a…”
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Granulocyte Colony-Stimulating Factor in the Treatment of High-Risk Febrile Neutropenia: a Multicenter Randomized Trial
Published in JNCI : Journal of the National Cancer Institute (03-01-2001)“…Background: Granulocyte colony-stimulating factors (G-CSFs) have been shown to help prevent febrile neutropenia in certain subgroups of cancer patients…”
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Mutations in BRIP1 confer high risk of ovarian cancer
Published in Nature genetics (01-11-2011)“…Ovarian cancer causes more deaths than any other gynecologic malignancy in developed countries. Sixteen million sequence variants, identified through…”
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