Search Results - "Maynard, Stephanie A."
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1
Quantitative volumetric Raman imaging of three dimensional cell cultures
Published in Nature communications (22-03-2017)“…The ability to simultaneously image multiple biomolecules in biologically relevant three-dimensional (3D) cell culture environments would contribute greatly to…”
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2
Inhibitory Receptor Diffusion Dynamics
Published in Frontiers in molecular neuroscience (19-12-2019)“…The dynamic modulation of receptor diffusion-trapping at inhibitory synapses is crucial to synaptic transmission, stability, and plasticity. In this review…”
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3
Identification of a stereotypic molecular arrangement of endogenous glycine receptors at spinal cord synapses
Published in eLife (08-12-2021)“…Precise quantitative information about the molecular architecture of synapses is essential to understanding the functional specificity and downstream signaling…”
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4
IL-1β mediated nanoscale surface clustering of integrin α5β1 regulates the adhesion of mesenchymal stem cells
Published in Scientific reports (25-03-2021)“…Clinical use of human mesenchymal stem cells (hMSCs) is limited due to their rapid clearance, reducing their therapeutic efficacy. The inflammatory cytokine…”
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5
Preventing tissue fibrosis by local biomaterials interfacing of specific cryptic extracellular matrix information
Published in Nature communications (08-06-2017)“…Matrix metalloproteinases (MMPs) contribute to the breakdown of tissue structures such as the basement membrane, promoting tissue fibrosis. Here we developed…”
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Quantifying postsynaptic receptor dynamics: insights into synaptic function
Published in Nature reviews. Neuroscience (01-01-2023)“…The molecular composition of presynaptic and postsynaptic neuronal terminals is dynamic, and yet long-term stabilizations in postsynaptic responses are…”
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7
Engineering Extracellular Vesicles with the Tools of Enzyme Prodrug Therapy
Published in Advanced materials (Weinheim) (01-04-2018)“…Extracellular vesicles (EVs) have recently gained significant attention as important mediators of intercellular communication, potential drug carriers, and…”
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Self-Assembled 2D Free-Standing Janus Nanosheets with Single-Layer Thickness
Published in Journal of the American Chemical Society (04-10-2017)“…We report the thermodynamically controlled growth of solution-processable and free-standing nanosheets via peptide assembly in two dimensions. By taking…”
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Cell-geometry-dependent changes in plasma membrane order direct stem cell signalling and fate
Published in Nature materials (01-03-2018)“…Cell size and shape affect cellular processes such as cell survival, growth and differentiation 1 – 4 , thus establishing cell geometry as a fundamental…”
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Nanoscale Molecular Quantification of Stem Cell–Hydrogel Interactions
Published in ACS nano (22-12-2020)“…A common approach to tailoring synthetic hydrogels for regenerative medicine applications involves incorporating RGD cell adhesion peptides, yet assessing the…”
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Spatiotemporal quantification of acoustic cell patterning using Voronoï tessellation
Published in Lab on a chip (12-02-2019)“…Acoustic patterning using ultrasound standing waves has recently emerged as a potent biotechnology enabling the remote generation of ordered cell systems. This…”
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Controlled Sub-Nanometer Epitope Spacing in a Three-Dimensional Self-Assembled Peptide Hydrogel
Published in ACS nano (27-12-2016)“…Cells in the body use a variety of mechanisms to ensure the specificity and efficacy of signal transduction. One way that this is achieved is through tight…”
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Advancing Cell-Instructive Biomaterials Through Increased Understanding of Cell Receptor Spacing and Material Surface Functionalization
Published in Regenerative engineering and translational medicine (01-12-2021)“…Regenerative medicine is aimed at restoring normal tissue function and can benefit from the application of tissue engineering and nano-therapeutics. In order…”
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Drug Delivery: Engineering Extracellular Vesicles with the Tools of Enzyme Prodrug Therapy (Adv. Mater. 15/2018)
Published in Advanced materials (Weinheim) (12-04-2018)“…In article number 1706616, Molly M. Stevens and co‐workers present the incorporation of extracellular vesicles into biocompatible poly(vinyl alcohol)‐based…”
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