Search Results - "Mayo‐de‐las‐Casas, Clara"

Intermittent BRAF inhibition in advanced BRAF mutated melanoma results of a phase II randomized trial by Gonzalez-Cao, Maria, Mayo de las Casas, Clara, Oramas, Juana, Berciano-Guerrero, Miguel A., de la Cruz, Luis, Cerezuela, Pablo, Arance, Ana, Muñoz-Couselo, Eva, Espinosa, Enrique, Puertolas, Teresa, Diaz Beveridge, Roberto, Ochenduszko, Sebastian, Villanueva, Maria-Jose, Basterretxea, Laura, Bellido, Lorena, Rodriguez, Delvys, Campos, Begoña, Montagut, Clara, Drozdowskyj, Ana, Molina, Miguel A., Lopez-Martin, Jose Antonio, Berrocal, Alfonso

“…Combination treatment with BRAF (BRAFi) plus MEK inhibitors (MEKi) has demonstrated survival benefit in patients with advanced melanoma harboring activating…”
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Prospective detection of mutations in cerebrospinal fluid, pleural effusion, and ascites of advanced cancer patients to guide treatment decisions by Villatoro, Sergio, Mayo‐de‐las‐Casas, Clara, Jordana‐Ariza, Núria, Viteri‐Ramírez, Santiago, Garzón‐Ibañez, Mónica, Moya‐Horno, Irene, García‐Peláez, Beatriz, González‐Cao, María, Malapelle, Umberto, Balada‐Bel, Ariadna, Martínez‐Bueno, Alejandro, Campos, Raquel, Reguart, Noemí, Majem, Margarita, Blanco, Remei, Blasco, Ana, Catalán, María J., González, Xavier, Troncone, Giancarlo, Karachaliou, Niki, Rosell, Rafael, Molina‐Vila, Miguel A.

“…Many advanced cases of cancer show central nervous system, pleural, or peritoneal involvement. In this study, we prospectively analyzed if cerebrospinal fluid…”
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Detection of somatic mutations in peritoneal lavages and plasma of endometrial cancer patients: A proof‐of‐concept study by Mayo‐de‐las‐Casas, Clara, Velasco, Ana, Sanchez, Douglas, Martínez‐Bueno, Alejandro, Garzón‐Ibáñez, Mónica, Gatius, Sònia, Ruiz‐Miró, Maria, Gonzalez‐Tallada, Xavier, Llordella, Ivana, Tresserra, Francesc, Rodríguez, Sonia, Aldeguer, Erika, Roman‐Canal, Berta, Bertran‐Alamillo, Jordi, García‐Peláez, Beatriz, Rosell, Rafael, Molina‐Vila, Miguel A., Matias‐Guiu, Xavier

“…Endometrial cancer (EC) is the most common gynecologic malignancy in developed countries. Although most patients are diagnosed at early stages, 15–20% will…”
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Detecting ALK, ROS1, and RET fusions and the METΔex14 splicing variant in liquid biopsies of non-small-cell lung cancer patients using RNA-based techniques by Giménez-Capitán, Ana, Sánchez-Herrero, Estela, Robado de Lope, Lucía, Aguilar-Hernández, Andrés, Sullivan, Ivana, Calvo, Virginia, Moya-Horno, Irene, Viteri, Santiago, Cabrera, Carlos, Aguado, Cristina, Armiger, Noelia, Valarezo, Joselyn, Mayo-de-Las-Casas, Clara, Reguart, Noemí, Rosell, Rafael, Provencio, Mariano, Romero, Atocha, Molina-Vila, Miguel A

“…ALK, ROS1, and RET fusions and MET∆ex14 variant associate with response to targeted therapies in non-small-cell lung cancer (NSCLC). Technologies for fusion…”
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Brief Research Report: Anti-SARS-CoV-2 Immunity in Long Lasting Responders to Cancer Immunotherapy Through mRNA-Based COVID-19 Vaccination by Sisteré-Oró, Marta, Wortmann, Diana D. J., Andrade, Naína, Aguilar, Andres, Mayo de las Casas, Clara, Casabal, Florencia Garcia, Torres, Susana, Bona Salinas, Eduardo, Raventos Soler, Laura, Arcas, Andrea, Esparre, Carlos, Garcia, Beatriz, Valarezo, Joselyn, Rosell, Rafael, Güerri-Fernandez, Roberto, Gonzalez-Cao, Maria, Meyerhans, Andreas

“…Cancer patients (CPs) have been identified as particularly vulnerable to SARS-CoV-2 infection, and therefore are a priority group for receiving COVID-19…”
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Fluorescence In Situ Hybridization (FISH) for the Characterization and Monitoring of Primary Cultures from Human Tumors by Román-Lladó, Ruth, Aguado, Cristina, Jordana-Ariza, Núria, Roca-Arias, Jaume, Rodríguez, Sonia, Aldeguer, Erika, Garzón-Ibañez, Mónica, García-Peláez, Beatriz, Vives-Usano, Marta, Giménez-Capitán, Ana, Aguilar, Andrés, Martinez-Bueno, Alejandro, Cao, María Gonzalez, García-Casabal, Florencia, Viteri, Santiago, Mayo de las Casas, Clara, Rosell, Rafael, Molina-Vila, Miguel Angel

“…Genetic and drug sensitivity assays on primary cultures are not only of basic but also of translational interest and could eventually aid oncologists in the…”
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Analysis of Copy Number Variations in Solid Tumors Using a Next Generation Sequencing Custom Panel by Vives-Usano, Marta, García Pelaez, Beatriz, Román Lladó, Ruth, Garzón Ibañez, Mónica, Aldeguer, Erika, Rodriguez, Sonia, Aguilar, Andrés, Pons, Francesc, Viteri, Santiago, Cabrera, Carlos, José Catalán, Maria, Moya, Irene, Gonzalez Cao, María, García-Mosquera, Juan José, Martinez-Bueno, Alejandro, Meshoulam, Ekaterina, Jordana, Nuria, Berrocal, Laura, Rosell, Rafael, Molina, Miguel Angel, Mayo de las Casas, Clara

“…Somatic copy number variations (CNV; i.e., amplifications and deletions) have been implicated in the origin and development of multiple cancers and some of…”
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Multiplex Detection of Clinically Relevant Mutations in Liquid Biopsies of Cancer Patients Using a Hybridization-Based Platform by Giménez-Capitán, Ana, Bracht, Jillian, García, Juan José, Jordana-Ariza, Núria, García, Beatriz, Garzón, Mónica, Mayo-de-Las-Casas, Clara, Viteri-Ramirez, Santiago, Martinez-Bueno, Alejandro, Aguilar, Andrés, Sullivan, Ivana-Gabriela, Johnson, Eric, Huang, Chung-Ying, Gerlach, Jay L, Warren, Sarah, Beechem, Joseph M, Teixidó, Cristina, Rosell, Rafael, Reguart, Noemí, Molina-Vila, Miguel A

“…With the advent of precision oncology, liquid biopsies are quickly gaining acceptance in the clinical setting. However, in some cases, the amount of DNA…”
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Acquired BRAF gene fusions in Osimertinib resistant EGFR-mutant non-small cell lung cancer by Rosell, Rafael, González-Cao, María, Codony-Servat, Jordi, Molina-Vila, Miguel Angel, de Las Casas, Clara Mayo, Ito, Masaoki

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Evolution and Clinical Impact of EGFR Mutations in Circulating Free DNA in the BELIEF Trial by Molina-Vila, Miguel-Angel, Stahel, Rolf A, Dafni, Urania, Jordana-Ariza, Núria, Balada-Bel, Ariadna, Garzón-Ibáñez, Mónica, García-Peláez, Beatriz, Mayo-de-Las-Casas, Clara, Felip, Enriqueta, Curioni Fontecedro, Alessandra, Gautschi, Oliver, Peters, Solange, Massutí, Bartomeu, Palmero, Ramon, Ponce Aix, Santiago, Carcereny, Enric, Früh, Martin, Pless, Miklos, Popat, Sanjay, Cuffe, Sinead, Bidoli, Paolo, Kammler, Roswitha, Roschitzki-Voser, Heidi, Tsourti, Zoi, Karachaliou, Niki, Rosell, Rafael

“…Longitudinal evaluation of mutations in blood samples was a prespecified secondary objective in the BELIEF trial of erlotinib and bevacizumab in advanced…”
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Consistency and reproducibility of next‐generation sequencing in cytopathology: A second worldwide ring trial study on improved cytological molecular reference specimens by Pisapia, Pasquale, Malapelle, Umberto, Roma, Gianluca, Saddar, Sonika, Zheng, Qi, Pepe, Francesco, Bruzzese, Dario, Vigliar, Elena, Bellevicine, Claudio, Luthra, Rajyalakshmi, Nikiforov, Yuri E., Mayo‐de‐Las‐Casas, Clara, Molina‐Vila, Miguel Angel, Rosell, Rafael, Bihl, Michel, Savic, Spasenija, Bubendorf, Lukas, de Biase, Dario, Tallini, Giovanni, Hwang, David H., Sholl, Lynette M., Vander Borght, Sara, Weynand, Birgit, Stieber, Daniel, Vielh, Philippe, Rappa, Alessandra, Barberis, Massimo, Fassan, Matteo, Rugge, Massimo, De Andrea, Carlos E., Lozano, Maria D., Lupi, Cristiana, Fontanini, Gabriella, Schmitt, Fernando, Dumur, Catherine I., Bisig, Bettina, Bongiovanni, Massimo, Merkelbach‐Bruse, Sabine, Büttner, Reinhard, Nikiforova, Marina N., Roy‐Chowdhuri, Sinchita, Troncone, Giancarlo

“…Background Artificial genomic reference standards in a cytocentrifuge/cytospin format with well‐annotated genomic data are useful for validating…”
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Consistency and reproducibility of next‐generation sequencing and other multigene mutational assays: A worldwide ring trial study on quantitative cytological molecular reference specimens by Malapelle, Umberto, Mayo‐de‐Las‐Casas, Clara, Molina‐Vila, Miguel A., Rosell, Rafael, Savic, Spasenija, Bihl, Michel, Bubendorf, Lukas, Salto‐Tellez, Manuel, de Biase, Dario, Tallini, Giovanni, Hwang, David H., Sholl, Lynette M., Luthra, Rajyalakshmi, Weynand, Birgit, Vander Borght, Sara, Missiaglia, Edoardo, Bongiovanni, Massimo, Stieber, Daniel, Vielh, Philippe, Schmitt, Fernando, Rappa, Alessandra, Barberis, Massimo, Pepe, Francesco, Pisapia, Pasquale, Serra, Nicola, Vigliar, Elena, Bellevicine, Claudio, Fassan, Matteo, Rugge, Massimo, de Andrea, Carlos E., Lozano, Maria D., Basolo, Fulvio, Fontanini, Gabriella, Nikiforov, Yuri E., Kamel‐Reid, Suzanne, da Cunha Santos, Gilda, Nikiforova, Marina N., Roy‐Chowdhuri, Sinchita, Troncone, Giancarlo

“…BACKGROUND Molecular testing of cytological lung cancer specimens includes, beyond epidermal growth factor receptor (EGFR), emerging predictive/prognostic…”
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Development of a gene panel for next-generation sequencing of clinically relevant mutations in cell-free DNA from cancer patients by Malapelle, Umberto, Mayo de-Las-Casas, Clara, Rocco, Danilo, Garzon, Monica, Pisapia, Pasquale, Jordana-Ariza, Nuria, Russo, Maria, Sgariglia, Roberta, De Luca, Caterina, Pepe, Francesco, Martinez-Bueno, Alejandro, Morales-Espinosa, Daniela, González-Cao, María, Karachaliou, Niki, Viteri Ramirez, Santiago, Bellevicine, Claudio, Molina-Vila, Miguel Angel, Rosell, Rafael, Troncone, Giancarlo

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cfDNA analysis from blood in melanoma by Molina-Vila, Miguel A, de-Las-Casas, Clara Mayo, Bertran-Alamillo, Jordi, Jordana-Ariza, Nuria, González-Cao, María, Rosell, Rafael

“…Testing of tumor tissue remains the recommended method for detecting the presence of somatic mutations in human malignancies. V600E is the most frequent…”
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Usefulness of circulating free DNA for monitoring epidermal growth factor receptor mutations in advanced non-small cell lung cancer patients: a case report by de las Casas, Clara Mayo, Gonzalez-Cao, Maria, Ramirez, Santiago Viteri, Ariza, Nuria Jordana, Balada, Ariadna, Garzón, Mónica, Teixidó, Cristina, Karachaliou, Niki, Morales-Espinosa, Daniela, Molina-Vila, Miguel Ángel, Rosell, Rafael

“…Genomic analysis of circulating tumor DNA (ctDNA) released from cancer cells into the bloodstream has been proposed as a useful method to capture dynamic…”
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Prospective analysis of liquid biopsies of advanced non-small cell lung cancer patients after progression to targeted therapies using GeneReader NGS platform by Mayo de Las Casas, Clara, Garzón-Ibañez, Mónica, Jordana-Ariza, Núria, Viteri-Ramírez, Santiago, Moya-Horno, Irene, Karachaliou, Niki, Yeste, Zaira, Campos, Raquel, Villatoro, Sergi, Balada-Bel, Ariadna, García-Peláez, Beatriz, Reguart, Noemí, Teixidó, Cristina, Jantús, Eloisa, Calabuig, Silvia, Aguado, Cristina, Giménez-Capitán, Ana, Román-Lladó, Ruth, Pérez-Rosado, Ana, Catalán, Maria José, Bertrán-Alamillo, Jordi, García-Román, Silvia, Rodriguez, Sonia, Alonso, Lidia, Aldeguer, Erika, Martínez-Bueno, Alejandro, González-Cao, Maria, Aguilar Hernandez, Andrés, Garcia-Mosquera, Juan, de Los Llanos Gil, Maria, Fernandez, Manuel, Rosell, Rafael, Molina-Vila, Miguel Ángel

“…In a significant percentage of advanced non-small cell lung cancer (NSCLC) patients, tumor tissue is unavailable or insufficient for genetic analyses at time…”
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Abstract 290: Comparison of clinically relevant fusions detection using two multiplexing RNA based platforms: nCounter and GeneReader by Ibañez, Mónica Garzón, Gimenez-Capitán, Ana, Usano, Marta Vives, Lladó, Ruth Román, Rodriguez, Sonia, Aldeguer, Erika, Pelaez, Beatriz García, Ariza, Nuria Jordana, Aguado, Cristina, Viteri, Santiago, Aguilar, Andrés, Moya, Irene, Cabrera, Carlos, Catalán, Maria Jose, cao, Maria Gonzalez, Garcia-Roman, Silvia, Alamillo, Jordi Bertran, Casabal, Florencia Garcia, Rosell, Rafael, Molina-Vila, Miguel Angel, De Las Casas, Clara De La Caridad Mayo

“…Background: Fusions involving the tyrosine kinase receptor genes ALK, ROS1, RET, NTRK or MET exon 14 skipping variant (METex14) are present in a significant…”
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Successful Treatment with Gefitinib in Advanced Non-Small Cell Lung Cancer after Acquired Resistance to Osimertinib by Chic, Nuria, Mayo-de-Las-Casas, Clara, Reguart, Noemí

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The Present and Future of Liquid Biopsies in Non-Small Cell Lung Cancer: Combining Four Biosources for Diagnosis, Prognosis, Prediction, and Disease Monitoring by Bracht, Jillian Wilhelmina Paulina, Mayo-de-las-Casas, Clara, Berenguer, Jordi, Karachaliou, Niki, Rosell, Rafael

“…Purpose of Review Liquid biopsies have potential as tools for diagnosis, prognosis, and prediction of response to therapy. Herein, we will extensively review…”
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Nondisruptive p53 Mutations Are Associated with Shorter Survival in Patients with Advanced Non-Small Cell Lung Cancer by MOLINA-VILA, Miguel A, BERTRAN-ALAMILLO, Jordi, MAJEM, Margarita, MASSUTI, Bartomeu, MORAN, Teresa, CARCERENY, Enric, VITERI, Santiago, ROSELL, Rafael, GASCO, Amaya, MAYO-DE-LAS-CASAS, Clara, SANCHEZ-RONCO, María, PUJANTELL-PASTOR, Laia, BONANNO, Laura, FAVARETTO, Adolfo G, CARDONA, Andrés F, VERGNENEGRE, Alain

“…TP53 mutations in early-stage non-small cell lung cancer (NSCLC) may be associated with worse survival but their prognostic role in advanced NSCLC is…”
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