Search Results - "Maynard, Heather D"

Heparin-Mimicking Polymers: Synthesis and Biological Applications by Paluck, Samantha J, Nguyen, Thi H, Maynard, Heather D

“…Heparin is a naturally occurring, highly sulfated polysaccharide that plays a critical role in a range of different biological processes. Therapeutically, it…”
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Therapeutic Protein–Polymer Conjugates: Advancing Beyond PEGylation by Pelegri-O’Day, Emma M, Lin, En-Wei, Maynard, Heather D

“…Protein–polymer conjugates are widely used as therapeutics. All Food and Drug Administration (FDA)-approved protein conjugates are covalently linked to…”
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Preparation of biomolecule-polymer conjugates by grafting-from using ATRP, RAFT, or ROMP by Messina, Marco S., Messina, Kathryn M.M., Bhattacharya, Arvind, Montgomery, Hayden R., Maynard, Heather D.

“…[Display omitted] Biomolecule-polymer conjugates are constructs that take advantage of the functional or otherwise beneficial traits inherent to biomolecules…”
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Tuning Molecular Interactions for Highly Reproducible and Efficient Formamidinium Perovskite Solar Cells via Adduct Approach by Lee, Jin-Wook, Dai, Zhenghong, Lee, Changsoo, Lee, Hyuck Mo, Han, Tae-Hee, De Marco, Nicholas, Lin, Oliver, Choi, Christopher S, Dunn, Bruce, Koh, Jaekyung, Di Carlo, Dino, Ko, Jeong Hoon, Maynard, Heather D, Yang, Yang

“…The Lewis acid–base adduct approach has been widely used to form uniform perovskite films, which has provided a methodological base for the development of…”
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Organometallic Gold(III) Reagents for Cysteine Arylation by Messina, Marco S, Stauber, Julia M, Waddington, Mary A, Rheingold, Arnold L, Maynard, Heather D, Spokoyny, Alexander M

“…An efficient method for chemo­selective cysteine arylation of unprotected peptides and proteins using Au­(III) organometallic complexes is reported. The…”
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Trehalose Glycopolymers for Stabilization of Protein Conjugates to Environmental Stressors by Mancini, Rock J, Lee, Juneyoung, Maynard, Heather D

“…Herein, we report the synthesis of trehalose side chain polymers for stabilization of protein conjugates to environmental stressors. The glycomonomer…”
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Electron-Beam Lithography for Patterning Biomolecules at the Micron and Nanometer Scale by Kolodziej, Christopher M, Maynard, Heather D

“…This review summarizes the use of electron beam (e-beam) lithography to pattern biomolecules on surfaces. The focus is on approaches that employ poly­(ethylene…”
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Substituted Polyesters by Thiol–Ene Modification: Rapid Diversification for Therapeutic Protein Stabilization by Pelegri-O’Day, Emma M, Paluck, Samantha J, Maynard, Heather D

“…Many proteins, especially those used as therapeutics, are unstable to storage and shipping temperatures, leading to increased costs in research and industry…”
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Emerging synthetic approaches for protein-polymer conjugations by Broyer, Rebecca M, Grover, Gregory N, Maynard, Heather D

“…Protein-polymer conjugates are important in diverse fields including drug delivery, biotechnology, and nanotechnology. This feature article highlights recent…”
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Protein–polymer conjugates: synthetic approaches by controlled radical polymerizations and interesting applications by Grover, Gregory N, Maynard, Heather D

“…Protein–polymer conjugates are of interest to researchers in diverse fields. Attachment of polymers to proteins results in improved pharmacokinetics, which is…”
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Trehalose glycopolymer resists allow direct writing of protein patterns by electron-beam lithography by Bat, Erhan, Lee, Juneyoung, Lau, Uland Y., Maynard, Heather D.

“…Direct-write patterning of multiple proteins on surfaces is of tremendous interest for a myriad of applications. Precise arrangement of different proteins at…”
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Controlled Radical Polymerization as an Enabling Approach for the Next Generation of Protein–Polymer Conjugates by Pelegri-O’Day, Emma M, Maynard, Heather D

“…Protein–polymer conjugates are unique constructs that combine the chemical properties of a synthetic polymer chain with the biological properties of a…”
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Atomically precise organomimetic cluster nanomolecules assembled via perfluoroaryl-thiol SNAr chemistry by Qian, Elaine A., Wixtrom, Alex I., Axtell, Jonathan C., Saebi, Azin, Jung, Dahee, Rehak, Pavel, Han, Yanxiao, Moully, Elamar Hakim, Mosallaei, Daniel, Chow, Sylvia, Messina, Marco S., Wang, Jing Yang, Royappa, A. Timothy, Rheingold, Arnold L., Maynard, Heather D., Král, Petr, Spokoyny, Alexander M.

“…The majority of biomolecules are intrinsically atomically precise, an important characteristic that enables rational engineering of their recognition and…”
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A heparin-mimicking polymer conjugate stabilizes basic fibroblast growth factor by Nguyen, Thi H., Kim, Sung-Hye, Decker, Caitlin G., Wong, Darice Y., Loo, Joseph A., Maynard, Heather D.

“…Basic fibroblast growth factor (bFGF) is a protein that plays a crucial role in diverse cellular functions, from wound healing to bone regeneration. However, a…”
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Direct Write Protein Patterns for Multiplexed Cytokine Detection from Live Cells Using Electron Beam Lithography by Lau, Uland Y, Saxer, Sina S, Lee, Juneyoung, Bat, Erhan, Maynard, Heather D

“…Simultaneous detection of multiple biomarkers, such as extracellular signaling molecules, is a critical aspect in disease profiling and diagnostics. Precise…”
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Growth hormone receptor agonists and antagonists: From protein expression and purification to long‐acting formulations by Wang, Yue, Kim, Minah, Buckley, Chantal, Maynard, Heather D., Langley, Ries J., Perry, Jo K.

“…Recombinant human growth hormone (rhGH) and GH receptor antagonists (GHAs) are used clinically to treat a range of disorders associated with GH deficiency or…”
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Trehalose Glycopolymer Enhances Both Solution Stability and Pharmacokinetics of a Therapeutic Protein by Liu, Yang, Lee, Juneyoung, Mansfield, Kathryn M, Ko, Jeong Hoon, Sallam, Sahar, Wesdemiotis, Chrys, Maynard, Heather D

“…Biocompatible polymers such as poly­(ethylene glycol) (PEG) have been successfully conjugated to therapeutic proteins to enhance their pharmacokinetics…”
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Streptavidin as a Macroinitiator for Polymerization:  In Situ Protein−Polymer Conjugate Formation by Bontempo, Debora, Maynard, Heather D

“…This communication reports the first example of polymerization initiated from specific domains on proteins. Streptavidin was coupled with a biotinylated…”
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Trehalose Glycopolymers as Excipients for Protein Stabilization by Lee, Juneyoung, Lin, En-Wei, Lau, Uland Y, Hedrick, James L, Bat, Erhan, Maynard, Heather D

“…Herein, the synthesis of four different trehalose glycopolymers and investigation of their ability to stabilize proteins to heat and lyophilization stress are…”
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Fluorous Comonomer Modulates the Reactivity of Cyclic Ketene Acetal and Degradation of Vinyl Polymers by Ko, Jeong Hoon, Terashima, Takaya, Sawamoto, Mitsuo, Maynard, Heather D

“…Fluorine-containing polymers have potential for use in medicine and other applications, but the synthesis of degradable fluorous polymers is underexplored. In…”
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