Search Results - "Maylie, J"

SK2 and SK3 expression differentially affect firing frequency and precision in dopamine neurons by Deignan, J, Luján, R, Bond, C, Riegel, A, Watanabe, M, Williams, J.T, Maylie, J, Adelman, J.P

“…Highlights ► Dopamine neurons of the substantia nigra express functional SK2 channels. ► SK2 is predominantly expressed in fine dendrites (<1 μM) of nigral…”
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Increasing small conductance Ca2+-activated potassium channel activity reverses ischemia-induced impairment of long-term potentiation by Orfila, J. E., Shimizu, K., Garske, A. K., Deng, G., Maylie, J., Traystman, R. J., Quillinan, N., Adelman, J. P., Herson, P. S.

“…Global cerebral ischemia following cardiac arrest and cardiopulmonary resuscitation (CA/CPR) causes injury to hippocampal CA1 pyramidal neurons and impairs…”
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Mechanism of calcium gating in small-conductance calcium-activated potassium channels by Keen, J. E, Adelman, J. P, Xia, X.-M, Fakler, B, Rivard, A, Wayman, G, Johnson-Pais, T, Ishii, T, Hirschberg, B, Bond, C. T, Lutsenko, S, Maylie, J

“…The slow afterhyperpolarization that follows an action potential is generated by the activation of small-conductance calcium-activated potassium channels (SK…”
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Small-Conductance, Calcium-Activated Potassium Channels from Mammalian Brain by Köhler, M., Hirschberg, B., Bond, C. T., Kinzie, J. M., Marrion, N. V., Maylie, J., Adelman, J. P.

“…Members of a previously unidentified family of potassium channel subunits were cloned from rat and human brain. The messenger RNAs encoding these subunits were…”
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Angiotensin II stimulates hyperplasia but not hypertrophy in immature ovine cardiomyocytes by Sundgren, N C, Giraud, G D, Stork, P J S, Maylie, J G, Thornburg, K L

“…Rat and sheep cardiac myocytes become binucleate as they complete the ‘terminal differentiation’ process soon after birth and are not able to divide…”
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Bicuculline block of small-conductance calcium-activated potassium channels by Khawaled, R, Bruening-Wright, A, Adelman, J P, Maylie, J

“…Small-conductance calcium-activated potassium channels (SK channels) are gated solely by intracellular calcium ions and their activity is responsible for the…”
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Right ventricular systolic pressure load alters myocyte maturation in fetal sheep by Barbera, A, Giraud, G D, Reller, M D, Maylie, J, Morton, M J, Thornburg, K L

“…The effects of right ventricular (RV) systolic pressure (RVSP) load on fetal myocyte size and maturation were studied. Pulmonary artery (PA) pressure was…”
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Induction of endogenous channels by high levels of heterologous membrane proteins in Xenopus oocytes by Tzounopoulos, T., Maylie, J., Adelman, J.P.

“…Xenopus oocytes are widely employed for heterologous expression of cloned proteins, particularly electrogenic molecules such as ion channels and transporters…”
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Small-conductance Ca2+-activated K+ channels: form and function by Adelman, John P, Maylie, James, Sah, Pankaj

“…Small-conductance Ca(2+)-activated K(+) channels (SK channels) are widely expressed throughout the central nervous system. These channels are activated solely…”
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The novel class III antiarrhythmics NE-10064 and NE-10133 inhibit IsK channels expressed in Xenopus oocytes and IKs in guinea pig cardiac myocytes by Busch, A E, Malloy, K, Groh, W J, Varnum, M D, Adelman, J P, Maylie, J

“…Slowly activating, voltage-dependent IsK channels were expressed in Xenopus oocytes after injection of rat IsK protein cRNA and recorded with the…”
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Episodic Ataxia Mutations in Kv1.1 Alter Potassium Channel Function by Dominant Negative Effects or Haploinsufficiency by Zerr, Patricia, Adelman, John P, Maylie, James

“…Subunits of the voltage-gated potassium channel Kv1.1 containing mutations responsible for episodic ataxia (EA), a human inherited neurological disease, were…”
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Episodic Ataxia Type 1 Mutations in the Human Kv1.1 Potassium Channel Alter hKv beta 1-Induced N-Type Inactivation by Maylie, B, Bissonnette, E, Virk, M, Adelman, J P, Maylie, J G

“…Episodic ataxia type 1 (EA1) is an autosomal dominant neurological disorder affecting both central and peripheral nerve function, causing attacks of imbalance…”
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The min K channel underlies the cardiac potassium current IKs and mediates species-specific responses to protein kinase C by VARNUM, M. D, BUSCH, A. E, BOND, C. T, MAYLIE, J, ADELMAN, J. P

“…A clone encoding the guinea pig (gp) min K potassium channel was isolated and expressed in Xenopus oocytes. The currents, gpIsK, exhibit many of the…”
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Stimulation-dependent facilitation of the high threshold calcium current in guinea-pig ventricular myocytes by Zygmunt, A C, Maylie, J

“…1. Stimulation-dependent modulation of Ca currents was examined in guinea-pig ventricular myocytes at room temperature. Whole-cell recordings of Ca currents…”
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Min K Channels Form by Assembly of at Least 14 Subunits by Tzounopoulos, T., Guy, H. R., Durell, S., Adelman, J. P., Maylie, J.

“…Injection of min K mRNA into Xenopus oocytes results in expression of slowly activating voltage-dependent potassium channels, distinct from those induced by…”
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Excitation-contraction coupling in neonatal and adult myocardium of cat by Maylie, J G

“…Neonatal cardiac cells were smaller in diameter, having a lower concentration of myofilaments than cardiac cells of the adult cat. The sarcoplasmic…”
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New sites of action for GIRK and SK channels by Luján, Rafael, Maylie, James, Adelman, John P

“…GIRK and SK channels, two families of voltage-independent K + channels, have recently been described at synaptic as well as extrasynaptic sites. Luján and…”
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SK channels and NMDA receptors form a Ca2+-mediated feedback loop in dendritic spines by Ngo-Anh, Thu Jennifer, Bloodgood, Brenda L, Lin, Michael, Sabatini, Bernardo L, Maylie, James, Adelman, John P

“…Small-conductance Ca(2+)-activated K(+) channels (SK channels) influence the induction of synaptic plasticity at hippocampal CA3-CA1 synapses. We find that in…”
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Hypotonic-induced stretch counteracts the efficacy of the class III antiarrhythmic agent E-4031 in guinea pig myocytes by GROH, W. J, GIBSON, K. J, MAYLIE, J. G

“…The aim was to determine the effect and mechanisms by which myocyte stretch interacts with the prolongation of action potential duration (APD) by the class III…”
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Evaluation of T- and L-type Ca2+ currents in shark ventricular myocytes by Maylie, J, Morad, M

“…Two types of Ca2+ currents with characteristics of T- and L-type Ca2+ currents were recorded in ventricular myocytes of dogfish (Squalus acanthias). The T-type…”
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