Search Results - "Maynard, Robert D"

Genetic analysis of osteoblast activity identifies Zbtb40 as a regulator of osteoblast activity and bone mass by Doolittle, Madison L, Calabrese, Gina M, Mesner, Larry D, Godfrey, Dana A, Maynard, Robert D, Ackert-Bicknell, Cheryl L, Farber, Charles R

“…Osteoporosis is a genetic disease characterized by progressive reductions in bone mineral density (BMD) leading to an increased risk of fracture. Over the last…”
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Daily oral consumption of hydrolyzed type 1 collagen is chondroprotective and anti-inflammatory in murine posttraumatic osteoarthritis by Dar, Qurratul-Ain, Schott, Eric M, Catheline, Sarah E, Maynard, Robert D, Liu, Zhaoyang, Kamal, Fadia, Farnsworth, Christopher W, Ketz, John P, Mooney, Robert A, Hilton, Matthew J, Jonason, Jennifer H, Prawitt, Janne, Zuscik, Michael J

“…Osteoarthritis (OA) is a degenerative joint disease for which there are no disease modifying therapies. Thus, strategies that offer chondroprotective or…”
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Mouse Models and Online Resources for Functional Analysis of Osteoporosis Genome-Wide Association Studies by Maynard, Robert D, Ackert-Bicknell, Cheryl L

“…Osteoporosis is a complex genetic disease in which the number of loci associated with the bone mineral density, a clinical risk factor for fracture, has…”
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Personalized Reproductive Hormone Monitoring in Sweat by Maynard, Robert D

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Concordance of Chronic Kidney Disease Stage and Metformin Management Using CKD-EPI 2021 Race-Free Equation vs CKD-EPI 2009 Equation to Estimate Glomerular Filtration Rate by Maynard, Robert D, Korpi-Steiner, Nichole, Cotten, Steven W

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IKKβ-NF-κB signaling in adult chondrocytes promotes the onset of age-related osteoarthritis in mice by Catheline, Sarah E, Bell, Richard D, Oluoch, Luke S, James, M Nick, Escalera-Rivera, Katherine, Maynard, Robert D, Chang, Martin E, Dean, Christopher, Botto, Elizabeth, Ketz, John P, Boyce, Brendan F, Zuscik, Michael J, Jonason, Jennifer H

“…Canonical nuclear factor κB (NF-κB) signaling mediated by homo- and heterodimers of the NF-κB subunits p65 (RELA) and p50 (NFKB1) is associated with…”
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Monitoring tacrolimus toxicity following Paxlovid administration in a liver transplant patient by Maynard, Robert D., Bates, Phillip, Korpi-Steiner, Nichole

“…Maintaining therapeutic plasma tacrolimus concentrations is essential for mitigating potential solid organ transplant rejection and preventing toxic adverse…”
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Characterization of expression and alternative splicing of the gene cadherin-like and PC esterase domain containing 1 (Cped1) by Maynard, Robert D., Godfrey, Dana A., Medina-Gomez, Carolina, Ackert-Bicknell, Cheryl L.

“…Cadherin-like and PC-esterase domain containing 1 (CPED1) is an uncharacterized gene with no known function. Human genome wide association studies (GWAS) for…”
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Analytical Performance Evaluation of Three Point-of-Care CBC Analyzers for Management of Clozapine Therapy in Ambulatory Psychiatry Clinics by Maynard, Robert D, Funk, Tony, Harrill, William, Jin, Jenny, Smith, Dawn, Smith, Gina, Korpi-Steiner, Nichole

“…Abstract Background Clozapine is a first-line therapy and the only FDA-approved drug for patients with treatment-resistant schizophrenia (TRS). However,…”
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Surgical Induction of Posttraumatic Osteoarthritis in the Mouse by Maynard, Robert D, Villani, David A, Schroeder, William G, Adams, Douglas J, Zuscik, Michael J

“…Given the prevalence and the scope of the personal and societal burden of osteoarthritis (OA), investigators continue to be deeply interested in understanding…”
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Ski inhibits TGF-β/phospho-Smad3 signaling and accelerates hypertrophic differentiation in chondrocytes by Kim, Kyung-Ok, Sampson, Erik R., Maynard, Robert D., O'Keefe, Regis J., Chen, Di, Drissi, Hicham, Rosier, Randy N., Hilton, Matthew J., Zuscik, Michael J.

“…Since transforming growing factor‐β (TGF‐β)/Smad signaling inhibits chondrocyte maturation, endogenous negative regulators of TGF‐β signaling are likely also…”
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Surgical induction of posttraumatic osteoarthritis in the mouse by Hamada, Daisuke, Sampson, Erik R, Maynard, Robert D, Zuscik, Michael J

“…Given the prevalence and the scope of the personal and societal burden of OA, investigators have become increasingly interested in understanding the pathogenic…”
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Establishing the Functional Role of Cped1 in the Genetic Regulation of the Osteoblast by Maynard, Robert D

“…Osteoporosis is a polygenic, inherited disease of progressive bone loss culminating in debilitating low-trauma fractures (bone failure) and increased mortality…”
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Monitoring tacrolimus toxicity following Paxlovid administration in a liver transplant patient by Maynard, Robert D, Bates, Phillip, Korpi-Steiner, Nichole

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